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Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides

Weir, Graeme, Ramage, Lynne E., Akyol, Murat, Rhodes, Jonathan K., Kyle, Catriona J., Fletcher, Alison M., Craven, Thomas H., Wakelin, Sonia J., Drake, Amanda J., Gregoriades, Maria-Lena, Ashton, Ceri, Weir, Nick, van Beek, Edwin J.R., Karpe, Fredrik, Walker, Brian R., Stimson, Roland H.·2018·Cell Metabolism
DOI 10.1016/j.cmet.2018.04.020
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  1. Ahmed, 2010, An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81, Cell Metab., 11, 311, 10.1016/j.cmet.2010.02.012 · DOI
  2. Astrup, 1985, Contribution of BAT and skeletal muscle to thermogenesis induced by ephedrine in man, Am. J. Physiol., 248, E507
  3. Barbe, 2001, Measurements of white adipose tissue metabolism by microdialysis technique, Methods Mol. Biol., 155, 305
  4. Blondin, 2017, Inhibition of intracellular triglyceride lipolysis suppresses cold-induced brown adipose tissue metabolism and increases shivering in humans, Cell Metab., 25, 438, 10.1016/j.cmet.2016.12.005 · DOI · Paper page
  5. Blondin, 2015, Contributions of white and brown adipose tissues and skeletal muscles to acute cold-induced metabolic responses in healthy men, J. Physiol., 593, 701, 10.1113/jphysiol.2014.283598 · DOI
  6. Cannon, 1979, The physiological role of pyruvate carboxylation in hamster brown adipose tissue, Eur. J. Biochem., 94, 419, 10.1111/j.1432-1033.1979.tb12909.x · DOI
  7. Chakrabarty, 1983, Glycerokinase activity in human brown adipose tissue, J. Lipid Res., 24, 381, 10.1016/S0022-2275(20)37978-5 · DOI
  8. Chen, 2013, Brown fat activation mediates cold-induced thermogenesis in adult humans in response to a mild decrease in ambient temperature, J. Clin. Endocrinol. Metab., 98, E1218, 10.1210/jc.2012-4213 · DOI
  9. Chondronikola, 2016, Brown adipose tissue activation is linked to distinct systemic effects on lipid metabolism in humans, Cell Metab., 23, 1200, 10.1016/j.cmet.2016.04.029 · DOI
  10. Cypess, 2015, Activation of human brown adipose tissue by a beta3-adrenergic receptor agonist, Cell Metab., 21, 33, 10.1016/j.cmet.2014.12.009 · DOI · Paper page
  11. Din, 2016, Human brown adipose tissue [(15)O]O2 PET imaging in the presence and absence of cold stimulus, Eur. J. Nucl. Med. Mol. Imaging, 43, 1878, 10.1007/s00259-016-3364-y · DOI
  12. Goossens, 2008, Human adipose tissue blood flow and micromanipulation of human subcutaneous blood flow, Methods Mol. Biol., 456, 97, 10.1007/978-1-59745-245-8_7 · DOI
  13. Hao, 2015, Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism, Am. J. Physiol. Endocrinol. Metab., 308, E380, 10.1152/ajpendo.00277.2014 · DOI
  14. Hu, 2013, Characterization of human brown adipose tissue by chemical-shift water-fat MRI, AJR Am. J. Roentgenol., 200, 177, 10.2214/AJR.12.8996 · DOI
  15. Janderova, 2003, Human mesenchymal stem cells as an in vitro model for human adipogenesis, Obes. Res., 11, 65, 10.1038/oby.2003.11 · DOI · Paper page
  16. Jensen, 2007, In vivo and in vitro microdialysis sampling of free fatty acids, J. Pharm. Biomed. Anal., 43, 1751, 10.1016/j.jpba.2006.12.014 · DOI
  17. Kiskinis, 2014, RIP140 represses the “brown-in-white” adipocyte program including a futile cycle of triacylglycerol breakdown and synthesis, Mol. Endocrinol., 28, 344, 10.1210/me.2013-1254 · DOI
  18. Labbe, 2015, In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis, FASEB J., 29, 2046, 10.1096/fj.14-266247 · DOI
  19. Lee, 2011, Hot fat in a cool man: infrared thermography and brown adipose tissue, Diabetes Obes. Metab., 13, 92, 10.1111/j.1463-1326.2010.01318.x · DOI
  20. Lee, 2014, Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans, Diabetes, 63, 3686, 10.2337/db14-0513 · DOI
  21. Ma, 1986, Uptake of glucose and release of fatty acids and glycerol by rat brown adipose tissue in vivo, Can. J. Physiol. Pharmacol., 64, 609, 10.1139/y86-101 · DOI
  22. Macfarlane, 2014, Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver, Am. J. Physiol. Gastrointest. Liver Physiol., 307, G760, 10.1152/ajpgi.00030.2014 · DOI
  23. Muller, 1996, Measurement of interstitial muscle glucose and lactate concentrations during an oral glucose tolerance test, Am. J. Physiol., 271, E1003
  24. Muzik, 2013, 15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat, J. Nucl. Med., 54, 523, 10.2967/jnumed.112.111336 · DOI
  25. Nagao, 2017, Increased dynamics of tricarboxylic acid cycle and glutamate synthesis in obese adipose tissue: in vivo metabolic turnover analysis, J. Biol. Chem., 292, 4469, 10.1074/jbc.M116.770172 · DOI
  26. Orava, 2011, Different metabolic responses of human brown adipose tissue to activation by cold and insulin, Cell Metab., 14, 272, 10.1016/j.cmet.2011.06.012 · DOI · Paper page
  27. Ouellet, 2012, Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans, J. Clin. Invest., 122, 545, 10.1172/JCI60433 · DOI · Paper page
  28. Raiko, 2015, Brown adipose tissue triglyceride content is associated with decreased insulin sensitivity, independently of age and obesity, Diabetes Obes. Metab., 17, 516, 10.1111/dom.12433 · DOI
  29. Ramage, 2016, Glucocorticoids acutely increase brown adipose tissue activity in humans, revealing species-specific differences in UCP-1 regulation, Cell Metab., 24, 130, 10.1016/j.cmet.2016.06.011 · DOI
  30. Rosdahl, 1998, Metabolite levels in human skeletal muscle and adipose tissue studied with microdialysis at low perfusion flow, Am. J. Physiol., 274, E936
  31. Stahle, 1991, A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis, J. Pharmacol. Methods, 25, 41, 10.1016/0160-5402(91)90021-V · DOI
  32. Yoneshiro, 2011, Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men, Obesity (Silver Spring), 19, 13, 10.1038/oby.2010.105 · DOI

Metadata

Authors
Weir, G., Ramage, L. E., Akyol, M., Rhodes, J. K., Kyle, C. J., Fletcher, A. M., Craven, T. H., Wakelin, S. J., Drake, A. J., Gregoriades, M.-L., Ashton, C., Weir, N., van Beek, E. J. R., Karpe, F., Walker, B. R., & Stimson, R. H.
Venue
Cell Metabolism
Publisher
Elsevier BV
Published
2018-06
Volume
27
Issue
6
Pages
1348-1355.e4
ISSN
1550-4131
DOI
10.1016/j.cmet.2018.04.020
Cited by
133
References
4
Language
en
Licence
Funders
  • National Rosacea Society
  • Wellcome Trust (107049/Z/15/Z)
  • Medical Research Council (MR/K010271/1)

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CoChat. (2026). Citation check: Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides. https://app.cochat.ai/papers/10.1016/j.cmet.2018.04.020
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Weir, G., Ramage, L. E., Akyol, M., Rhodes, J. K., Kyle, C. J., Fletcher, A. M., Craven, T. H., Wakelin, S. J., Drake, A. J., Gregoriades, M.-L., Ashton, C., Weir, N., van Beek, E. J. R., Karpe, F., Walker, B. R., & Stimson, R. H. (2018). Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides. Cell Metabolism. https://doi.org/10.1016/j.cmet.2018.04.020

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.