Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

Kubota, Tetsuya, Kubota, Naoto, Kumagai, Hiroki, Yamaguchi, Shinichi, Kozono, Hideki, Takahashi, Takehiro, Inoue, Mariko, Itoh, Shinsuke +30 more·2011·Cell Metabolism
DOI 10.1016/j.cmet.2011.01.018

Cited by (435)

Items 101–200 of 435

  1. Perivascular Fat and the Microcirculation: Relevance to Insulin Resistance, Diabetes, and Cardiovascular Disease
    Alfons J.H.M. Houben, Etto C. Eringa, Amy M. Jonk, Erik H. Serné, Yvo Michiel Smulders, Coen D.A. Stehouwer · 2011 · Current Cardiovascular Risk Reports
  2. Muscle microvasculature's structural and functional specializations facilitate muscle metabolism
    Yvo H. A. M. Kusters, Eugene J. Barrett · 2015 · American Journal of Physiology-Endocrinology and Metabolism
  3. Super‐Resolution Ultrasound Imaging of Skeletal Muscle Microvascular Dysfunction in an Animal Model of Type 2 Diabetes
    Debabrata Ghosh, Jun Peng, Katherine Brown, Shashank Ramesh Sirsi, Chieko Mineo, Philip W. Shaul, Kenneth Hoyt · 2019 · Journal of Ultrasound in Medicine
  4. Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes
    Haaglim Cho, Chien-Cheng Lai, Rémy Bonnavion, Mohamad Wessam Alnouri, Shengpeng Wang, Kenneth Anthony Roquid, Haruya Kawase, Diana Campos, Min Chen, Lee Scott Weinstein et al. · 2025 · Science
  5. Fanconi Anemia Links Reactive Oxygen Species to Insulin Resistance and Obesity
    Jie Li, Jared Sipple, Suzette Maynard, Parinda A. Mehta, Susan Rogers Rose, Stella M. Davies, Qishen Pang · 2012 · Antioxidants and Redox Signaling
  6. Obesity, type 2 diabetes, and impaired insulin-stimulated blood flow: role of skeletal muscle NO synthase and endothelin-1
    Leryn J. Reynolds, Daniel Paul Credeur, Camila Margarita Manrique, Jaume Padilla, Paul J. Fadel, John P. Thyfault · 2016 · Journal of Applied Physiology
  7. N-glycans as functional effectors of genetic and epigenetic disease risk
    Tamara Štambuk, Marija Klasić, Vlatka Zoldoš, Gordan Lauc · 2020 · Molecular Aspects of Medicine
  8. The Endothelium: An Active Regulator of Lipid and Glucose Homeostasis
    Sana Safatul Hasan, Andreas Fischer · 2020 · Trends in Cell Biology
  9. Serine Phosphorylation Sites on IRS2 Activated by Angiotensin II and Protein Kinase C To Induce Selective Insulin Resistance in Endothelial Cells
    Kyoungmin Park, Qian Li, Christian Rask‐Madsen, Akira Mima, Koji Mizutani, Jonathon N. Winnay, Yasutaka Maeda, Katharine E. D’Aquino, Morris F. White, Edward P. Feener et al. · 2013 · Molecular and Cellular Biology
  10. SIRT1 attenuates high glucose-induced insulin resistance via reducing mitochondrial dysfunction in skeletal muscle cells
    Haohao Zhang, Xiaojun Ma, Lina Wu, Yanyan Zhao, Peng-Yu Zhang, Yinghui Zhang, Mingwei Shao, Fei Liu, Fei Li, Gui-Jun Qin · 2015 · Experimental Biology and Medicine
  11. Home‐hit improves muscle capillarisation and eNOS/NAD(P)Hoxidase protein ratio in obese individuals with elevated cardiovascular disease risk
    Sam N. Scott, Sam O. Shepherd, Nicola D. Hopkins, Ellen A. Dawson, Juliette A. Strauss, David Justin Wright, Robert G Cooper, Pradesh Kumar, Anton J. M. Wagenmakers, Matthew S. Cocks · 2019 · The Journal of Physiology
  12. Vascular dysfunction as a potential culprit of sarcopenia
    Jeon, Yun Kyung, Shin, Myung Jun, Saini, Sunil Kumar, Custodero, Carlo, Aggarwal, Monica, Anton, Stephen D., Leeuwenburgh, Christiaan, Mankowski, Robert T. · 2021 · Experimental Gerontology
  13. Intercellular Communication Lessons in Heart Failure
    Claudia Bang, Charalambos A. Antoniades, Alexios S. Antonopoulos, Ulf Eriksson, Constantijn Franssen, Nazha Hamdani, Lorenz Lehmann, Christine Moessinger, Marco Mongillo, Lars Muhl et al. · 2015 · European Journal of Heart Failure
  14. Insulin decreases atherosclerosis by inducing endothelin receptor B expression
    Kyoungmin Park, Akira Mima, Qian Li, Christian Rask‐Madsen, Pingnian He, Koji Mizutani, Sayaka Katagiri, Yasutaka Maeda, I‐Hsien Wu, Mogher Khamaisi et al. · 2016 · JCI Insight
  15. Ischemia reperfusion-facilitated sinusoidal endothelial cell injury in liver transplantation and the resulting impact of extravasated platelet aggregation
    Tomoharu Miyashita, Shinichi Nakanuma, Ali Karim Ahmed, Isamu Makino, Hironori Hayashi, Katsunobu Oyama, Hisatoshi Nakagawara, Hidehiro Tajima, Hiroyuki Takamura, Itasu Ninomiya et al. · 2015 · European surgery. Supplement/European surgery
  16. The role of cardiac lipotoxicity in the pathogenesis of diabetic cardiomyopathy
    John R. Ussher · 2014 · Expert Review of Cardiovascular Therapy
  17. Toll-like receptor 4-induced endoplasmic reticulum stress contributes to impairment of vasodilator action of insulin.
    Jeong-a Kim, H. Jang, D. Hwang · 2015 · American Journal of Physiology. Endocrinology and Metabolism
  18. Bone morphogenetic protein‐7 (BMP‐7) augments insulin sensitivity in mice with type II diabetes mellitus by potentiating PI3K/AKT pathway
    Tandrika Chattopadhyay, Rajiv Ranjan Singh, Sarika Gupta, Avadhesha Surolia · 2017 · BioFactors
  19. Diabetes pathogenesis and management: the endothelium comes of age
    Kaitlin M. Love, Eugene J. Barrett, Steven K. Malin, Jane E.B. Reusch, Judith G. Regensteiner, Zhenqi Liu · 2021 · Journal of Molecular Cell Biology
  20. Molecular basis of insulin resistance: the role of IRS and Foxo1 in the control of diabetes mellitus and its complications
    Shaodong Guo · 2013 · Drug Discovery Today Disease Mechanisms
  21. Brg1 deficiency in vascular endothelial cells blocks neutrophil recruitment and ameliorates cardiac ischemia-reperfusion injury in mice
    Xinjian Zhang, Shuai Liu, Xinyu Weng, Sheng Zeng, Liming Yu, Junli Guo, Yong Xu · 2018 · International Journal of Cardiology
  22. Increased skeletal muscle capillarization enhances insulin sensitivity
    Akerstrom, Thorbjorn, Laub, Lasse, Vedel, Kenneth, Brand, Christian Lehn, Pedersen, Bente Klarlund, Lindqvist, Anna Kaufmann, Wojtaszewski, Jørgen F. P., Hellsten, Ylva · 2014 · American Journal of Physiology-Endocrinology and Metabolism
  23. The endothelium in diabetes: Its role in insulin access and diabetic complications
    Cathryn M. Kolka, Richard N. Bergman · 2013 · Reviews in Endocrine and Metabolic Disorders
  24. Common metabolic features of hypertension and type 2 diabetes
    Isao Usui · 2023 · Hypertension Research
  25. C-Reactive Protein Causes Insulin Resistance in Mice Through Fcγ Receptor IIB–Mediated Inhibition of Skeletal Muscle Glucose Delivery
    Keiji Tanigaki, Wanpen Vongpatanasin, Jose A. Barrera, Dmitriy N. Atochin, Paul Lee Huang, Ezio Bonvini, Philip W. Shaul, Chieko Mineo · 2012 · Diabetes
  26. Relaxin Treatment Reverses Insulin Resistance in Mice Fed a High-Fat Diet
    Bonner, Jeffrey S., Lantier, Louise, Hocking, Kyle M., Kang, Li, Owolabi, Mark, James, Freyja D., Bracy, Deanna P., Brophy, Colleen M., Wasserman, David H. · 2013 · Diabetes
  27. G Protein–Coupled Receptor Kinase 2, With β-Arrestin 2, Impairs Insulin-Induced Akt/Endothelial Nitric Oxide Synthase Signaling in ob/ob Mouse Aorta
    Kumiko Taguchi, Takayuki Matsumoto, Katsuo Kamata, Tsuneo Kobayashi · 2012 · Diabetes
  28. Unexpected Pleiotropic Effects of SGLT2 Inhibitors: Pearls and Pitfalls of This Novel Antidiabetic Class
    Hideaki Kaneto, Atsushi Obata, Tomohiko Kimura, Masashi Shimoda, Tomoe Kinoshita, Taka‐aki Matsuoka, Kohei Kaku · 2021 · International Journal of Molecular Sciences
  29. Unraveling Skeletal Muscle Insulin Resistance: Molecular Mechanisms and the Restorative Role of Exercise
    Katie L. Whytock, Bret H. Goodpaster · 2025 · Circulation Research
  30. Correlated mRNAs and miRNAs from co-expression and regulatory networks affect porcine muscle and finally meat properties
    Siriluck Ponsuksili, Yang Du, Frieder Hadlich, Puntita Siengdee, Eduard Muráni, M. Schwerin, Klaus Wimmers · 2013 · BMC Genomics
  31. Insulin exits skeletal muscle capillaries by fluid-phase transport
    Ian M. Williams, Francisco A. Valenzuela, Steven D. Kahl, Doraiswami Ramkrishna, Adam R. Mezo, Jamey D. Young, K. Sam Wells, David H. Wasserman · 2018 · Journal of Clinical Investigation
  32. Insulin Receptor Substrate-2 (Irs2) in Endothelial Cells Plays a Crucial Role in Insulin Secretion
    Shinji Hashimoto, Naoto Kubota, Hiroyuki Satō, Motohiro Sasaki, Iseki Takamoto, Tetsuya Kubota, Keizo Nakaya, Mitsuhiko Noda, Kohjiro Ueki, Takashi Kadowaki · 2014 · Diabetes
  33. Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulin.
    H. Jang, Hae-Su Kim, D. Hwang, M. Quon, Jeong-a Kim · 2013 · American Journal of Physiology. Endocrinology and Metabolism
  34. Matrix metalloproteinase 9 opposes diet-induced muscle insulin resistance in mice
    Kang, Li, Mayes, Wesley H., James, Freyja D., Bracy, Deanna P., Wasserman, David H. · 2014 · Diabetologia
  35. Class II transactivator (CIITA) mediates IFN-γ induced eNOS repression by enlisting SUV39H1
    Xinyu Weng, Yuanyuan Zhang, Zilong Li, Liming Yu, Feng Xu, Mingming Fang, Lei Hou, Junbo Ge, Yong Xu · 2019 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  36. Adipocyte-Endothelium Crosstalk in Obesity
    Rugivan Sabaratnam, Per Svenningsen · 2021 · Frontiers in Endocrinology
  37. Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop
    Viswambharan, Hema, Yuldasheva, Nadira Y., Sengupta, Anshuman, Imrie, Helen, Gage, Matthew C., Haywood, Natalie, Walker, Andrew M.N., Skromna, Anna, Makova, Natallia, Galloway, Stacey et al. · 2017 · Circulation Research
  38. Insulin signalling to the kidney in health and disease
    Lorna J. Hale, Richard J. Coward · 2012 · Clinical Science
  39. Targeting the vasculature in cardiometabolic disease
    Nabil E. Boutagy, Abhishek K. Singh, William C. Sessa · 2022 · Journal of Clinical Investigation
  40. The role of endothelial insulin signaling in the regulation of glucose metabolism
    Tetsuya Kubota, Naoto Kubota, Takashi Kadowaki · 2013 · Reviews in Endocrine and Metabolic Disorders
  41. Exercise-Induced Signals for Vascular Endothelial Adaptations: Implications for Cardiovascular Disease
    Nathan T. Jenkins, Jeffrey S. Martin, M. Harold Laughlin, Jaume Padilla · 2012 · Current Cardiovascular Risk Reports
  42. Muscle insulin resistance resulting from impaired microvascular insulin sensitivity in Sprague Dawley rats
    Dino Premilovac, Eloise A. Bradley, Huei Ng, Stephen Michael Richards, Stephen Rattigan, Michelle A. Keske · 2013 · Cardiovascular Research
  43. Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2
    Joana Moitinho Oliveira, Sandra A. Rebuffat, Rosa Gasa, Ramón Gomis · 2014 · Canadian Journal of Physiology and Pharmacology
  44. Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells
    Ping Zhao, Di Tian, Guanjun Song, Qian Zhong Ming, Jia Liu, Jinhua Shen, Qinghua Liu, Xinzhou Yang · 2019 · Frontiers in Pharmacology
  45. The Postprandial Appearance of Features of Cardiometabolic Risk: Acute Induction and Prevention by Nutrients and Other Dietary Substances
    Dimina, Laurianne, Mariotti, François · 2019 · Nutrients
  46. Prokineticin Receptor‐1 Is a New Regulator of Endothelial Insulin Uptake and Capillary Formation to Control Insulin Sensitivity and Cardiovascular and Kidney Functions
    Mojdeh Dormishian, Gülen Türkeri, Kyoji Urayama, Thu Lan Nguyen, Mounia Boulberdaa, Nadia Messaddeq, Gilles Renault, Daniel Henrion, Canan G. Nebigil · 2013 · Journal of the American Heart Association
  47. VEGF‐B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content
    Christine Moessinger, Ingrid Nilsson, Lars Muhl, Manuel Zeitelhofer, Benjamin Heller Sahlgren, Josefin Skogsberg, Ulf Eriksson · 2020 · EMBO Reports
  48. Impaired Delivery of Insulin to Adipose Tissue and Skeletal Muscle in Obese Women with Postprandial Hyperglycemia
    Sandqvist, M., Strindberg, L., Schmelz, M., Lönnroth, P., Jansson, P.-A. · 2011 · The Journal of Clinical Endocrinology & Metabolism
  49. Sildenafil Increases Muscle Protein Synthesis and Reduces Muscle Fatigue
    Melinda Sheffield‐Moore, John E. Wiktorowicz, Kizhake V. Soman, Christopher P. Danesi, Michael P. Kinsky, E. Lichar Dillon, Kathleen M. Randolph, Shanon L. Casperson, Dennis C. Gore, Astrid M. H. Horstman et al. · 2013 · Clinical and Translational Science
  50. Teneligliptin: expectations for its pleiotropic action
    Ryuichi Morishita, Hironori Nakagami · 2015 · Expert Opinion on Pharmacotherapy
  51. A Three-phase Approach for the Early Identification of Acute Lung Injury Induced by Severe Sepsis.
    Tomoharu Miyashita, Ali Karim Ahmed, Shinichi Nakanuma, Koichi Okamoto, Seisho Sakai, Jun Kinoshita, Isamu Makino, Keishi Nakamura, Hironori Hayashi, Katsunobu Oyama et al. · 2016 · PubMed
  52. Endothelial TFEB (Transcription Factor EB) Improves Glucose Tolerance via Upregulation of IRS (Insulin Receptor Substrate) 1 and IRS2
    Jinjian Sun, Haocheng Lu, Wenying Liang, Guizhen Zhao, Lü Ren, Die Hu, Ziyi Chang, Yuhao Liu, Minerva T. Garcia-Barrio, Jifeng Zhang et al. · 2020 · Arteriosclerosis Thrombosis and Vascular Biology
  53. (Pro)renin receptor in skeletal muscle is involved in the development of insulin resistance associated with postinfarct heart failure in mice
    Arata Fukushima, Shintaro Kinugawa, Shingo Takada, Shouji Matsushima, Mochamad Ali Sobirin, Taisuke Ono, Masashige Takahashi, Tadashi Suga, Tsuneaki Homma, Yoshihiro Masaki et al. · 2014 · American Journal of Physiology-Endocrinology and Metabolism
  54. Endothelial Transcytosis of Insulin: Does It Contribute to Insulin Resistance?
    Warren L. Lee, Amira Klip · 2016 · Physiology
  55. Local NOS inhibition impairs vascular and metabolic actions of insulin in rat hindleg muscle in vivo
    Eloise A. Bradley, Stephen Michael Richards, Michelle A. Keske, Stephen Rattigan · 2013 · American Journal of Physiology-Endocrinology and Metabolism
  56. Role of habitual physical activity in modulating vascular actions of insulin
    Jaume Padilla, T. Dylan Olver, John P. Thyfault, Paul J. Fadel · 2015 · Experimental Physiology
  57. Insulin uptake and action in microvascular endothelial cells of lymphatic and blood origin
    Javier R. Jaldín‐Fincati, Rafaela Vaz Sousa Pereira, Philip J. Bilan, Amira Klip · 2018 · American Journal of Physiology-Endocrinology and Metabolism
  58. Molecular Insights of MAP4K4 Signaling in Inflammatory and Malignant Diseases
    Sunil Kumar Singh, Ruchi Roy, Sandeep Kumar, Piush Srivastava, Saket Jha, Basabi Rana, Ajay Rana · 2023 · Cancers
  59. Ecscr regulates insulin sensitivity and predisposition to obesity by modulating endothelial cell functions
    Yoshiki Akakabe, Masahiro Koide, Youhei Kitamura, Kiyonari Matsuo, Tomomi Ueyama, Satoaki Matoba, Hiroyuki Yamada, Keishi Miyata, Yuichi Oike, Koji Ikeda · 2013 · Nature Communications
  60. trans ‐ferulic acid attenuates hyperglycemia‐induced oxidative stress and modulates glucose metabolism by activating AMPK signaling pathway in vitro
    Sangeetha S. B. Singh, K. Neelakanteshwar Patil · 2022 · Journal of Food Biochemistry
  61. Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
    Wineke Bakker, Mónica Imbernón, Casper Gravesen Salinas, Daniela Herrera Moro Chao, Rim Hassouna, Chloe Morel, Claire Martin, Caroline Leger, R Denis, Julien Castel et al. · 2022 · Cell Reports
  62. Relationship Between Glucocorticoids and Insulin Resistance in Healthy Individuals
    Peng-Zhen Zhou, Yongmei Zhu, Guang-Hui Zou, Yuxia Sun, Xian Xiu, Xin Yi Huang, Qunhui Zhang · 2016 · Medical Science Monitor
  63. PPAR β activation restores the high glucose‐induced impairment of insulin signalling in endothelial cells
    Ana María Quintela, Rosario Jiménez, Laura Piqueras, Manuel Gómez‐Guzmán, J Haro, María José Zarzuelo-Romero, Angel L. Cogolludo, María‐Jesús Sanz, Marta Toral, Miguel Romero et al. · 2014 · British Journal of Pharmacology
  64. Deletion of TXNIP Mitigates High-Fat Diet-Impaired Angiogenesis and Prevents Inflammation in a Mouse Model of Critical Limb Ischemia
    Sally L. Elshaer, Islam Mohamed, Maha M Coucha, Sara Altantawi, Wael Eldahshan, Megan Bartasi, Ahmed Y. Shanab, Renee Lorys, Azza B. El‐Remessy · 2017 · Antioxidants
  65. Liver Sinusoidal Endothelial Cells Link Hyperinsulinemia to Hepatic Insulin Resistance
    Kyoichiro Tsuchiya, Domenico Accili · 2013 · Diabetes
  66. The dipeptidyl peptidase-4 inhibitor teneligliptin improved endothelial dysfunction and insulin resistance in the SHR/NDmcr-cp rat model of metabolic syndrome
    Hironori Nakagami, Zheng‐Da Pang, Takashi Shimosato, Toshinori Moritani, Hitomi Kurinami, Hiroshi Koriyama, Akiko Tenma, Munehisa Shimamura, Ryuichi Morishita · 2014 · Hypertension Research
  67. Dietary Isoliquiritigenin at a Low Dose Ameliorates Insulin Resistance and NAFLD in Diet-Induced Obesity in C57BL/6J Mice
    Young‐Mi Lee, Eun‐Young Kwon, Myung‐Sook Choi · 2018 · International Journal of Molecular Sciences
  68. Skeletal Muscle Microvascular Dysfunction in Obesity-Related Insulin Resistance: Pathophysiological Mechanisms and Therapeutic Perspectives
    Chiedozie Kenneth Ugwoke, Erika Cvetko, Nejc Umek · 2022 · International Journal of Molecular Sciences
  69. Low apoA-I is associated with insulin resistance in patients with impaired glucose tolerance: a cross-sectional study
    Xiaomeng Feng, Xia Gao, Zhi Jian Yao, Yuan Xu · 2017 · Lipids in Health and Disease
  70. Insulin Regulation of Myocardial Autophagy
    Christian Riehle, E. Dale Abel · 2014 · Circulation Journal
  71. Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase–Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance
    Nicole T. Watt, Matthew Gage, Peysh A Patel, Hema Viswambharan, Piruthivi Sukumar, Stacey L. Galloway, Nadira Y. Yuldasheva, Helen Imrie, Andrew MN Walker, Kathryn Jane Griffin et al. · 2017 · Diabetes
  72. Semi-automatic assessment of skin capillary density: Proof of principle and validation
    E. H. B. M. Gronenschild, Dennis M.J. Muris, Miranda T. Schram, Ü. Karaca, Coen D.A. Stehouwer, Alfons J.H.M. Houben · 2013 · Microvascular Research
  73. Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: A randomised controlled trial
    van Raalte, Daniël H., Diamant, Michaela, Ouwens, D. Margriet, Ijzerman, Richard G., Linssen, Margot M. L., Guigas, Bruno, Eringa, Etto C., Serné, Erik H. · 2013 · Diabetologia
  74. A vascular mechanism for high-sodium-induced insulin resistance in rats
    Dino Premilovac, Stephen Michael Richards, Stephen Rattigan, Michelle A. Keske · 2014 · Diabetologia
  75. Long-term high-fructose high-fat diet feeding elicits insulin resistance, exacerbates dyslipidemia and induces gut microbiota dysbiosis in WHHL rabbits
    Michelle Moughaizel, Elie Dagher, Amin Jablaoui, Chantal Thorin, Moez Rhimi, Jean‐Claude Desfontis, Yassine Mallem · 2022 · PLoS ONE
  76. The effect of different training modes on skeletal muscle microvascular density and endothelial enzymes controlling NO availability
    Matthew S. Cocks, Anton J. M. Wagenmakers · 2015 · The Journal of Physiology
  77. The Endothelium Abridges Insulin Resistance to Premature Aging
    Angelo Avogaro, Saula Vigili de Kreutzenberg, Massimo Federici, Gian Paolo Fadini · 2013 · Journal of the American Heart Association
  78. Endothelial metabolic control of insulin sensitivity through resident macrophages
    Jing Zhang, Kim Anker Sjøberg, Songlin Gong, Tongtong Wang, Fengqi Li, Andrew Kuo, Stephan Durot, Adam Majcher, Raphaela Ardicoglu, Thibaut Desgeorges et al. · 2024 · Cell Metabolism
  79. New insights into mechanisms of endothelial insulin resistance in type 2 diabetes
    Jaume Padilla, Camila Manrique‐Acevedo, Luis Arturo Martinez‐Lemus · 2022 · American Journal of Physiology-Heart and Circulatory Physiology
  80. Caveolin-1 phosphorylation regulates vascular endothelial insulin uptake and is impaired by insulin resistance in rats
    Hong Wang, Aileen X. Wang, Kevin W. Aylor, Eugene J. Barrett · 2015 · Diabetologia
  81. Vascular Endothelial Regulation of Obesity-Associated Insulin Resistance
    Manna Li, Ming Qian, Jian Xu · 2017 · Frontiers in Cardiovascular Medicine
  82. Identification of Common Regulators of Genes in Co-Expression Networks Affecting Muscle and Meat Properties
    Siriluck Ponsuksili, Puntita Siengdee, Yang Du, Nares Trakooljul, Eduard Muráni, M. Schwerin, Klaus Wimmers · 2015 · PLoS ONE
  83. Free fatty acid-induced H2O2 activates TRPM2 to aggravate endothelial insulin resistance via Ca2+-dependent PERK/ATF4/TRB3 cascade in obese mice
    Lu Sun, Yanli Liu, Fang Ye, Jingwen Xie, Jiawei Zeng, Qin Li, Jing Xue, Yi-Ting Wang, Kai-Min Guo, Ming-Ming Ma et al. · 2019 · Free Radical Biology and Medicine
  84. Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites
    Susana Cavallero, Mehrdad Roustaei, Sandro Satta, Jae Min Cho, Henry Phan, Kyung In Baek, Ana M. Blázquez‐Medela, Sheila Gonzalez-Ramos, Khoa Vu, Seulki Park et al. · 2024 · Science Advances
  85. Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPKα2
    Michiel P. de Boer, Rick I. Meijer, Erik Arne Richter, Geerten P. van Nieuw Amerongen, P. Sipkema, Erik M. van Poelgeest, Jurjan Aman, Tom J. A. Kokhuis, Pieter Koolwijk, Victor W.M. van Hinsbergh et al. · 2015 · Vascular Pharmacology
  86. Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells
    Norihiko Sasaki, Yoko Itakura, Masashi Toyoda · 2015 · Journal of Biological Chemistry
  87. Regulation of microvascular flow and metabolism: An overview
    Michelle A. Keske, Renee M Dwyer, Ryan Russell, Sarah Joan Blackwood, Aascha A. Brown, Donghua Hu, Dino Premilovac, Stephen Michael Richards, Stephen Rattigan · 2016 · Clinical and Experimental Pharmacology and Physiology
  88. Vascular endothelial PDPK1 plays a pivotal role in the maintenance of pancreatic beta cell mass and function in adult male mice
    Atsushi Obata, Tomohiko Kimura, Yoshiyuki Obata, Masashi Shimoda, Tomoe Kinoshita, Kenji Kohara, Seizo Okauchi, Hidenori Hirukawa, Shinji Kamei, Shuhei Nakanishi et al. · 2019 · Diabetologia
  89. Capillary Endothelial Insulin Transport: The Rate-limiting Step for Insulin-stimulated Glucose Uptake
    Ian M. Williams, David H. Wasserman · 2021 · Endocrinology
  90. Insulin‐Induced Changes in Microvascular Vasomotion and Capillary Recruitment are Associated in Humans
    Michiel P. de Boer, Rick I. Meijer, John Newman, Coen D.A. Stehouwer, Etto C. Eringa, Yvo Michiel Smulders, Erik H. Serné · 2014 · Microcirculation
  91. IgG Receptor FcγRIIB Plays a Key Role in Obesity-Induced Hypertension
    Nathan C. Sundgren, Wanpen Vongpatanasin, Brigid Boggan, Keiji Tanigaki, Ivan S. Yuhanna, Ken L. Chambliss, Chieko Mineo, Philip W. Shaul · 2014 · Hypertension
  92. Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice
    Keiji Tanigaki, Ken L. Chambliss, Ivan S. Yuhanna, Anastasia Sacharidou, Mohamed H. Ahmed, Dmitriy N. Atochin, Paul Lee Huang, Philip W. Shaul, Chieko Mineo · 2016 · Diabetes
  93. Prokineticin Is a New Linker between Obesity and Cardiovascular Diseases
    Canan G. Nebigil · 2017 · Frontiers in Cardiovascular Medicine
  94. Angiogenesis in metabolic-vascular disease
    Georg Breier, Triantafyllos Chavakis, Emilio Hirsch · 2017 · Thrombosis and Haemostasis
  95. High-Fat Overfeeding Impairs Peripheral Glucose Metabolism and Muscle Microvascular eNOS Ser1177 Phosphorylation
    Sion A. Parry, Mark C. Turner, Rachel M. Woods, Lewis John James, Richard A. Ferguson, Matthew S. Cocks, Katie L. Whytock, Juliette A. Strauss, Sam O. Shepherd, Anton J. M. Wagenmakers et al. · 2019 · The Journal of Clinical Endocrinology & Metabolism
  96. Role of platelet-derived growth factor c on endothelial dysfunction in cardiovascular diseases
    Adriana Grismaldo, Luis Sobrevía, Ludis Morales · 2022 · Biochimica et Biophysica Acta (BBA) - General Subjects
  97. Is vascular insulin resistance an early step in diet-induced whole-body insulin resistance?
    Lauren Carmichael, Michelle A. Keske, Andrew C. Betik, Lewan Parker, Bárbara Brayner, Katherine M. Roberts‐Thomson, Glenn David Wadley, David Lee Hamilton, Gunveen Kaur · 2022 · Nutrition and Diabetes
  98. Fine particulate matter (PM2.5)-induced pulmonary oxidative stress contributes to increases in glucose intolerance and insulin resistance in a mouse model of circadian dyssynchrony
    Amanda Ribble, Jason L. Hellmann, Daniel J. Conklin, Aruni Bhatnagar, Petra Haberzettl · 2023 · The Science of The Total Environment
  99. Endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle
    Sacharidou, Anastasia, Chambliss, Ken, Peng, Jun, Barrera, Jose, Tanigaki, Keiji, Luby-Phelps, Katherine, Özdemir, İpek, Khan, Sohaib, Sirsi, Shashank R., Kim, Sung Hoon et al. · 2023 · Nature Communications
  100. Antiobesogenic Role of Endothelial Nitric Oxide Synthase
    Brian E. Sansbury, Bradford G. Hill · 2014 · Vitamins and hormones