Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
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ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTPolydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical FieldsYanlan Liu†‡, Kelong Ai†, and Lehui Lu*†View Author Information† State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People's Republic of China‡ Chinese Academy of Sciences, Beijing 100039, People's Republic of China*Tel.: +86 431 85262418. Fax: +86 431 85262406. E-mail: [email protected]Cite this: Chem. Rev. 2014, 114, 9, 5057–5115Publication Date (Web):February 11, 2014Publication History Received27 July 2013Published online11 February 2014Published inissue 14 May 2014https://pubs.acs.org/doi/10.1021/cr400407ahttps://doi.org/10.1021/cr400407areview-articleACS PublicationsCopyright © 2014 American Chemical SocietyRequest reuse permissionsArticle Views110289Altmetric-Citations3853LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking…
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PDA-based strategies have shown encouraging potential in oral hard tissue repair and implant modification.
“Although PDA-based strategies have shown encouraging potential in oral hard tissue repair and implant modification, the current evidence should be interpreted according to different levels of experimental validation.36”
From Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges (2026) · cites this paper as [36]
Coating adhesion durability, wear resistance, interfacial degradation, batch-to-batch reproducibility, and the biological safety of degradation products remain critical issues before PDA-modified implants or scaffolds can be considered clinically mature.
“In particular, coating adhesion durability, wear resistance, interfacial degradation, batch-to-batch reproducibility, and the biological safety of degradation products remain critical issues before PDA-modified implants or scaffolds can be considered clinically mature.36,40,41”
From Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges (2026) · cites this paper as [36]
Current evidence for PDA-based drug delivery, antibacterial/anti-inflammatory systems, and tumor therapies remains largely preclinical.
“Although PDA-based drug delivery, antibacterial/anti-inflammatory systems, and tumor therapies show considerable promise, their current evidence remains largely preclinical.36”
From Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges (2026) · cites this paper as [36]
In vitro mineralization, bonding tests, cell culture, and short-term animal studies suggest that PDA can promote hydroxyapatite nucleation, dentin sealing, cell adhesion, osteogenic differentiation, osseointegration, and surface biofunctionalization.
“In vitro mineralization, bonding tests, cell culture, and short-term animal studies suggest that PDA can promote hydroxyapatite nucleation, dentin sealing, cell adhesion, osteogenic differentiation, osseointegration, and surface biofunctionalization.”
From Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges (2026) · cites this paper as [36]
PDA-assisted surface modification is expanding its applications to not only bone biosubstitutes but also cardiovascular devices, biosensors, neuron pseudosubstitutes, and sustainable drug delivery.
“the PDA-assisted surface modification is expanding its applications to not only bone biosubstitutes but also cardiovascular devices, biosensors, neuron pseudosubstitutes, and sustainable drug delivery [18, 99–101].”
From Polydopamine-Assisted Surface Modification for Bone Biosubstitutes (2016) · cites this paper as [99]
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“The PDA formation m chanism consis s of several complex s eps that remain a subject of debate (Figure 2) [4,5].”
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Self-citation
- Authors
- Liu, Y., Ai, K., & Lu, L.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Lu, Lehui
- Venue
- Chemical Reviews
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-02-11
- Volume
- 114
- Issue
- 9
- Pages
- 5057-5115
- ISSN
- 0009-2665 (ISSN-L)
- 1520-6890
- OpenAlex
- W2322562148
- Cited by
- 4,794
- References
- 7
- Citations by year
- 2026: 253 · 2025: 344 · 2024: 410 · 2023: 403 · 2022: 489 · 2021: 496 · 2020: 508 · 2019: 550 · 2018: 446 · 2017: 341 · 2016: 292 · 2015: 190 · 2014: 71
- FWCI
- 10.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Physical Sciences › Materials Science › Polymers and Plastics › Conducting polymers and applications
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Keywords
- polydopamine, dopamine oxidation, polymer synthesis, energy applications, environmental applications, biomedical applications, surface coating, electrochemical energy storage, water treatment, biomedical materials, biomaterials, nanomaterials, ion adsorption, biomimetic materials, self-assembly, electrocatalysis, supercapacitors, lithium-ion batteries
- MeSH terms
- Animals, Humans, Indoles, Polymers, Electric Power Supplies, Biosensing Techniques, Water Purification
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