The DOI matches its Crossref record; 154 of the 154 references it cites were found in a registry or an index.
Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases
Open accessAbstract
High levels of cholesterol are generally considered to be associated with atherosclerosis. In the past two decades, however, a number of studies have shown that excess cholesterol accumulation in various tissues and organs plays a critical role in the pathogenesis of multiple diseases. Here, we summarize the effects of excess cholesterol on disease pathogenesis, including liver diseases, diabetes, chronic kidney disease, Alzheimer's disease, osteoporosis, osteoarthritis, pituitary-thyroid axis dysfunction, immune disorders, and COVID-19, while proposing that excess cholesterol-induced toxicity is ubiquitous. We believe this concept will help broaden the appreciation of the toxic effect of excess cholesterol, and thus potentially expand the therapeutic use of cholesterol-lowering medications.
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Cites
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Zadoorian, A., Du, X., & Yang, H. (2023) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00845-0 · Cited by 617
The role of remnant cholesterol beyond low-density lipoprotein cholesterol in diabetes mellitus
Hu, X., Liu, Q., Guo, X., Wang, W., Yu, B., Liang, B., Zhou, Y., Dong, H., & Lin, J. (2022) · Cardiovascular Diabetology · doi:10.1186/s12933-022-01554-0 · Cited by 150
Inhibition of microRNA-33b in humanized mice ameliorates nonalcoholic steatohepatitis
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An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis
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Metadata
- Authors
- Song, Y., Liu, J., Zhao, K., Gao, L., & Zhao, J.
- Venue
- Cell Metabolism
- Publisher
- Elsevier BV
- Published
- 2021-10
- Volume
- 33
- Issue
- 10
- Pages
- 1911-1925
- ISSN
- 1550-4131 (ISSN-L)
- OpenAlex
- W3203260025
- Cited by
- 322
- References
- 154
- FWCI
- 36.01
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Song, Y., Liu, J., Zhao, K., Gao, L., & Zhao, J. (2021). Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases. Cell Metabolism. https://doi.org/10.1016/j.cmet.2021.09.001
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
