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Recent advances in tannic acid-based gels: Design, properties, and applications
Abstract
With the flourishing of mussel-inspired chemistry, the fast-growing development for environmentally friendly materials, and the need for inexpensive and biocompatible analogues to PDA in gel design, TA has led to its gradual emergence as a research focus due to its remarkable biocompatible, renewable, sustainable and particular physicochemical properties. As a natural building block, TA can be used as a substrate or crosslinker, ensuring versatile functional polymeric networks for various applications. In this review, the design of TA-based gels is summarized in detail (i.e., different interactions such as: metal coordination, electrostatic, hydrophobic, host-guest, cation-π and π-π stacking interactions, hydrogen bonding and various reactions including: phenol-amine Michael and Schiff base, phenol-thiol Michael addition, phenol-epoxy ring opening reaction, etc.). Subsequently, TA-based gels with a variety of functionalities, including mechanical, adhesion, conductive, self-healing, UV-shielding, anti-swelling, anti-freezing, shape memory, antioxidant, antibacterial, anti-inflammatory and responsive properties are introduced in detail. Then, a summary of recent developments in the use of TA-based gels is provided, including bioelectronics, biomedicine, energy, packaging, water treatment and other fields. Finally, the difficulties that TA-based gels are currently facing are outlined, and an original yet realistic viewpoint is provided in an effort to spur future development.
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“Additionally, quinone structures are capable of undergoing Michael addition reactions with protein thiols or amino groups, thereby enhancing the integration between the coating and the surrounding tissue48.”
From Intelligence-responsive wettability switch coating on magnesium implants for treating osteoporotic fracture (2026) · cites this paper as [48]
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Metadata
- Authors
- Tang, Z., Chowdhury, I. F., Yang, J., Li, S., Mondal, A. K., & Wu, H.
- Affiliations
- Fujian Polytechnic Normal University (CN)
- Bangladesh Council of Scientific and Industrial Research (BD)
- Fujian Agriculture and Forestry University (CN)
- Corresponding author
- Mondal, Ajoy Kanti
- Wu, Hui
- Venue
- Advances in Colloid and Interface Science
- Publisher
- Elsevier BV
- Published
- 2025-05
- Volume
- 339
- Pages
- 103425
- ISSN
- 0001-8686 (ISSN-L)
- OpenAlex
- W4407596944
- Cited by
- 70
- References
- 509
- Citations by year
- 2026: 38 · 2025: 32
- FWCI
- 4.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Advances in Colloid and Interface Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China
- Topics
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Materials Science › Biomaterials › Supramolecular Self-Assembly in Materials
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Keywords
- tannic acid, mussel-inspired chemistry, crosslinking, metal coordination, host-guest interactions, cation-π interactions, π-π stacking, hydrogen bonding, Schiff base, Michael addition, self-healing gels, shape memory effect, conductive gels, antibacterial gel, anti-inflammatory gel, responsive gels, bioelectronics, water treatment, packaging, energy materials, biomedicine
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