Cited by 46Artificial Intelligence in HealthcareParkinson's Disease Mechanisms and TreatmentsVoice and Speech Disorders

Bag of Samplings for computer-assisted Parkinson's disease diagnosis based on Recurrent Neural Networks

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Ribeiro, Luiz C.F., Afonso, Luis C.S., Papa, João P.·2019·Computers in Biology and Medicine

Abstract

Parkinson's Disease (PD) is a clinical syndrome that affects millions of people worldwide. Although considered as a non-lethal disease, PD shortens the life expectancy of the patients. Many studies have been dedicated to evaluating methods for early-stage PD detection, which includes machine learning techniques that employ, in most cases, motor dysfunctions, such as tremor. This work explores the time dependency in tremor signals collected from handwriting exams. To learn such temporal information, we propose a model based on Bidirectional Gated Recurrent Units along with an attention mechanism. We also introduce the concept of "Bag of Samplings" that computes multiple compact representations of the signals. Experimental results have shown the proposed model is a promising technique with results comparable to some state-of-the-art approaches in the literature.

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Crossref · 10.1016/j.compbiomed.2019.103477

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Authors
Ribeiro, L. C. F., Afonso, L. C. S., & Papa, J. P.
Affiliations
  • Universidade Estadual Paulista (Unesp) (BR)
  • Universidade Federal de São Carlos (BR)
Corresponding author
Papa, João P.
Venue
Computers in Biology and Medicine
Publisher
Elsevier BV
Published
2019-12
Volume
115
Pages
103477
ISSN
0010-4825 (ISSN-L)
OpenAlex
W2978080568
Cited by
46
References
1
Citations by year
2026: 3 · 2025: 3 · 2024: 5 · 2023: 10 · 2022: 6 · 2021: 10 · 2020: 7 · 2019: 2
FWCI
6.62
Type
journal article
Language
en
Open access
Locations
  • Computers in Biology and Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
Funders
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico (307066/2017-7, 427968/2018-6)
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (2013/07375-0, 2014/12236-1)
Topics
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
  • Health Sciences › Medicine › Physiology › Voice and Speech Disorders
Keywords
Parkinson's disease diagnosis, handwriting analysis, bidirectional gated recurrent unit, attention mechanism, time series representation
MeSH terms
Machine Learning, Adolescent, Adult, Aged, Diagnosis, Computer-Assisted, Female, Handwriting, Humans, Male, Middle Aged, Parkinson Disease, Neural Networks, Computer

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