Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1α

Brown Adipose Tissue: Function and Physiological Significance

CANNON, B., & NEDERGAARD, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00015.2003 · Cited by 6,433

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., Troy, A., Cinti, S., Lowell, B., Scarpulla, R. C., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80611-x · Cited by 4,139

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator

Puigserver, P., & Spiegelman, B. M. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0012 · Cited by 2,076

Effects of an Rb mutation in the mouse

Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A., & Weinberg, R. A. (1992) · Nature · doi:10.1038/359295a0 · Cited by 1,755

Molecular Regulation of Adipogenesis

Rosen, E. D., & Spiegelman, B. M. (2000) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.16.1.145 · Cited by 1,309

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

Lee, E. Y.-H. P., Chang, C.-Y., Hu, N., Wang, Y.-C. J., Lai, C., Herrup, K., Lee, W., & Bradley, A. (1992) · Nature · doi:10.1038/359288a0 · Cited by 1,264

Requirement for a functional Rb-1 gene in murine development

Clarke, A. R., Maandag, E. R., van ROON, M. A., van der Lugt, N. M. T., van der Valk, M., Hooper, M., Berns, A. J. M., & Rielef, H. T. (1992) · Nature · doi:10.1038/359328a0 · Cited by 1,006

A systems perspective on brown adipogenesis and metabolic activation

Pradhan, R., Zachara, M., & Deplancke, B. (2017) · Obesity Reviews · doi:10.1111/obr.12512 · Cited by 37

Recent progress in the study of brown adipose tissue

Yao, X., Shan, S., Zhang, Y., & Ying, H. (2011) · Cell & Bioscience · doi:10.1186/2045-3701-1-35 · Cited by 35

Mitochondrial thermogenesis and obesity

Gambert, S., & Ricquier, D. (2007) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3282f0b69d · Cited by 33

p107 Is a Crucial Regulator for Determining the Adipocyte Lineage Fate Choices of Stem Cells

Sousa, M. D., Porras, D. P., Perry, C. G. R., Seale, P., & Scimè, A. (2014) · Stem Cells · doi:10.1002/stem.1637 · Cited by 32

Transcriptional Pathways in cPGI2-Induced Adipocyte Progenitor Activation for Browning

Bayindir‐Buchhalter, I., Babaeikelishomi, R., Kocanova, S., Sousa, I. S., Lerch, S., Hardt, O., Wild, S., Bosio, A., Bystricky, K., Herzig, S., et al. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00129 · Cited by 37

Of mice and men: novel insights regarding constitutive and recruitable brown adipocytes

Townsend, K. L., & Tseng, Y.-H. (2015) · International Journal of Obesity Supplements · doi:10.1038/ijosup.2015.5 · Cited by 32

Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning

Patil, M., Sharma, B. K., Elattar, S., Chang, J., Kapil, S., Yuan, J., & Ande, S. (2017) · Diabetes · doi:10.2337/db16-1079 · Cited by 31

Genetic backgrounds determine brown remodeling of white fat in rodents

Ferrannini, G., Namwanje, M., Fang, B., Damle, M., Li, D., Liu, Q., Lazar, M. A., & Qiang, L. (2016) · Molecular Metabolism · doi:10.1016/j.molmet.2016.08.013 · Cited by 33

Muscle injury-induced hypoxia alters the proliferation and differentiation potentials of muscle resident stromal cells

Drouin, G., Couture, V., Lauzon, M.-A., Balg, F., Faucheux, N., & Grenier, G. (2019) · Skeletal Muscle · doi:10.1186/s13395-019-0202-5 · Cited by 32

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2

Mushtaq, M., Kovalevska, L. M., Darekar, S. D., Abramsson, A., Zetterberg, H., Kashuba, V. I., Klein, G., Arsenian‐Henriksson, M., & Kashuba, E. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1922535117 · Cited by 31

Browning and Graying: Novel Transcriptional Regulators of Brown and Beige Fat Tissues and Aging

Mueller, E. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00019 · Cited by 30

Advances in myogenic cell transplantation and skeletal muscle tissue engineering

Scimè, A. (2009) · Frontiers in bioscience · doi:10.2741/3431 · Cited by 30

Emerging Roles for the INK4a/ARF (CDKN2A) Locus in Adipose Tissue: Implications for Obesity and Type 2 Diabetes

Kahoul, Y., Oger, F., Montaigne, J., Froguel, P., Breton, C., & Annicotte, J. (2020) · Biomolecules · doi:10.3390/biom10091350 · Cited by 31

Neuropilin 1 Mediates Keratinocyte Growth Factor Signaling in Adipose-Derived Stem Cells: Potential Involvement in Adipogenesis

Ceccarelli, S., Nodale, C., Vescarelli, E., Pontecorvi, P., Manganelli, V., Casella, G., Onesti, M. G., Sorice, M., Romano, F., Angeloni, A., et al. (2018) · Stem Cells International · doi:10.1155/2018/1075156 · Cited by 29

Hzf regulates adipogenesis through translational control of C/EBPα

Kawagishi, H., Wakoh, T., Uno, H., Maruyama, M., Moriya, A., Morikawa, S., Okano, H., Sherr, C. J., Takagi, M., & Sugimoto, M. (2008) · The EMBO Journal · doi:10.1038/emboj.2008.76 · Cited by 28

Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development

Vernochet, C., Peres, S. B., & Farmer, S. R. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07302.x · Cited by 28

The Retinoblastoma Protein and Its Homolog p130 Regulate the G1/S Transition in Pancreatic β-Cells

Harb, G., Vasavada, R. C., Cobrinik, D. E., & Stewart, A. F. (2009) · Diabetes · doi:10.2337/db08-0759 · Cited by 29

Opportunities and challenges in three-dimensional brown adipogenesis of stem cells

Unser, A. M., Tian, Y. I., & Xie, Y. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.07.005 · Cited by 29

Mitochondrial uncoupling as a target in the treatment of obesity

Costford, S. R., Gowing, A., & Harper, M. (2007) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e3282f0dbe4 · Cited by 26

RNA-Seq reveals miRNA role in thermogenic regulation in brown adipose tissues of goats

Liu, X., Zhu, Y., Zhan, S., Zhong, T., Guo, J., Cao, J., Li, L., Zhang, H., & Wang, L. (2022) · BMC Genomics · doi:10.1186/s12864-022-08401-2 · Cited by 25

Thermogenic Fat: Development, Physiological Function, and Therapeutic Potential

Brandão, B. B., Poojari, A., & Rabiee, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115906 · Cited by 25

Control of Adipose Cell Browning and Its Therapeutic Potential

Lizcano, F., & Arroyave, F. (2020) · Metabolites · doi:10.3390/metabo10110471 · Cited by 23

Conditionally immortalized white preadipocytes: a novel adipocyte model

Morganstein, D. L., Christian, M., Turner, J. J. O., Parker, M. G., & White, R. (2007) · Journal of Lipid Research · doi:10.1194/jlr.d700029-jlr200 · Cited by 23

The Genetic Basis of Baculum Size and Shape Variation in Mice

Schultz, N. G., Ingels, J. F., Hillhouse, A., Wardwell, K., Chang, P. L., Cheverud, J. M., Lutz, C. M., Lu, L., Williams, R. W., & Dean, M. D. (2016) · G3 Genes Genomes Genetics · doi:10.1534/g3.116.027888 · Cited by 23

Transcriptional brakes on the road to adipocyte thermogenesis

Shao, M., & Gupta, R. K. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.05.010 · Cited by 22

Ras signalling regulates differentiation and UCP1 expression in models of brown adipogenesis

Murholm, M., Dixen, K., & Hansen, J. B. (2010) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2010.03.008 · Cited by 21

Oxidative status of muscle is determined by p107 regulation of PGC-1α

Scimè, A., Soleimani, V. D., Bentzinger, C. F., Gillespie, M. A. K., Grand, F. L., Grenier, G., Bevilacqua, L., Harper, M., & Rudnicki, M. A. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201005076 · Cited by 23

Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cells.

Cobrinik, D. E., Francis, R. O., Abramson, D. H., & Lee, T. C. (2006) · Molecular Cancer · doi:10.1186/1476-4598-5-72 · Cited by 20

Development, activation, and therapeutic potential of thermogenic adipocytes

Emont, M. P., Kim, D., & Wu, J. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2018.05.004 · Cited by 20

Pioglitazone does not synergize with mirabegron to increase beige fat or further improve glucose metabolism

Finlin, B. S., Memetimin, H., Zhu, B., Confides, A. L., Vekaria, H. J., Khouli, R. H. E., Johnson, Z., Westgate, P. M., Chen, J., Morris, A. J., et al. (2021) · JCI Insight · doi:10.1172/jci.insight.143650 · Cited by 19

Transcriptional control and hormonal response of thermogenic fat

Emont, M. P., Yu, H. M., & Wu, J. (2015) · Journal of Endocrinology · doi:10.1530/joe-15-0026 · Cited by 19

EndoG Knockout Mice Show Increased Brown Adipocyte Recruitment in White Adipose Tissue and Improved Glucose Homeostasis

Pardo, R., Blasco, N., Vilà, M., Beiroa, D., Nogueiras, R., Cañas, X., Simó, R., Sanchı́s, D., & Villena, J. A. (2016) · Endocrinology · doi:10.1210/en.2015-1334 · Cited by 19

Rose hip supplementation increases energy expenditure and induces browning of white adipose tissue

Cavalera, M., Axling, U., Berger, K., & Holm, C. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0151-5 · Cited by 21

CREG1 promotes uncoupling protein 1 expression and brown adipogenesisin vitro

Kusudo, T., Hashimoto, M., Kataoka, N., Li, Y., Nozaki, A., & Yamashita, H. (2018) · The Journal of Biochemistry · doi:10.1093/jb/mvy083 · Cited by 19

The p107/E2F Pathway Regulates Fibroblast Growth Factor 2 Responsiveness in Neural Precursor Cells

McClellan, K. A., Vanderluit, J. L., Julian, L. M., Andrusiak, M. G., Dugal-Tessier, D., Park, D. S., & Slack, R. S. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01767-08 · Cited by 19

Retinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategies

Kohno, S., Kitajima, S., Sasaki, N., & Takahashi, C. (2016) · World Journal of Stem Cells · doi:10.4252/wjsc.v8.i4.170 · Cited by 18

Pharmacologically targetable vulnerability in prostate cancer carrying RB1-SUCLA2 deletion

Kohno, S., Linn, P., Nagatani, N., Watanabe, Y., Kumar, S., Soga, T., & Takahashi, C. (2020) · Oncogene · doi:10.1038/s41388-020-1381-6 · Cited by 18

Regulation of human subcutaneous adipocyte differentiation by EID1

Vargas, D., Shimokawa, N., Kaneko, R., Rosales, W., Parra, A., Castellanos, Á., Koibuchi, N., & Lizcano, F. (2015) · Journal of Molecular Endocrinology · doi:10.1530/jme-15-0148 · Cited by 16

EID1-induces brown-like adipocyte traits in white 3T3-L1 pre-adipocytes

Lizcano, F., & Vargas, D. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.06.034 · Cited by 15

Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate

Cai, E. P., Wu, X., Schroer, S. A., Elia, A., Nostro, M. C., Zacksenhaus, E., & Woo, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1303386110 · Cited by 16

p107 mediated mitochondrial function controls muscle stem cell proliferative fates

Bhattacharya, D., Shah, V., Oresajo, O., & Scimè, A. (2021) · Nature Communications · doi:10.1038/s41467-021-26176-0 · Cited by 18

Intricate Transcriptional Networks of Classical Brown and Beige Fat Cells

Park, J. H., Hur, W., & Lee, S. B. (2015) · Frontiers in Endocrinology · doi:10.3389/fendo.2015.00124 · Cited by 16

Molecular and cellular regulation of thermogenic fat

Wang, C., Wang, X., & Hu, W. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1215772 · Cited by 14

Critical Role of the Rb Family in Myoblast Survival and Fusion

Ciavarra, G., Ho, A. T. V., Cobrinik, D. E., & Zacksenhaus, E. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017682 · Cited by 15

Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation

Hakim-Weber, R., Krogsdam, A., Jørgensen, C., Fischer, M., Prokesch, A., Bogner‐Strauß, J. G., Bornstein, S. R., Hansen, J. B., Madsen, L., Kristiansen, K., et al. (2011) · BMC Research Notes · doi:10.1186/1756-0500-4-157 · Cited by 13

The Role of Metabolic Changes in Shaping the Fate of Cancer-Associated Adipose Stem Cells

Cantini, G., Franco, A. D., Mannelli, M., Scimè, A., Maggi, M., & Luconi, M. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00332 · Cited by 13

Of mice without pockets: mouse models to study the function of Rb family proteins

Vidal, A. (2007) · Frontiers in bioscience · doi:10.2741/2403 · Cited by 13

Chromatin remodeling and epigenetic regulation of the CrabpI gene in adipocyte differentiation

Wei, L. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.03.003 · Cited by 13

RB Family Tumor Suppressor Activity May Not Relate to Active Silencing of E2F Target Genes

Vormer, T. L., Wojciechowicz, K., Dekker, M., de Vries, S., van der Wal, A., Delzenne‐Goette, E., Naik, S. H., Song, J., Dannenberg, J., Hansen, J. B., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-3706 · Cited by 13

Src family kinases suppress differentiation of brown adipocytes and browning of white adipocytes

Usui, M., Uno, M., & Nishida, E. (2016) · Genes to Cells · doi:10.1111/gtc.12340 · Cited by 13

Deciphering the regulation of porcine genes influencing growth, fatness and yield-related traits through genetical genomics

Martínez-Montes, Á. M., Muiños-Bühl, A., Fernández, A., Folch, J. M., Ibáñez‐Escriche, N., & Fernández, A. I. (2016) · Mammalian Genome · doi:10.1007/s00335-016-9674-3 · Cited by 13

GFP reporter mice for the retinoblastoma-related cell cycle regulator p107

Burkhart, D. L., Viatour, P., Ho, V. M., & Sage, J. (2008) · Cell Cycle · doi:10.4161/cc.7.16.6441 · Cited by 12

p107 Deficiency Increases Energy Expenditure by Inducing Brown‐Fat Thermogenesis and Browning of White Adipose Tissue

Cuñarro, J., Buqué, X., Casado, S., Lugilde, J., Vidal, A., Mora, A., Sabio, G., Nogueiras, R., Aspichueta, P., Diéguez, C., et al. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201801096 · Cited by 11

E2F4 cooperates with pRB in the development of extra-embryonic tissues

Lee, E. Y., Yuan, T. L., Danielian, P. S., West, J. C., & Lees, J. A. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.05.541 · Cited by 10

Feeding the heat on brown fat

Sellayah, D., & Sikder, D. S. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12276 · Cited by 10

Cell‐Autonomous Brown‐Like Adipogenesis of Preadipocytes From Retinoblastoma Haploinsufficient Mice

Petrov, P., Palou, A., Bonet, M. L., & Ribot, J. (2016) · Journal of Cellular Physiology · doi:10.1002/jcp.25299 · Cited by 9

A Closer Look into White Adipose Tissue Biology and the Molecular Regulation of Stem Cell Commitment and Differentiation

Dowker-Key, P. D., Kumar, J. P., Gill, N. B., Hubbard, K. N., Elshaarrawi, A., Alfatlawy, N. D., & Bettaieb, A. (2024) · Genes · doi:10.3390/genes15081017 · Cited by 13

The LXCXE Retinoblastoma Protein-Binding Motif of FOG-2 Regulates Adipogenesis

Goupille, O., Penglong, T., Kadri, Z., Granger-Locatelli, M., Denis, R., Luquet, S. H., Badoual, C., Fucharoen, S., Maouche-Chrétien, L., Leboulch, P., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.11.098 · Cited by 8

p107 Determines a Metabolic Checkpoint Required for Adipocyte Lineage Fates

Porras, D. P., Abbaszadeh, M., Bhattacharya, D., D’Souza, N. C., Edjiu, N. R., Perry, C. G. R., & Scimè, A. (2017) · Stem Cells · doi:10.1002/stem.2576 · Cited by 10

A new era for brown adipose tissue: New insights into brown adipocyte function and differentiation*

Vila‐Bedmar, R., & Fernández‐Veledo, S. (2011) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2011.560951 · Cited by 7

The histone methyltransferase SUV420H2 regulates brown and beige adipocyte thermogenesis

Cui, X., Cao, Q., Li, F., Jing, J., Liu, Z., Yang, X., Schwartz, G. J., Yu, L., Shi, H., Shi, H., et al. (2024) · JCI Insight · doi:10.1172/jci.insight.164771 · Cited by 6

Diet-induced obesity and aging-induced upregulation of Trib3 interfere with energy homeostasis by downregulating the thermogenic capacity of BAT

Yeo, H., Lim, J. H., Eom, J., Kim, M., Kwon, H., Kang, S.-W., & Song, Y. (2024) · Experimental & Molecular Medicine · doi:10.1038/s12276-024-01361-5 · Cited by 6

In Vitro Models for Study of Brown Adipocyte Biology

Christian, M. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_122 · Cited by 6

DEPP Deficiency Contributes to Browning of White Adipose Tissue

Guo, F., Zhu, Y., Han, Y., Feng, X., Pan, Z., He, Y., Li, Y., & Jin, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126563 · Cited by 6

Malonate induces the browning of white adipose tissue in high-fat diet induced obesity model

Oki, S., Kageyama, S., Morioka, Y., & Namba, T. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.08.054 · Cited by 6

miR17-92 cluster drives white adipose tissue browning

Huang, Y., Zhang, H., Dong, M., Zhang, L., Lin, J., Ye, R., Zhou, H., Liu, X., & Jin, W. (2020) · Journal of Molecular Endocrinology · doi:10.1530/jme-20-0032 · Cited by 6

Emerging Roles of Cell Cycle Regulators in Adipocyte Metabolism

Carine Chavey, A., Lagarrigue, S., Annicotte, J., & Lluis Fajas, A. (2012) · Springer eBooks · doi:10.1007/978-2-8178-0343-2_2 · Cited by 6

CDK4/6 are necessary for UCP1-mediated thermogenesis of white adipose tissue

Portales, A. E., Miguel, I., Rodriguez, M. J., Novaro, V., Gambaro, S. E., & Giovambattista, A. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121652 · Cited by 5

Le double jeu des régulateurs du cycle cellulaire

Lagarrigue, S., Blanchet, É., Annicotte, J., & Fajas, L. (2011) · médecine/sciences · doi:10.1051/medsci/2011275016 · Cited by 5

Decreased transcriptional corepressor p107 is associated with exercise‐induced mitochondrial biogenesis in human skeletal muscle

Bhattacharya, D., Ydfors, M., Hughes, M. C., Norrbom, J., Perry, C. G. R., & Scimè, A. (2017) · Physiological Reports · doi:10.14814/phy2.13155 · Cited by 5

RB1 controls differentiation through positive regulation of phosphoglycerate mutases

Kohno, S., Okahashi, N., Wan, Y., Yu, H., Takegami, Y., Linn, P., Nagatani, N., Kitajima, S., Kawada, T., Matsuda, F., et al. (2025) · Cell Death and Disease · doi:10.1038/s41419-025-07850-3 · Cited by 4

Brown and Beige Fat: Therapeutic Potential in Obesity

Meiliana, A., & Wijaya, A. (2014) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v6i2.32 · Cited by 3

Potential novel therapeutic strategies from understanding adipocyte transdifferentiation mechanisms

Sartini, L., & Frontini, A. (2014) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.2015.983474 · Cited by 2

Proteomic differences between white and brown adipocytes

Chen, W., Li, L., & Lübec, G. (2014) · Amino Acids · doi:10.1007/s00726-013-1657-z · Cited by 2

Brown Adipose Tissue: A New Target for Antiobesity Therapy

Meiliana, A., & Wijaya, A. (2010) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v2i2.115 · Cited by 2

Retinoblastoma patient-derived stem cells—an in vivo model to study the role of RB1 in adipogenesis

Vincent, A., Natarajan, V., Khetan, V., Krishnakumar, S., & Parameswaran, S. (2022) · Histochemistry and Cell Biology · doi:10.1007/s00418-022-02105-0 · Cited by 2

Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes

Jeon, Y. G., Kim, S. W., & Kim, J. B. (2024) · Adipocyte · doi:10.1080/21623945.2024.2391511 · Cited by 2

Future Perspectives of Metabolomics in Adipocytes

Tiziani, S. (2014) · Journal of Nutritional Health & Food Science · doi:10.15226/jnhfs.2014.00117 · Cited by 1

Role of PPARγ in adipocyte recruitment and thermogenesis

Nora, E. D., Gray, S. L., & Vidal‐Puig, A. (2007) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.2.5.641 · Cited by 1

Rôle émergent des acteurs du cycle cellulaire dans le métabolisme de l’adipocyte

Carine Chavey, A., Lagarrigue, S., Annicotte, J., & Lluis Fajas, A. (2013) · Springer eBooks · doi:10.1007/978-2-8178-0332-6_2 · Cited by 1

Controlling Thermogenesis: Understanding the Role of PRDM16 in the Development and Function of Brown Fat

Harms, M. (2015) · Scholarly Commons (University of Pennsylvania) · Cited by 1

The Role of Tumor Suppressors, SHIP and Rb, in Immune Suppressive Cells

Ruiz, C. G., & Marie, M. (2012)

Hormone-Sensitive Lipase - New roles in adipose tissue biology

Ström, K. (2008) · Lund University Publications (Lund University)

Fighting fat with fat: brown adipose tissue

Panda, S., & Mangaraj, M. (2014)

Identification of TRPV4 as a Regulator of Adipose Oxidative Metabolism, Inflammation and Energy Homeostasis by a Chemical Biology Approach

Li, Y. (2013) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Analytical strategies for identifying relevant phenotypes in microarray data

Wennmalm, K. (2007) · Figshare

Nrg4 and Gpr120 signalling in brown fat

Okolo, A. (2015) · doi:10.25560/26287

© 2012 Landes Bioscience. Do not distribute. Brown adipose tissue Recent insights into development, metabolic function and therapeutic potential

Townsend, K. L., & Tseng, Y. (2012)

Evidence of Browning Phenomenon and Its Physiological Relevance in Non-Adipose TissuesPreprint

Ho, D. H.-H., Moola, M. R., Lung, H. L., Yau, K.-H., Chan, H. Y.-S., Yuen, S.-N., Yue, P. Y., & Wong, R. H.-F. (2019) · SSRN Electronic Journal · doi:10.2139/ssrn.3363905

Regulation of PPARgamma2 Gene Expression by PcG AND pRb Family Proteins in the Course of Adipogenic Differentation of Mesenchymal Stem Cells

Ryabov, V., Vereshchagina, N. A., Ns, P., Litvinova, M. V., & Popov, B. V. (2021) · Cell and Tissue Biology · doi:10.1134/s1990519x2103010x

Faculty Opinions recommendation of Adaptive thermogenesis in adipocytes: is beige the new brown?

Symonds, M. E. (2013) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717979561.793471365

Estudi de l’expressió i funció del gen SIRT3 en el teixit adipós marró

Coll, A. G. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Rôle de E2F1 dans la sécrétion d'insuline, le métabolisme oxydatif, la néoglucogenèse et la lipogenèse. Implication dans le diabète, la dystrophie musculaire et le cancer

Blanchet, É. (2011) · theses.fr (ABES) · doi:10.70675/cf9df440zf3faz43bezb940z28698183447d

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Inhibition of p107 alleviates liver steatosis by reducing de novo fatty acid synthesisPreprint

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Brown Adipose Tissue: Molecular Mechanisms of Regulation, Physiological Functions, and Therapeutic Targets

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Role of Tyk2 in the Development of Beige Cells

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Histone acetylation modulates uncoupling protein1 expression in brown adipocytes

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Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation

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