MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells

Sancho, Patricia, Burgos-Ramos, Emma, Tavera, Alejandra, Bou Kheir, Tony, Jagust, Petra, Schoenhals, Matthieu, Barneda, David, Sellers, Katherine +6 more·2015·Cell Metabolism

Cited by (728)

Items 101–200 of 728

  1. The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes
    Fan Xing, Yizhao Luan, Jing Cai, Sihan Wu, Jialuo Mai, Jiayu Gu, Haipeng Zhang, Kai Li, Yuan Lin, Xiao Xiao et al. · 2017 · Cell Reports
  2. Redox regulation of cell state and fate
    Bernice Woon Li Lee, Pramila Baban Ghode, Derrick Sek Tong Ong · 2018 · Redox Biology
  3. The metabolic modulator PGC-1α in cancer.
    Frédéric Bost, Lisa Kaminski · 2019 · Europe PMC (PubMed Central)
  4. Target c-Myc to treat pancreatic cancer
    Moein Ala · 2022 · Cancer Biology & Therapy
  5. Redox signaling at the crossroads of human health and disease
    Jing Zuo, Zhe Zhang, Maochao Luo, Li Zhou, Edouard Collins Nice, Wei Zhang, Chuang Wang, Canhua Huang · 2022 · MedComm
  6. The Effect of Oxidative Phosphorylation on Cancer Drug Resistance
    Zi-Yi Zhao, Yong Mei, Ziyang Wang, Weiling He · 2022 · Cancers
  7. Energy disruptors: rising stars in anticancer therapy?
    Frédéric Bost, A.G. Poullot, Jean‐François Tanti, Stéphan Clavel · 2016 · Oncogenesis
  8. Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma
    Consuelo Torrini, Trang Thi Thu Nguyen, Chang Shu, Angeliki Mela, Nelson Humala, Aayushi Mahajan, E. Seeley, Guoan Zhang, Mike‐Andrew Westhoff, Georg Karpel‐Massler et al. · 2022 · Molecular Cell
  9. Unraveling the journey of cancer stem cells from origin to metastasis
    Rama Krishna Nimmakayala, Surinder K. Batra, Moorthy Palanimuthu Ponnusamy · 2018 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  10. DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster
    Sladjana Zagorac, Sonia Alcalá, Gustavo F. Bayón, Tony Bou Kheir, Matthieu J. Schoenhals, Anna González‐Neira, Mario F. Fraga, Alexandra Aicher, Christopher Heeschen, Bruno Sáinz · 2016 · Cancer Research
  11. PGC-1 Coactivators: Shepherding the Mitochondrial Biogenesis of Tumors
    Chi Luo, Hans R. Widlund, Pere Puigserver · 2016 · Trends in cancer
  12. The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies
    Btissame El Hassouni, Carlotta Granchi, Andrea Vallés‐Martí, I Gede Putu Supadmanaba, Giulia Bononi, Tiziano Tuccinardi, Niccola Funel, Connie R. Jiménez, Godefridus J. Peters, Elisa Giovannetti et al. · 2019 · Seminars in Cancer Biology
  13. Pancreatic cancer stem cells: features and detection methods
    Toshiyuki Ishiwata, Yoko Matsuda, Hisashi Yoshimura, Norihiko Sasaki, Shunji Ishiwata, Naoshi Ishikawa, Kaiyo Takubo, Tomio Arai, Junko Aida · 2018 · Pathology & Oncology Research
  14. Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells
    Genini, Davide, Brambilla, Lara, Laurini, Erik, Merulla, Jessica, Civenni, Gianluca, Pandit, Shusil, D'Antuono, Rocco, Perez, Laurent, Levy, David E., Pricl, Sabrina et al. · 2017 · Proceedings of the National Academy of Sciences
  15. Role of Mitochondria in Cancer Stem Cell Resistance
    J. M. García-Heredia, A. Carnero · 2020 · Cells
  16. ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells
    Ching-Wen Chang, Yu−Syuan Chen, Yeou‐Guang Tsay, Chia‐Li Han, Yu‐Ju Chen, Cheng-Chieh Yang, Kai-Feng Hung, Chao‐Hsiung Lin, Tsung-Yen Huang, Shou‐Yen Kao et al. · 2018 · Cell Death and Disease
  17. Therapeutic Strategies Targeting Cancer Stem Cells and Their Microenvironment
    Haoran Sun, Shun Li Wang, Shican Yan, Yu Zhang, Peter Jon Nelson, Hu‐Liang Jia, Lun–Xiu Qin, Qiongzhu Dong · 2019 · Frontiers in Oncology
  18. Reactive oxygen species produced by altered tumor metabolism impacts cancer stem cell maintenance
    Kaysaw Tuy, Lucas Rickenbacker, Anita B. Hjelmeland · 2021 · Redox Biology
  19. Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM)
    Ronald C. Bruntz, Andrew N. Lane, Richard M. Higashi, Teresa W.‐M. Fan · 2017 · Journal of Biological Chemistry
  20. Cancer resistance and metastasis are maintained through oxidative phosphorylation
    Cemile Uslu, Eda Kapan, Alex Lyakhovich · 2024 · Cancer Letters
  21. Pancreatic cancer: Current research and future directions
    Marco Falasca, Minkyoung Kim, Ilaria Casari · 2016 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  22. FoxM1-dependent and fatty acid oxidation-mediated ROS modulation is a cell-intrinsic drug resistance mechanism in cancer stem-like cells
    Hae-Ji Choi, Yoo-Lim Jhe, Jungmin Kim, Ju Yeon Lim, Jae Eun Lee, Min‐Kyue Shin, Jae‐Ho Cheong · 2020 · Redox Biology
  23. EMT and Stemness—Key Players in Pancreatic Cancer Stem Cells
    E. Rodríguez-Aznar, L. Wiesmüller, B. Sainz, P. Hermann · 2019 · Cancers
  24. Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping
    Rosemary Lane, Thomas Simon, Marian Vintu, Benjamin Solkin, Barbara Koch, Nicolas Andre Stewart, Graeme Benstead-Hume, Frances M. G. Pearl, Giles R. Critchley, Justin Stebbing et al. · 2019 · Communications Biology
  25. Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program
    Esther Aguilar, Igor Marín de Mas, Erika Zodda, Silvia Marín, Fionnuala M. Morrish, Vitaly A. Selivanov, Óscar Meca‐Cortés, Hossain Delowar, Mònica Pons, Inés Izquierdo et al. · 2016 · Stem Cells
  26. Pancreatic cancer stem cells: A state or an entity?
    Patrick Christian Hermann, Bruno Sáinz · 2018 · Seminars in Cancer Biology
  27. Crosstalk between autophagy and metabolic regulation of cancer stem cells
    Mouradi El-Hout, Emma Cosialls, Maryam Mehrpour, Ahmed Hamaï · 2020 · Molecular Cancer
  28. Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics
    Alia Ghoneum, Ammar Yasser Abdulfattah, Bailey Warren, Junjun Shu, Neveen A. Said · 2020 · International Journal of Molecular Sciences
  29. Targeting LIN28B reprograms tumor glucose metabolism and acidic microenvironment to suppress cancer stemness and metastasis
    Chong Chen, Lipeng Bai, Fengqi Cao, Shengnan Wang, Huiwen He, Mingcheng Song, Huilin Chen, Yan Liu, Jian Guo, Qin Si et al. · 2019 · Oncogene
  30. Cancer stem cell (a)symmetry & plasticity: Tumorigenesis and therapy relevance
    Masoud Najafi, Keywan Mortezaee, Reza Ahadi · 2019 · Life Sciences
  31. Mitochondria as target to inhibit proliferation and induce apoptosis of cancer cells: the effects of doxycycline and gemcitabine
    Sas N. Dijk, Margherita Protasoni, Marilena Elpidorou, A.M. Kroon, Jan‐Willem Taanman · 2020 · Scientific Reports
  32. 3D Co-culture of Cancer-Associated Fibroblast with Oral Cancer Organoids
    Hui Zhao, Erhui Jiang, Z. Shang · 2020 · Journal of Dental Research
  33. Lessons Learned from Two Decades of Anticancer Drugs
    Zhichao Liu, Brian Delavan, Ruth Angela Roberts, Weida Tong · 2017 · Trends in Pharmacological Sciences
  34. PGC1α: Friend or Foe in Cancer?
    Francesca Mastropasqua, Giulia Girolimetti, Maria Caspar Shoshan · 2018 · Genes
  35. An Upstream Open Reading Frame in Phosphatase and Tensin Homolog Encodes a Circuit Breaker of Lactate Metabolism
    Nunu Huang, Fanying Li, Maolei Zhang, Huangkai Zhou, Zhipeng Chen, Xiaoyan Ma, Lixuan Yang, Xujia Wu, Jian Zhong, Feizhe Xiao et al. · 2021 · Cell Metabolism
  36. Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit
    Claudia R. Oliva, Wei Zhang, Cathy Langford, Mark J. Suto, Corinne E. Griguer · 2017 · Oncotarget
  37. Mitochondrial Dysfunction at the Center of Cancer Therapy
    Hsin Yao Chiu, Emmy Xue Yun Tay, Derrick Sek Tong Ong, Reshma Taneja · 2019 · Antioxidants and Redox Signaling
  38. Targeting cancer-cell mitochondria and metabolism to improve radiotherapy response
    Emma McCann, Jacintha N O'Sullivan, Simone Marcone · 2020 · Translational Oncology
  39. Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate
    Alejandro Vázquez‐Martín, Chris Van den Haute, Sílvia Cufí, Bruna Corominas-Faja, Elisabet Cuyàs, Eugeni López‐Bonet, Esther Rodríguez‐Gallego, Salvador Fernández‐Arroyo, Jorge Joven, Veerle Baekelandt et al. · 2016 · Aging
  40. The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer
    Yang‐An Wen, Xiaopeng Xiong, Timothy L. Scott, Austin T. Li, Chi Wang, Heidi L. Weiss, Li Tan, Emily M. Bradford, Teresa W.‐M. Fan, Navdeep S. Chandel et al. · 2019 · Cell Death and Differentiation
  41. Glycometabolic rearrangements--aerobic glycolysis in pancreatic cancer: causes, characteristics and clinical applications
    Lidong Cao, Jiacheng Wu, Xianzhi Qu, Jiyao Sheng, Mengying Cui, Shui Liu, Xu Huang, Yien Xiang, Bingjin Li, Xuewen Zhang et al. · 2020 · Journal of Experimental & Clinical Cancer Research
  42. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer
    Nadine S. Jahchan, Jing Shan Lim, Becky M. Bola, Karen L. Morris, Garrett Seitz, Kim Q.T. Tran, Lei Xu, Francesca Trapani, Christopher J. Morrow, Sandra Cristea et al. · 2016 · Cell Reports
  43. Concepts to Target MYC in Pancreatic Cancer
    Matthias Wirth, Siavosh Mahboobi, Oliver Holger Krämer, Günter Schneider · 2016 · Molecular Cancer Therapeutics
  44. Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation
    Yapeng Ji, Chuanzhen Yang, Zefang Tang, Yongfeng Yang, Yonglu Tian, Hongwei Yao, Xi De Zhu, Zemin Zhang, Jiafu Ji, Xiaofeng Zheng · 2017 · Nature Communications
  45. Sirtuin‐1/Mitochondrial Ribosomal Protein S5 Axis Enhances the Metabolic Flexibility of Liver Cancer Stem Cells
    Zhihao Wei, Jiankun Jia, Gang Heng, Huailong Xu, Juanjuan Shan, Guiqin Wang, Chungang Liu, Jianyu Xia, Haijun Zhou, Min Cong Wu et al. · 2019 · Hepatology
  46. Mitochondrial Metabolism in PDAC: From Better Knowledge to New Targeting Strategies
    Gabriela Reyes‐Castellanos, Rawand Masoud, Alice Carrier · 2020 · Biomedicines
  47. Targeting Cancer Stem Cell Redox Metabolism to Enhance Therapy Responses
    Ming Luo, Max S. Wicha · 2018 · Seminars in Radiation Oncology
  48. Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells
    Halbrook, Christopher J., Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A., McCarthy, Amy, Steele, Nina G., Kerk, Samuel A., Hong, Hanna S., Lin, Lin et al. · 2022 · Nature Cancer
  49. Metabolic traits of cancer stem cells
    Joana Peixoto, Jorge Pereira Lima · 2018 · Disease Models & Mechanisms
  50. Mitochondrial rewiring through mitophagy and mitochondrial biogenesis in cancer stem cells: A potential target for anti-CSC cancer therapy
    Prakash Priyadarshi Praharaj, Debasna Pritimanjari Panigrahi, Chandra Sekhar Bhol, Srimanta Patra, Soumya Ranjan Mishra, Kewal Kumar Mahapatra, Bishnu Prasad Behera, Amruta Singh, Shankargouda Patil, Sujit K. Bhutia · 2020 · Cancer Letters
  51. Crosstalk between the mitochondrial fission protein, Drp1, and the cell cycle is identified across various cancer types and can impact survival of epithelial ovarian cancer patients
    Deepak K. Tanwar, Danitra J. Parker, Priyanka Gupta, Brian Spurlock, Ronald David Alvarez, Malay Kumar Basu, Kasturi Mitra · 2016 · Oncotarget
  52. Mitochondrial dysfunction at the crossroad of cardiovascular diseases and cancer
    C. Rocca, T. Soda, E. D. De Francesco, Marco Fiorillo, Francesco Moccia, G. Viglietto, T. Angelone, N. Amodio · 2023 · Journal of Translational Medicine
  53. Mitochondrial Metabolism: Yin and Yang for Tumor Progression
    Lorea Valcárcel-Jiménez, Edoardo Gaude, Verónica Torrano, Christian Frezza, Arkaitz Carracedo · 2017 · Trends in Endocrinology and Metabolism
  54. Hypoxia- and MicroRNA-Induced Metabolic Reprogramming of Tumor-Initiating Cells
    Pit Ullmann, Martin Nurmik, Rubens Begaj, Serge Haan, Elisabeth Letellier · 2019 · Cells
  55. Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance
    Kazuhiro Ikeda, Kuniko Horie‐Inoue, Takashi Suzuki, Rutsuko Hobo, Norie Nakasato, Satoru Takeda, Satoshi Inoue · 2019 · Nature Communications
  56. Exploiting pancreatic cancer metabolism: challenges and opportunities
    Maria Chiara De Santis, Bruno Bockorny, Emilio Hirsch, Paola Cappello, Miriam Martini · 2024 · Trends in Molecular Medicine
  57. Drug discovery strategies in the field of tumor energy metabolism: Limitations by metabolic flexibility and metabolic resistance to chemotherapy
    Amoedo, N.D., Obre, E., Rossignol, R. · 2017 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  58. Plasticity of Cancer Stem Cell: Origin and Role in Disease Progression and Therapy Resistance
    Plabon Kumar Das, Suja Pillai, Md. Abdur Rakib, Jahan Ara Khanam, Vinod Gopalan, Alfred King-yin Lam, Farhadul Islam · 2020 · Stem Cell Reviews and Reports
  59. Metastasis in Pancreatic Ductal Adenocarcinoma: Current Standing and Methodologies
    Marina Ayres Pereira, Iok In Christine Chio · 2019 · Genes
  60. Tumorigenic Cell Reprogramming and Cancer Plasticity: Interplay between Signaling, Microenvironment, and Epigenetics
    V. Poli, L. Fagnocchi, A. Zippo · 2018 · Stem Cells International
  61. The Effect of Resveratrol and Quercetin on Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem Cell
    Mustafa Hoca, Eda Becer, Hilal Kabadayı, Sevinç Yücecan, Seda Vatansever · 2019 · Nutrition and Cancer
  62. Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models
    Ying Li, Meng Wang, Pei Zhi, Jian You, Jianqing Gao · 2017 · Oncotarget
  63. Signaling Pathways Regulating Redox Balance in Cancer Metabolism
    Maria Chiara De Santis, Paolo Ettore Porporato, Miriam Martini, Andrea Morandi · 2018 · Frontiers in Oncology
  64. Metabolic reprogramming and disease progression in cancer patients
    Laura Torresano, Cristina Nuevo‐Tapioles, Fulvio Santacatterina, Jose Manuel Cuezva · 2020 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  65. The m6A-Related mRNA Signature Predicts the Prognosis of Pancreatic Cancer Patients
    Zibo Meng, Qingchen Yuan, Jingyuan Zhao, Bo Wang, Shoukang Li, Rienk Offringa, Xin Jin, Heshui Wu · 2020 · Molecular Therapy — Oncolytics
  66. ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling
    Tao Zhu, Juyan Zheng, Wei Zhuo, Pinhua Pan, Min Li, Wei Zhang, Hong‐Hao Zhou, Yang Gao, Xi Li, Zhaoqian Liu · 2021 · Cell Death Discovery
  67. The contributions of cancer cell metabolism to metastasis
    Gloria Pascual, Diana Domínguez, Salvador Aznar Benitah · 2018 · Disease Models & Mechanisms
  68. PGC1α Suppresses Prostate Cancer Cell Invasion through ERRα Transcriptional Control
    Lorea Valcárcel-Jiménez, Alice Macchia, Eva Crosas‐Molist, Ariane Schaub-Clerigué, Laura Camacho, Natalia Martín-Martín, Paolo Cicogna, Cristina Viera-Bardón, Sonia Fernández‐Ruiz, Irene Rodríguez‐Hernández et al. · 2019 · Cancer Research
  69. Increased Oxidative Phosphorylation Is Required for Stemness Maintenance in Liver Cancer Stem Cells from Hepatocellular Carcinoma Cell Line HCCLM3 Cells
    Ge Liu, Qing Luo, Hong Li, Qiuping Liu, Yang Ju, Guanbin Song · 2020 · International Journal of Molecular Sciences
  70. Attacking the supply wagons to starve cancer cells to death
    Elizabeth M. Selwan, Brendan T. Finicle, Seong Min Kim, Aimee L. Edinger · 2016 · FEBS Letters
  71. Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts
    Benjamin Bian, Martin Bigonnet, Odile Gayet, Céline Loncle, Aurélie Maignan, Marine Gilabert, Vincent Moutardier, Stéphane Garcia, Olivıer Turrini, Jean‐Robert Delpéro et al. · 2017 · EMBO Molecular Medicine
  72. The Mechanism of Action of Biguanides: New Answers to a Complex Question
    Laura Di Magno, Fiorella Di Pastena, Rosa Bordone, Sonia Coni, Gianluca Canettieri · 2022 · Cancers
  73. Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies
    Jan Skoda, Karolina Borankova, Patric J. Jansson, Michael L.H. Huang, Renata Veselská, Des Raymond Richardson · 2018 · Pharmacological Research
  74. Posttranslational regulation of PGC‐1α and its implication in cancer metabolism
    Xiangjian Luo, Chaoliang Liao, Jing Quan, Can Cheng, Xu Zhao, Ann M. Bode, Ya Cao · 2019 · International Journal of Cancer
  75. The Sustained Induction of c-MYC Drives Nab-Paclitaxel Resistance in Primary Pancreatic Ductal Carcinoma Cells
    Erika Parasido, George S. Avetian, Aisha Naeem, Garrett T. Graham, Michael Jon Pishvaian, Eric F. Glasgow, Shaila Mudambi, Yi‐Chien Lee, Chukwuemeka U. Ihemelandu, Muhammad Umer Choudhry et al. · 2019 · Molecular Cancer Research
  76. Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells
    Petra Jagušt, Sonia Alcalá, Bruno Sáinz, Christopher Heeschen, Patricia Sancho · 2020 · World Journal of Stem Cells
  77. Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches
    Tiago M. A. Carvalho, Daria Di Molfetta, Maria Raffaella Greco, Tomas Koltai, Khalid Omer Alfarouk, Stephan J. Reshkin, Rosa Angela Cardone · 2021 · Cancers
  78. Mitochondria in cancer stem cells: Achilles heel or hard armor
    Xiaoxia Zheng, Junjie Chen, Yi-bo Sun, Tian-qing Chen, Jun Wang, Shi‐Cang Yu · 2023 · Trends in Cell Biology
  79. Mitochondrial Protein UQCRC1 is Oncogenic and a Potential Therapeutic Target for Pancreatic Cancer
    Qing Wang, Mengge Li, Yu Gan, Shu‐Heng Jiang, Jie Qiao, Wei Zhang, Yingchao Fan, Yuling Shen, Yanfang Song, Zihong Meng et al. · 2020 · Theranostics
  80. Metabolic heterogeneity in cancer: An overview and therapeutic implications
    Tong Yu, Wei‐Qiang Gao, Yanfeng Liu · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  81. Lactate promotes metastasis of normoxic colorectal cancer stem cells through PGC-1α-mediated oxidative phosphorylation
    Shuang Liu, Hui Zhao, Yibing Hu, Yan Zuo Chang, Yulong Mi, Xiaolan Li, Deding Tao, Jichao Qin · 2022 · Cell Death and Disease
  82. The Slow Cycling Phenotype: A Growing Problem for Treatment Resistance in Melanoma
    Antonio Ahn, Aniruddha Chatterjee, Michael Roger Eccles · 2017 · Molecular Cancer Therapeutics
  83. Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer
    Ekaterina Mameishvili, Ioannis Serafimidis, Sara Iwaszkiewicz, Mathias Lesche, Susanne Reinhardt, Nora Bölicke, Maren Büttner, Dimitris Stellas, Adriana Papadimitropoulou, Matthias J. Szabolcs et al. · 2019 · Proceedings of the National Academy of Sciences
  84. mRNA modification orchestrates cancer stem cell fate decisions
    Weicheng Liang, Ze‐Xiao Lin, Cong Du, Dongbo Qiu, Qi Zhang · 2020 · Molecular Cancer
  85. LINC00842 inactivates transcription co-regulator PGC-1α to promote pancreatic cancer malignancy through metabolic remodelling
    Xudong Huang, Ling Pan, Zhixiang Zuo, Mei Li, Lingxing Zeng, Rui Li, Ying Ye, Jialiang Zhang, Guandi Wu, Ruihong Bai et al. · 2021 · Nature Communications
  86. Control of cell metabolism by the epidermal growth factor receptor
    Laura A. Orofiamma, Dafne Vural, Costin N. Antonescu · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  87. Metabolic plasticity and cancer stem cell metabolism: Exploring the glycolysis-OXPHOS switch as a mechanism for resistance and tumorigenesis
    Keoh, Li Qing, Chiu, Ching-Feng, Ramasamy, Thamil Selvee · 2025 · Stem Cell Reviews and Reports
  88. Oncogenic Metabolism Acts as a Prerequisite Step for Induction of Cancer Metastasis and Cancer Stem Cell Phenotype
    Su Yeon Lee, Min Kyung Ju, Hyun Min Jeon, Yig Ji Lee, Cho Hee Kim, Hye Gyeong Park, Song Iy Han, Ho Sung Kang · 2018 · Oxidative Medicine and Cellular Longevity
  89. Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis
    Qiuli Liu, Wenqiang Yuan, Dali Tong, Gaolei Liu, Weihua Lan, Dianzheng Zhang, Hualiang Xiao, Yao Zhang, Zaoming Huang, Junjie Yang et al. · 2016 · Oncotarget
  90. COX6B2 drives metabolic reprogramming toward oxidative phosphorylation to promote metastasis in pancreatic ductal cancer cells
    Nie, Ke, Li, Jin, He, Xujun, Wang, Yuqing, Zhao, Qiongya, Du, Miaomiao, Sun, Hongwei, Wang, Jinjing, Lyu, Jianxin, Fang, Hezhi et al. · 2020 · Oncogenesis
  91. High metabolic rate and stem cell characteristics of esophageal cancer stem‐like cells depend on the Hsp27–AKT–HK2 pathway
    Chen‐Chi Liu, Kun‐Ta Chou, Jyuan‐Wei Hsu, Jiun-Han Lin, Tien‐Wei Hsu, David Hung‐Tsang Yen, Shih‐Chieh Hung, Han‐Shui Hsu · 2019 · International Journal of Cancer
  92. How does fascin promote cancer metastasis?
    Shengchen Lin, Matthew D. Taylor, Pankaj K. Singh, Shengyu Yang · 2020 · FEBS Journal
  93. Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer
    Danchen Wu, Asish Dasgupta, Austin D. Read, Rachel E. T. Bentley, Mehras Motamed, Kuang‐Hueih Chen, Ruaa Al‐Qazazi, Jeffrey D. Mewburn, Kimberly J. Dunham‐Snary, Elahe Alizadeh et al. · 2021 · Free Radical Biology and Medicine
  94. The roles of intratumour heterogeneity in the biology and treatment of pancreatic ductal adenocarcinoma
    Theodore Evan, Victoria M.-Y. Wang, Axel Behrens · 2022 · Oncogene
  95. Targeting stem cells in the realm of drug-resistant breast cancer
    Pranay Dey, Maitreyi Rathod, Abhijit De · 2019 · Breast Cancer Targets and Therapy
  96. Linking Metabolic Reprogramming, Plasticity and Tumor Progression
    Shuvalov, Oleg, Daks, Alexandra, Fedorova, Olga, Petukhov, Alexey, Barlev, Nickolai · 2021 · Cancers
  97. Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts
    Pawan Noel, Shaimaa Hussein, Serina Ng, Corina E. Antal, Wei Lin, Emily Rodela, Priscilla Delgado, Sanna Naveed, Michael Downes, Yin Chun Lin et al. · 2020 · Oncogenesis
  98. Targeting Redox Metabolism in Pancreatic Cancer
    Nadine Abdel Hadi, Gabriela Reyes‐Castellanos, Alice Carrier · 2021 · International Journal of Molecular Sciences
  99. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
    Gilles Rademaker, Vincent Hennequière, Laura Brohée, Marie‐Julie Nokin, Pierre Lovinfosse, Florence Durieux, Stéphanie Gofflot, Justine Bellier, Brunella Costanza, Michael F. Herfs et al. · 2018 · Oncogene
  100. Molecular profile of metastasis, cell plasticity and EMT in pancreatic cancer: a pre-clinical connection to aggressiveness and drug resistance
    Zhenli Guo, Milad Ashrafizadeh, Wei Zhang, Rongjun Zou, Gautam Sethi, Xianbin Zhang · 2023 · Cancer and Metastasis Reviews