Regulation of NF-κB by ubiquitination

Cited by (260)

Items 101–200 of 260

1. Deubiquitylating enzymes: potential target in autoimmune diseases
   Niraj Parihar, Lokesh Kumar Bhatt · 2021 · Inflammopharmacology
2. Amorfrutin A inhibits TNF-α-induced NF-κB activation and NF-κB-regulated target gene products
   Hui Rong Shi, Juan Ma, Chunliu Mi, Jing Li, Fei Wang, Jung Joon Lee, Xuejun Jin · 2014 · International Immunopharmacology
3. A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes
   Ahmed Murtaza Mehdi, Emma E. Hamilton‐Williams, Alexandre S. Cristino, Anette G. Ziegler, Ezio E. Bonifacio, Kim‐Anh Lê Cao, Mark Anglin Harris, Ranjeny Thomas · 2018 · JCI Insight
4. Schisantherin A attenuates sepsis-induced acute kidney injury by suppressing inflammation via regulating the NRF2 pathway
   Yuan Gui, Youjing Yang, Deyu Xu, Shasha Tao, Jianzhong Li · 2020 · Life Sciences
5. Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
   Ananth Kumar Kammala, Angela Mosebarger, Enkhtuya Radnaa, Emma Rowlinson, Natasha Vora, Stephen J. Fortunato, Surendra Sharma, Melody Safarzadeh, Ramkumar Menon · 2023 · Frontiers in Immunology
6. USP7 Inhibits Osteoclastogenesis via Dual Effects of Attenuating TRAF6/TAK1 Axis and Stimulating STING Signaling
   Ziang Xie, Yizheng Wu, Yang Shen, Jiandong Guo, Putao Yuan, Qingliang Ma, Shiyu Wang, Zhiwei Jie, Hongyi Zhou, Shunwu Fan et al. · 2023 · Aging and Disease
7. The application of ubiquitin ligases in the PROTAC drug design
   Yilin Chen, Jianping Jin · 2020 · Acta Biochimica et Biophysica Sinica
8. Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence
   Parmjit Jat, Neil D. Perkins, Sophia N. Mowla · 2013 · OncoTargets and Therapy
9. USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection
   Phatcharida Jantaree, Supattra Chaithongyot, Olga V. Sokolova, Michael Naumann · 2022 · Cellular and Molecular Life Sciences
10. Protein ubiquitination in lymphoid malignancies
    Yibin Yang, Louis M. Staudt · 2014 · Immunological Reviews
11. SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function
    Aurélien Schwob, Élodie Teruel, Louise Dubuisson, Florence Lormières, Pauline Verlhac, Yakubu Princely Abudu, Janelle Gauthier, Marie Naoumenko, Fanny-Meï Cloarec-Ung, Mathias Faure et al. · 2019 · Scientific Reports
12. The characteristics of FBXO7 and its role in human diseases
    Yeling Zhong, Jinyun Li, Meng Ye, Xiaofeng Jin · 2022 · Gene
13. SAGA DUB-Ubp8 Deubiquitylates Centromeric Histone Variant Cse4
    Claudia Canzonetta, Stefano Vernarecci, Michele Iuliani, Cristina Marracino, Claudia Belloni, Paola Ballario, Patrizia Filetici · 2015 · G3 Genes Genomes Genetics
14. SUMO/deSUMOylation of the BRI1 brassinosteroid receptor modulates plant growth responses to temperature
    Maria Augusta Naranjo-Arcos, Moumita Srivastava, Florian Deligne, Prakash Kumar Bhagat, Mansi Mansi, Ari Sadanandom, Grégory Vert · 2023 · Proceedings of the National Academy of Sciences
15. CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation
    Richard Hunte, Patricia Alonso, Remy Thomas, Cassandra A Bazile, Juan Carlos Ramos, Louise van der Weyden, Juan Domínguez‐Bendala, Wasif Noor Khan, Noula Shembade · 2018 · PLoS Pathogens
16. Anti-Inflammatory Effects of Shenfu Injection against Acute Lung Injury through Inhibiting HMGB1-NF-κB Pathway in a Rat Model of Endotoxin Shock
    Xia Liu, Fei Ai, Hui Li, Qin Xu, Liyan Mei, Jifei Miao, Quan Wen, Chaoying Zhang, Saixia Zhang, Jianhong Zhou et al. · 2019 · Evidence-based Complementary and Alternative Medicine
17. Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis
    Aisha Siddiqah Ahmed, Mahmood Ahmed, Jian Li, Harvest F. Gu, Georgy Ya. Bakalkin, André Stark, Helena Erlandsson Harris · 2014 · International Journal of Rheumatic Diseases
18. Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway
    Yael Litvak, Shir Sharon, Meirav Hyams, Li Zhang, Simi Koby, Naama Katsowich, Shira Dishon, Gabriel Nussbaum, Na Dong, Feng Shao et al. · 2017 · PLoS Pathogens
19. RNF31 Regulates Skin Homeostasis by Protecting Epidermal Keratinocytes from Cell Death
    Yong Tang, Hailin Tu, Guangna Liu, Guoxing Zheng, Mingchao Wang, Lin Li, Xueqiang Zhao, Xin Lin · 2018 · The Journal of Immunology
20. Molecular targeting of renal inflammation using drug delivery technology to inhibit NF-κB improves renal recovery in chronic kidney disease
    Alejandro Chade, Maxx L. Williams, Jason Edward Engel, Erika Williams, Gene Lee Bidwell · 2020 · American Journal of Physiology-Renal Physiology
21. Remodeling without destruction: non-proteolytic ubiquitin chains in neural function and brain disorders
    Alexis S. Zajicek, Wei‐Dong Yao · 2020 · Molecular Psychiatry
22. Gastroprotective effect of eupatilin, a polymethoxyflavone from Artemisia argyi H.Lév. & Vaniot, in ethanol-induced gastric mucosal injury via NF-κB signaling pathway
    Kaicheng Du, Changwei Zheng, Zhulingzhi Kuang, Yiwei Sun, Yumeng Wang, Shuang Li, Dali Meng · 2023 · Journal of Ethnopharmacology
23. Inhibition of p-IκBα Ubiquitylation by Autophagy-Related Gene 7 to Regulate Inflammatory Responses to Bacterial Infection
    Yan Ye, Shirui Tan, Xikun Zhou, Xuefeng Li, Michael C. Jundt, Natalie Lichter, Alec Hidebrand, Archana Dhasarathy, Min Wu · 2015 · The Journal of Infectious Diseases
24. Dietary supplementation of chitosan affects milk performance, markers of inflammatory response and antioxidant status in dairy cows
    Ya-Guang Zheng, B.Q. Zhang, Jingwei Qi, Yanli Zhao, Xiaoyu Guo, Binlin Shi, Sumei Yan · 2021 · Animal Feed Science and Technology
25. Covalent Modification of the NF-κB Essential Modulator (NEMO) by a Chemical Compound Can Regulate Its Ubiquitin Binding Properties in Vitro
    Christopher Hooper, Shawn S. Jackson, Emma E. Coughlin, Joshua J. Coon, Shigeki Miyamoto · 2014 · Journal of Biological Chemistry
26. 15-Deoxy-Δ12,14-Prostaglandin J2 Modifies Components of the Proteasome and Inhibits Inflammatory Responses in Human Endothelial Cells
    Simone Marcone, Paul Evans, Desmond J. Fitzgerald · 2016 · Frontiers in Immunology
27. DNA Binding and Phosphorylation Regulate the Core Structure of the NF-κB p50 Transcription Factor
    Matthias Vonderach, Dominic P. Byrne, Perdita E. Barran, Patrick A. Eyers, Claire E. Eyers · 2018 · Journal of the American Society for Mass Spectrometry
28. The E2 ubiquitin-conjugating enzyme UbcH5c: an emerging target in cancer and immune disorders
    Yuan Zhou, Runzhe Chen, Xiaofang Luo, Weidong Zhang, Jiang‐Jiang Qin · 2020 · Drug Discovery Today
29. Interplay between ubiquitylation and SUMOylation: Empowered by phase separation
    Jianping Jin · 2019 · Journal of Biological Chemistry
30. USP3 plays a critical role in the induction of innate immune tolerance
    Tianhao Duan, Yanchun Feng, Yang Du, Changsheng Xing, Junjun Chu, Jiayu Ou, Xin Liu, Motao Zhu, Qian Chen, Bingnan Yin et al. · 2023 · EMBO Reports
31. Netrin-1 protects the SH-SY5Y cells against amyloid beta neurotoxicity through NF-κB/Nrf2 dependent mechanism
    Elham Zamani, Mohsen Parviz, Mehrdad Roghani, Marjan Hosseini, Parvaneh Mohseni Moghaddam, Marjan Nikbakhtzadeh · 2020 · Molecular Biology Reports
32. Alternative splicing coupled with transcript degradation modulates OAS1g antiviral activity
    Luke S. Frankiw, Mati Mann, Guideng Li, Alok V. Joglekar, David Baltimore · 2019 · RNA
33. Vitamin C exerts beneficial hepatoprotection against Concanavalin A-induced immunological hepatic injury in mice through inhibition of NF-κB signal pathway
    Tao Liang, Xiaoyu Chen, Min Su, Hongqiu Chen, Guozhe Lu, Kun Liang · 2014 · Food & Function
34. IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation
    Byounghoon Hwang, Kevin W. McCool, Jun Wan, Shelly M. Wuerzberger‐Davis, Edmond W. K. Young, Eun Young Choi, Gino Cingolani, Beth A. A. Weaver, Shigeki Miyamoto · 2015 · Journal of Biological Chemistry
35. CHIP promotes the activation of NF-κB signaling through enhancing the K63-linked ubiquitination of TAK1
    Yuchun Liu, Yao Sun, Shaoming Han, Yanan Guo, Qingnan Tian, Qiang Ma, Shoutao Zhang · 2021 · Cell Death Discovery
36. Retracted: Inhibiting the PI3K/Akt, NF-κB signalling pathways with syringic acid for attenuating the development of oral squamous cell carcinoma cells SCC131
    Periyannan Velu, Annamalai Vijayalakshmi, Veerasamy Vinothkumar · 2020 · Journal of Pharmacy and Pharmacology · Retracted
37. Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action
    Ali Altıntaş, Jie Liu, Odile Fabre, Tsai‐Der Chuang, Ying Wang, Reiko Sakurai, Galal Nazih Chehabi, Romain Barrès, Virender Kumar Rehan · 2021 · The FASEB Journal
38. Ubiquitin-chains dynamics and its role regulating crucial cellular processes
    María Gonzalez-Santamarta, Corentin Bouvier, Manuel S. Rodríguez, Wendy Xolalpa · 2021 · Seminars in Cell and Developmental Biology
39. Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-κB through a targetable second interaction with upstream activator IKK2
    Myung Soo Ko, Samantha Cohen, Smarajit Polley, Sushil Kumar Mahata, Tapan Biswas, Tom Huxford, Gourisankar Ghosh · 2022 · Journal of Biological Chemistry
40. Comprehensive Investigation into the Role of Ubiquitin-Conjugating Enzyme E2S in Melanoma Development
    Ping Wang, Yong Li, Yangyang Ma, Xiaoyan Zhang, Li Zhao, Wenzhong Yu, Mengyan Zhu, Jiaqi Wang, Yongping Xu, Aie Xu · 2020 · Journal of Investigative Dermatology
41. The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms
    Francesca Felicia Caputi, Lorenzo Di Cesare Mannelli, Laura Rullo, Laura Micheli, Serena Stamatakos, Luca Posa, Carla Ghelardini, Patrizia Romualdi, Sanzio Candeletti · 2020 · Biochemical Pharmacology
42. Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters
    Chaogang Wang, Zhuxiang Jiang, Mingyang Du, Rihao Cong, Wei Wang, Taiping Zhang, Jincheng Chen, Guofan Zhang, Li Li · 2024 · Cell Communication and Signaling
43. Low dose gamma irradiation attenuates cyclophosphamide-induced cardiotoxicity in rats: role of NF-κB signaling pathway
    Amira Abd-ElRaouf, Ahmed S. Nada, Nour El-Din A. Mohammed, H Amer, Sahar S. M. Abdelrahman, Rania M. Abdelsalam, Hesham A. Salem · 2021 · International Journal of Radiation Biology
44. Intrarenal modulation of NF-κB activity attenuates cardiac injury in a swine model of CKD: a renal-cardio axis
    Alejandro Chade, Jason Edward Engel, Michael E. Hall, Alfonso Eirin, Gene Lee Bidwell · 2021 · American Journal of Physiology-Renal Physiology
45. Comparative transcriptome analysis of fast twitch muscle and slow twitch muscle in Takifugu rubripes
    Kailun Gao, Zhicheng Wang, Xiaoxu Zhou, Haoze Wang, Derong Kong, Chen Jiang, Xiuli Wang, Zhiqiang Jiang, Xuemei Qiu · 2017 · Comparative Biochemistry and Physiology Part D Genomics and Proteomics
46. Leuprolide Acetate Inhibits Spinal Cord Inflammatory Response in Experimental Autoimmune Encephalomyelitis by Suppressing NF-κB Activation
    Irene Guzmán-Soto, Eva Salinas, J. Luis Quintanar · 2015 · NeuroImmunoModulation
47. Modulation of the NOD-like receptors NOD1 and NOD2: A chemist’s perspective
    Elizabeth A. D’Ambrosio, Walter R. Drake, Siavash Mashayekh, Ophelia I. Ukaegbu, Ashley R. Brown, Catherine Leimkuhler Grimes · 2019 · Bioorganic & Medicinal Chemistry Letters
48. A single-cell transcriptional roadmap of the mouse and human lymph node lymphatic vasculature
    Menglan Xiang, Rubén Adrián Grosso, Akira Takeda, Junliang Pan, Tove Bekkhus, Kevin Brulois, Denis Đermadi, Sofia Nordling, Michael Vanlandewijck, Sirpa Jalkanen et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
49. Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6
    Wei Cao, Yifei Guo, Zhikui Cheng, Gang Xu, Qi Zuo, Longyu Nie, Yu Huang, Shi Liu, Ying Zhu · 2021 · The Journal of Immunology
50. Involvement of ubiquitination in Alzheimer’s disease
    Nan Lin, Xiyan Gao, Xiao Li, Wen-Ming Chu · 2024 · Frontiers in Neurology
51. Efficient Overcoming of Blood–Brain Barrier by Functionalized Selenium Nanoparticles to Treat Glioma
    Mengqi Chen, Yanyu Huang, Xueqiong Zhu, Xiaoli Hu, Tianfeng Chen · 2018 · Advanced Therapeutics
52. Helium Protects against Lipopolysaccharide-Induced Cardiac Dysfunction in Mice via Suppressing Toll-Like Receptor 4-Nuclear Factor κB-Tumor Necrosis Factor-Alpha/ Interleukin-18 Signaling
    Yaxing Zhang, Jiongshan Zhang, Kangquan Xu, Zifeng Chen, Xiaodan Xu, Jingting Xu, Shuhui Zheng, Min Dai, Hongzhi Yang · 2020 · The Chinese Journal of Physiology
53. Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO
    Han Chen, Xuhong Chen, Zhuojun Zhang, Wenhao Bao, Zhiqing Gao, Difeng Li, Xiaoyi Xie, Ping Zhou, Chunxiao Yang, Zhongqiu Zhou et al. · 2022 · Oncogene
54. Does Antigen Masking by Ubiquitin Chains Protect from the Development of Autoimmune Diseases?
    Robert Weil · 2014 · Frontiers in Immunology
55. Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing
    Chunjie Sheng, Chen Yao, Ziyang Wang, Hong‐Yuan Chen, Yu Zhao, Dazhi Xu, Haojie Huang, Wenlin Huang, Shuai Chen · 2018 · Nature Communications
56. Toll-like Receptor 8 Stability is Regulated by Ring Finger 216 in Response to Circulating MicroRNAs
    John W. Evankovich, Travis Lear, Courtney Baldwin, Yanwen Chen, Virginia White, John J. Villandre, James David Londino, Yuan Liu, Bryan J. McVerry, Georgios D. Kitsios et al. · 2019 · American Journal of Respiratory Cell and Molecular Biology
57. Beyond Host Defense: Deregulation of Drosophila Immunity and Age-Dependent Neurodegeneration
    Srishti Arora, Petros Ligoxygakis · 2020 · Frontiers in Immunology
58. Role of RING-Type E3 Ubiquitin Ligases in Inflammatory Signalling and Inflammatory Bowel Disease
    Liguo Zhu, Ying Li, Longyuan Zhou, Guang Yang, Ying Wang, Jing Han, Li Li, Shenghong Zhang · 2020 · Mediators of Inflammation
59. Eupalinolide B inhibits periodontitis development by targeting ubiquitin conjugating enzyme UBE2D3
    Wenhua Kuang, Ruishen Zhuge, Ping Song, Letai Yi, Shujie Zhang, Ying Zhang, Yin‐Kwan Wong, Ruixing Chen, Junzhe Zhang, Yuanbo Wang et al. · 2025 · MedComm
60. An Integrated View of Deubiquitinating Enzymes Involved in Type I Interferon Signaling, Host Defense and Antiviral Activities
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61. PARK2 Induces Osteoclastogenesis through Activation of the NF-κB Pathway
    Seo Jin Hong, Suhan Jung, Ji Sun Jang, Shenzheng Mo, Jun‐Oh Kwon, Min Kyung Kim, Hong‐Hee Kim · 2022 · Molecules and Cells
62. RBM23 Drives Hepatocellular Carcinoma by Activating NF‐κB Signaling Pathway
    Hexu Han, Ting Lin, Ziyi Fang, Guoxiong Zhou · 2021 · BioMed Research International
63. Advances in the potential roles of Cullin-RING ligases in regulating autoimmune diseases
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64. Ubiquitination of Nonhistone Proteins in Cancer Development and Treatment
    Xiuzhen Zhang, Tong Meng, Shuaishuai Cui, Ling Feng, Dongwu Liu, Qiuxiang Pang, Ping Wang · 2021 · Frontiers in Oncology
65. Therapeutic potential of ginseng leaf extract in inhibiting mast cell-mediated allergic inflammation and atopic dermatitis-like skin inflammation in DNCB-treated mice
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66. Palovarotene inhibits the NF‐κB signalling pathway to prevent heterotopic ossification
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67. Selective monitoring of ubiquitin signals with genetically encoded ubiquitin chain–specific sensors
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68. Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
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69. The RING domain of RING Finger 11 ( RNF 11) protein binds Ubc13 and inhibits formation of polyubiquitin chains
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70. Candidate Genes and Gene Networks Change with Age in Japanese Black Cattle by Blood Transcriptome Analysis
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71. Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks
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72. NFκB-mediated activation of the cellular FUT3, 5 and 6 gene cluster by herpes simplex virus type 1
    Rickard Nordén, Ebba Samuelsson, Kristina Nyström · 2017 · Glycobiology
73. Deubiquitinases as pivotal regulators of T cell functions
    Xiaodong Yang, Shao‐Cong Sun · 2018 · Frontiers of Medicine
74. Pathogenic E. coli HPI upregulate the expression of inflammatory factors in porcine small intestinal epithelial cells by ubiquitin proteasome pathway
    Chaoying Liu, Chunlan Shan, Qin Dong, Guowen Fu, Ru Zhao, Yulin Yan, Hong Gao · 2018 · Research in Veterinary Science
75. Analysis of the topology of ubiquitin chains
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76. Chinese Herbal Formula, Huayu Tongbi Fang, Attenuates Inflammatory Proliferation of Rat Synoviocytes Induced by IL‐1β by Regulating Proliferation and Differentiation of T Lymphocytes
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77. Preparing to read the ubiquitin code: top‐down analysis of unanchored ubiquitin tetramers
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78. The NF-ĸB p50 subunit generated by KPC1-mediated ubiquitination and limited proteasomal processing, suppresses tumor growth
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79. Drug repurposing in the treatment of chronic inflammatory diseases
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80. Emerging Roles of Ubiquitination in Biomolecular Condensates
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81. Tripartite motif‐containing proteins precisely and positively affect host antiviral immune response
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82. Methyl 3,4-dihydroxybenzoate protects against d -galN/LPS-induced acute liver injury by inhibiting inflammation and apoptosis in mice
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83. Loss of Rictor in tubular cells exaggerates lipopolysaccharide induced renal inflammation and acute kidney injury via Yap/Taz-NF-κB axis
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84. TRIM25 Identification in the Chinese Goose: Gene Structure, Tissue Expression Profiles, and Antiviral Immune Responses In Vivo and In Vitro
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85. Human/mouse CD137 agonist, JNU-0921, effectively shrinks tumors through enhancing the cytotoxicity of CD8 + T cells in cis and in trans
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86. Isoleucine 44 Hydrophobic Patch Controls Toxicity of Unanchored, Linear Ubiquitin Chains through NF-κB Signaling
    Jessica R. Blount, Kozeta Libohova, Gustavo M. Silva, Sokol V. Todi · 2020 · Cells
87. Conformational Space Sampled by Domain Reorientation of Linear Diubiquitin Reflected in Its Binding Mode for Target Proteins
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88. Characterization of TRAF2 in Nile tilapia: Expression profiles and the role in decreasing NF-κB pathway
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89. Cyclic-AMP Increases Nuclear Actin Monomer Which Promotes Proteasomal Degradation of RelA/p65 Leading to Anti-Inflammatory Effects
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90. Post-translational Control of Innate Immune Signaling Pathways by Herpesviruses
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91. Reduced IκBα promotes hepatocellular carcinoma cell proliferation and migration via regulation of NF‑κB/Erbin axis
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92. Protective effect of chitosan oligosaccharide against oxidative damage of peripheral blood mononuclear cells in dairy cows induced by diethylenetriamine/nitric oxide via NF-κB signalling pathway
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93. Integrating state-space modeling, parameter estimation, deep learning, and docking techniques in drug repurposing: a case study on COVID-19 cytokine storm
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94. NEMO Family of Proteins as Polyubiquitin Receptors: Illustrating Non-Degradative Polyubiquitination’s Roles in Health and Disease
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95. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution
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96. TAK1 lessens the activity of the paracaspase MALT1 during T cell receptor signaling
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97. Ubiquitination in macrophage plasticity: from inflammatory to immunometabolic pathways
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98. Phytogenic diet enhances the growth and disease resistance of the black-spotted frog, Pelophylax nigromaculatus, by stabilizing intestinal homeostasis and boosting innate immunity
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99. Co-expression analysis identifies neuro-inflammation as a driver of sensory neuron aging in Aplysia californica
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100. The Impact of Induction Regimes on Immune Responses in Patients with Multiple Myeloma
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