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Cited by 46Electrochemical sensors and biosensorsPolymer Surface Interaction StudiesConducting polymers and applications

Reviewing the use of chitosan and polydopamine for electrochemical sensing

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Prabhu, Akash, Crapnell, Robert D., Eersels, Kasper, van Grinsven, Bart, Kunhiraman, Aruna K., Singla, Pankaj, McClements, Jake, Banks, Craig E. +2 more·2022·Current Opinion in Electrochemistry
DOI 10.1016/j.coelec.2021.100885
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  • Despite high analytical sensitivity under controlled buffer conditions, translation of PDA-based sensing platforms to real salivary samples remains challenging.

    “Despite the high analytical sensitivity achieved by PDA-based sensing platforms under controlled buffer conditions,41,95 the translation of these systems to real salivary samples remains challenging.”

    From Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges (2026) · cites this paper as [95]

    The PDA-based sensors section (page unavailable) reports detection at approximately 3 fg/mL for one PDA-based biosensor and a fivefold signal increase for another tested in buffer. The Future work and outlook section discusses limitations of PDA sensors, but our copy does not address testing in real salivary samples or establish that translation to saliva is challenging. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

  • Buffer systems, artificial saliva, and selected saliva/serum samples show that PDA-based biosensing platforms can achieve improved biomolecule immobilization, signal transduction, fluorescence/electrochemical/SERS detection, and salivary biomarker analysis.

    “Buffer systems, artificial saliva, and selected saliva/serum samples show improved biomolecule immobilization, signal transduction, fluorescence/electrochemical/SERS detection, and salivary biomarker analysis.”

    From Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges (2026) · cites this paper as [95]

    The PDA-based sensors section (page unavailable) describes PDA-assisted adhesion and immobilization, electrochemical biomolecule detection, and a guanine response measured in buffer. It does not support the claim about artificial saliva, saliva or serum samples, fluorescence or SERS detection, or salivary biomarker analysis. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 27

  1. Nagel B, Dellweg H, Gierasch LM, Dellweg H, Engels JW, Fox JL, Gierasch LM, Gregson RP, Heinritz B, Leuenberger HGW, Moo- Young M, Moser A, Nagel B, Nyeste L, Pcnasse L, Petersen GB, Van Montagu M, Yamada Y: Glossary for chemists of terms used in biotechnology. Pure Appl Chem 1992, 64:143-168, https://doi.org/10.1351/pac199264010143. · DOI
  2. George A, Sanjay MR, Srisuk R, Parameswaranpillai J, Siengchin S: A comprehensive review on chemical properties and applications of biopolymers and their composites. Int J Biol Macromol 2020, 154:329-338, https://doi.org/10.1016/ j.ijbiomac.2020.03.120. · DOI
  3. Vinod A, Sanjay MR, Suchart S, Jyotishkumar P: Renewable and sustainable biobased materials: an assessment on biofibers, biofilms, biopolymers and biocomposites. J Clean Prod 2020, 258, 120978, https://doi.org/10.1016/j.jclepro.2020.120978. · DOI
  4. Alishahi AA: Chitosan: a bioactive polysaccharide in marine- based foods. In The complex world of polysaccharides. Edited by Karunaratne DN, Rijeka: Intech; 2012:409-428, https://doi.org/ 10.5772/48199. · DOI
  5. Tharanathan RN, Kittur FS: Chitin -the undisputed biomole- cule of great potential. Crit Rev Food Sci Nutr 2003, 43:61-87, https://doi.org/10.1080/10408690390826455. · DOI
  6. Vukajlovic D, Parker J, Bretcanu O, Novakovic K: Chitosan based polymer/bioglass composites for tissue engineering applications. Mater Sci Eng C 2019, 96:955-967, https://doi.org/ 10.1016/j.msec.2018.12.026. · DOI
  7. Ryan C, Alcock E, Buttimer F, Schmidt M, Clarke D, Pemble M, Bardosova M: Synthesis and characterisation of cross-linked chitosan composites functionalised with silver and gold nanoparticles for antimicrobial applications. Sci Technol Adv Mater 2017, 18:528-540, https://doi.org/10.1080/ 14686996.2017.1344929. · DOI
  8. Batul R, Tamanna T, Khaliq A, Yu A: Recent progress in the biomedical applications of polydopamine nanostructures. Biomater. Sci. 2017, 5:1204-1229, https://doi.org/10.1039/ c7bm00187h. · DOI
  9. Ding YH, Floren M, Tan W: Mussel-inspired polydopamine for bio-surface functionalization. Biosurface and Biotribology 2016, 2:121-136, https://doi.org/10.1016/j.bsbt.2016.11.001. · DOI
  10. Liu Y, Ai K, Lu L: Polydopamine and its derivative materials: synthesis and promising applications in energy, environ- mental, and biomedical fields. Chem Rev 2014, 114: 5057-5115, https://doi.org/10.1021/cr400407a. · DOI · Paper page
  11. Liu J, Wang X, Wang T, Li D, Xi F, Wang J, Wang E: Func- tionalization of monolithic and porous three-dimensional graphene by one-step chitosan electrodeposition for enzy- matic biosensor. ACS Appl Mater Interfaces 2014, 6: 19997-20002, https://doi.org/10.1021/am505547f. · DOI
  12. Pavinatto A, de Almeida Mattos AV, Malpass ACG, Okura MH, Balogh DT, Sanfelice RC: Coating with chitosan-based edible films for mechanical/biological protection of strawberries. Int J Biol Macromol 2020, 151:1004-1011, https://doi.org/10.1016/ j.ijbiomac.2019.11.076. · DOI
  13. Poletti F, Favaretto L, Kovtun A, Treossi E, Corticelli F, Gazzano M, Palermo V, Zanardi C, Melucci M: Electrochemical sensing of glucose by chitosan modified graphene oxide. JPhys Mater 2020, 3, 014011, https://doi.org/10.1088/2515-7639/ ab5e51. · DOI
  14. Shukla SK, Mishra AK, Arotiba OA, Mamba BB: Chitosan-based nanomaterials: a state-of-the-art review. Int J Biol Macromol 2013, 59:46-58, https://doi.org/10.1016/j.ijbiomac.2013.04.043. · DOI
  15. Lamaoui A, Palacios-Santander JM, Amine A, Cubillana- Aguilera L: Molecularly imprinted polymers based on poly- dopamine: assessment of non-specific adsorption. Micro- chem J 2021, 164:106043, https://doi.org/10.1016/ j.microc.2021.106043. · DOI
  16. Miao J, Liu A, Wu L, Yu M, Wei W, Liu S: Magnetic ferroferric oxide and polydopamine molecularly imprinted polymer nanocomposites based electrochemical impedance sensor for the selective separation and sensitive deter- mination of dichlorodiphenyltrichloroethane (DDT). Anal Chim Acta 2020, 1095:82 -92, https://doi.org/10.1016/j.aca. 2019.10.027. · DOI
  17. Leibl N, Duma L, Gonzato C, Haupt K: Polydopamine-based molecularly imprinted thin films for electro-chemical sensing of nitro-explosives in aqueous solutions. Bioelectrochemistry 2020, 135:107541, https://doi.org/10.1016/ j.bioelechem.2020.107541. · DOI
  18. Crapnell RD, Hudson A, Foster CW, Eersels K, van Grinsven B, Cleij TJ, Banks CE, Peeters M: Recent advances in electro- synthesized molecularly imprinted polymer sensing plat- forms for bioanalyte detection. Sensors 2019, 19:1204, https:// doi.org/10.3390/s19051204. · DOI
  19. Liu K, Wei WZ, Zeng JX, Liu XY, Gao YP: Application of a novel electrosynthesized polydopamine-imprinted film to the capacitive sensing of nicotine. Anal Bioanal Chem 2006, 385: 724-729, https://doi.org/10.1007/s00216-006-0489-z. · DOI
  20. Tretjakov A, Syritski V, Reut J, Boroznjak R, Volobujeva O, Öpik A: Surface molecularly imprinted polydopamine films for recognition of immunoglobulin G. Microchim Acta 2013, 180: 1433-1442, https://doi.org/10.1007/s00604-013-1039-y. · DOI
  21. Kanyong P, Rawlinson S, Davis J: Fabrication and electro- chemical characterization of polydopamine redox polymer modified screen-printed carbon electrode for the detection of guanine. Sensor Actuator B Chem 2016, 233:528-534, https:// doi.org/10.1016/j.snb.2016.04.099. · DOI
  22. Zhang W, Tang Y, Liu J, Ma Y, Jiang L, Huang W, Huo FW, Tian D: An electrochemical sensor for detecting triglyceride based on biomimetic polydopamine and gold nano- composite. J Mater Chem B 2014, 2:8490-8495, https://doi.org/ 10.1039/c4tb01439a. · DOI
  23. Salgado R, del Valle MA, Duran BG, Pardo MA, Armijo F: Opti- mization of dopamine determination based on nanowires PEDOT/polydopamine hybrid film modified electrode. J Appl Electrochem 2014, 44:1289-1294, https://doi.org/10.1007/ s10800-014-0728-5. · DOI
  24. Kim S, Jang LK, Jang M, Lee S, Hardy JG, Lee JY: Electrically conductive polydopamine-polypyrrole as high performance biomaterials for cell stimulation in vitro and electrical signal recording in vivo. ACS Appl Mater Interfaces 2018, 10: 33032-33042, https://doi.org/10.1021/acsami.8b11546. · DOI
  25. a Khumsap T, Bamrungsap S, Thu VT, Nguyen LT: Epitope- imprinted polydopamine electrochemical sensor for oval- bumin detection. Bioelectrochemistry 2021, 140:107805, https:// doi.org/10.1016/j.bioelechem.2021.107805. · DOI
  26. Feng T, Ji W, Zhang Y, Wu F, Tang Q, Wei H, Mao L, Zhang M: Zwitterionic polydopamine engineered interface for in vivo sensing with high biocompatibility. Angew Chem Int Ed 2020, 59: 23445-23449, https://doi.org/10.1002/anie.202010675. · DOI
  27. Aguilar-Ferrer D, Szewczyk J, Coy E: Recent developments in polydopamine-based photocatalytic nanocomposites for energy production: physico-chemical properties and per- spectives. Catal Today 2021, https://doi.org/10.1016/ j.cattod.2021.08.016. · DOI

Cited by

Sorted by citations

Authors
Prabhu, A., Crapnell, R. D., Eersels, K., van Grinsven, B., Kunhiraman, A. K., Singla, P., McClements, J., Banks, C. E., Novakovic, K., & Peeters, M.
Affiliations
  • Manchester Metropolitan University (GB)
  • Maastricht University (NL)
  • Rathinam Technical Campus (IN)
  • Newcastle University (GB)
Corresponding author
Peeters, Marloes
ORCID
Venue
Current Opinion in Electrochemistry
Publisher
Elsevier BV
Published
2022-04
Volume
32
Pages
100885
ISSN
2451-9103 (ISSN-L)
DOI
10.1016/j.coelec.2021.100885
OpenAlex
W3214516409
Cited by
46
References
0
Citations by year
2026: 11 · 2025: 12 · 2024: 8 · 2023: 9 · 2022: 6
FWCI
0.36
Type
journal article
Language
en
Open access
Licence
Locations
  • Current Opinion in Electrochemistry (publishedVersion)
  • e-space (Manchester Metropolitan University) (acceptedVersion)
  • Research Publications (Maastricht University) (submittedVersion, other-oa)
  • Research Explorer (The University of Manchester) (submittedVersion)
  • Newcastle University ePrints (Newcastle Univesity) (cc-by-nc-nd)
Funders
  • European Commission (TEMPER 893371)
  • Rosetrees Trust (Seedcorn2020∖100303)
Topics
  • Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
  • Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
  • Physical Sciences › Materials Science › Polymers and Plastics › Conducting polymers and applications
Keywords
chitosan, polydopamine, electrochemical biosensing, biopolymers, self-assembled monolayers, surface modification, mucoadhesion, antibacterial properties, polysaccharides, self-adhesion

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