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Cited by 109Fungal Infections and StudiesActinomycetales infections and treatmentAntifungal resistance and susceptibility

Paracoccidioidomycosis

Marques, Sílvio Alencar·2012·Clinics in Dermatology
DOI 10.1016/j.clindermatol.2012.01.006
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Abstract

Paracoccidioidomycosis is an endemic systemic mycosis that predominates in southern Mexico, parts of Central America, and South America. It is caused by a dimorphic fungus and is generally acquired through the lungs, from where it disseminates. Paracoccidioidomycosis has different clinical manifestations that require differentiation with tuberculosis, Hodgkin disease, several systemic and subcutaneous mycoses, and squamous cell carcinoma. Diagnosis is made by finding the organism in a biopsy specimen and isolating it in fungal culture. Treatment includes sulfamethoxazole-trimethoprim for mild forms and itraconazole for moderate cases. Fluconazole and voriconazole can be used for meningeal involvement, and amphotericin B is indicated for severe disease.

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Crossref · 10.1016/j.clindermatol.2012.01.006

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  • Coccidioides immitis, Paracoccidioides brasiliensis, and Blastomyces dermatitidis are all sources of mycoses in immunocompromised individuals and have also caused endemic outbreaks in specific geographical regions.

    “Along with H. capsulatum, Coccidioides immitis, Paracoccidioides brasiliensis, and Blastomyces dermatitidis are all sources of mycoses in immunocompromised individuals and have also caused endemic outbreaks in specific geographical regions (62, 113).”

    From <i>Candida albicans</i> Biofilms and Human Disease (2015) · cites this paper as [113]

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Authors
Marques, S. A.
Affiliations
Universidade Estadual Paulista (Unesp) (BR)
Corresponding author
Marques, Sílvio Alencar
ORCID
Marques, Sílvio Alencar
Venue
Clinics in Dermatology
Publisher
Elsevier BV
Published
2012-11
Volume
30
Issue
6
Pages
610-615
ISSN
0738-081X (ISSN-L)
DOI
10.1016/j.clindermatol.2012.01.006
OpenAlex
W4255914008
Cited by
109
References
24
Citations by year
2026: 2 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 7 · 2021: 4 · 2020: 8 · 2019: 6 · 2018: 11 · 2017: 15 · 2016: 12 · 2015: 19 · 2014: 11 · 2013: 4
FWCI
8.14
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Clinics in Dermatology (publishedVersion)
  • PubMed (publishedVersion)
  • Acervo Digital da Universidade Estadual Paulista (Universidade Estadual Paulista) (submittedVersion)
  • UNESP Institutional Repository (São Paulo State University) (submittedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
  • Health Sciences › Medicine › Microbiology › Actinomycetales infections and treatment
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Keywords
paracoccidioidomycosis, systemic fungal infection, dimorphic fungi, pulmonary dissemination, differential diagnosis, tuberculosis, Hodgkin's disease, fungal culture, trimethoprim-sulfamethoxazole, itraconazole, fluconazole, voriconazole, amphotericin B, meningeal involvement, endemic fungal infection
MeSH terms
Antifungal Agents, Humans, Paracoccidioides, Paracoccidioidomycosis

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