Cited by 31Wound Healing and TreatmentsDiabetic Foot Ulcer Assessment and ManagementPressure Ulcer Prevention and Management

Microbiology of chronic leg and pressure ulcers: clinical significance and implications for treatment

Ebright, John R.·2005·Nursing Clinics of North America

Abstract

Chronic pressure ulcers and leg ulcers are common, especially in the elderly, and are a source of much distress and disability. Health care providers must distinguish between clinically unimportant but predictable colonization of these wounds and clinically relevant infection.Infection may present as increased local pain, cellulitis, local abscess,necrotizing fasciitis, osteomyelitis, bacteremia, or sepsis. For most of these conditions, systemic antibiotics are necessary. The use of topical antimicrobial agents as a means of promoting healing in clinically uninfected wounds is a subject of active investigation at this time. Currently, evidence is insufficient to support routine use of anti-microbial agents for this purpose. A quantitative tissue culture taken from the ulcer bed, revealing greater than 10(5) organisms/g of tissue appears to increase the risk of failure of ulcer wound closure by graft or flap. A short course of topical or systemic antibiotics before surgery in these instances is advisable.

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Crossref · 10.1016/j.cnur.2004.09.003

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53 of 53 references verified0 citation errors · 0 not checkable

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Authors
Ebright, J. R.
Affiliations
Wayne State University (US)
Corresponding author
Ebright, John R.
Venue
Nursing Clinics of North America
Publisher
Elsevier BV
Published
2005-06
Volume
40
Issue
2
Pages
207-216
ISSN
0029-6465 (ISSN-L)
OpenAlex
W2084433793
Cited by
31
References
53
Citations by year
2024: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 1 · 2017: 1 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 4 · 2012: 2
FWCI
0.13
Type
journal article
Language
en
Open access
closed
Locations
  • Nursing Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
  • Health Sciences › Health Professions › Occupational Therapy › Pressure Ulcer Prevention and Management
Keywords
chronic pressure ulcers, leg ulcers, wound infection, wound colonization, necrotizing fasciitis, osteomyelitis, sepsis, topical antimicrobial agents, wound healing, surgical wound closure, elderly patients
MeSH terms
Chronic Disease, Pressure Ulcer, Humans, Leg Ulcer, Wound Healing, Wound Infection

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