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Cited by 289

The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.

Pattern recognition: recent insights from Dectin-1

Open access
Reid, Delyth M, Gow, Neil AR, Brown, Gordon D·2009·Current Opinion in Immunology

Abstract

The beta-glucan receptor Dectin-1 is an archetypical non-toll-like pattern recognition receptor expressed predominantly by myeloid cells, which can induce its own intracellular signalling and can mediate a variety of cellular responses, such as cytokine production. Recent identification of the components of these signalling pathways, such as Syk kinase, CARD9 and Raf-1, has provided novel insights into the molecular mechanisms underlying Dectin-1 function. Furthermore, a broader appreciation of the cellular responses mediated by this receptor and the effects of interactions with other receptors, including the TLRs, have greatly furthered our understanding of innate immunity and how this drives the development of adaptive immunity, particularly Th17 responses. Recent studies have highlighted the importance of Dectin-1 in anti-fungal immunity, in both mice and humans, and have suggested a possible involvement of this receptor in the control of mycobacterial infections.

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Metadata

Authors
Reid, D. M., Gow, N. A., & Brown, G. D.
Venue
Current Opinion in Immunology
Publisher
Elsevier BV
Published
2009-02
Volume
21
Issue
1
Pages
30-37
ISSN
0952-7915 (ISSN-L)
OpenAlex
W2008415419
Cited by
289
References
47
FWCI
1.71
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Pattern recognition: recent insights from Dectin-1. https://app.cochat.ai/papers/10.1016/j.coi.2009.01.003
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Reid, D. M., Gow, N. A., & Brown, G. D. (2009). Pattern recognition: recent insights from Dectin-1. Current Opinion in Immunology. https://doi.org/10.1016/j.coi.2009.01.003

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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