Bag of Samplings for computer-assisted Parkinson's disease diagnosis based on Recurrent Neural Networks
Open accessAbstract
Parkinson's Disease (PD) is a clinical syndrome that affects millions of people worldwide. Although considered as a non-lethal disease, PD shortens the life expectancy of the patients. Many studies have been dedicated to evaluating methods for early-stage PD detection, which includes machine learning techniques that employ, in most cases, motor dysfunctions, such as tremor. This work explores the time dependency in tremor signals collected from handwriting exams. To learn such temporal information, we propose a model based on Bidirectional Gated Recurrent Units along with an attention mechanism. We also introduce the concept of "Bag of Samplings" that computes multiple compact representations of the signals. Experimental results have shown the proposed model is a promising technique with results comparable to some state-of-the-art approaches in the literature.
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Voice-based methods and drawing images require patients to have no cognitive disorder and fail in case of low compliance.
“Both voice-based method and drawing images require that the patients have no cognitive disorder and fail to work in case of the low compliance of patients.”
From Detection and Quantification of Resting Tremor in Parkinson's Disease Using Long-Term Acceleration Data (2021) · cites this paper as [7]
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Adam: A Method for Stochastic Optimization
Kingma, D. P., & Ba, J. (2014) · arXiv · doi:10.48550/arxiv.1412.6980 · Cited by 98,946 · see citing works
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Yuan, H., Liu, S., Liu, J., Lin, H., Yang, C., Cai, X., Zeng, L., & Li, S. (2021) · Mathematical Problems in Engineering · doi:10.1155/2021/5669932 · Cited by 10 · see citing works
Evolving Long Short-Term Memory Networks
Lobo Neto, V. C., Passos, L. A., & Papa, J. P. (2020) · Lecture Notes in Computer Science · doi:10.1007/978-3-030-50417-5_25 · Cited by 9 · see citing works
Self-citation
- Authors
- Ribeiro, L. C. F., Afonso, L. C. S., & Papa, J. P.
- Affiliations
- Universidade Estadual Paulista (Unesp) (BR)
- Universidade Federal de São Carlos (BR)
- Corresponding author
- Papa, João P.
- Venue
- Computers in Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2019-12
- Volume
- 115
- Pages
- 103477
- ISSN
- 0010-4825 (ISSN-L)
- OpenAlex
- W2978080568
- Cited by
- 46
- References
- 1
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 5 · 2023: 10 · 2022: 6 · 2021: 10 · 2020: 7 · 2019: 2
- FWCI
- 6.62
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Computers in Biology and Medicine (publishedVersion)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
- Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (307066/2017-7, 427968/2018-6)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2013/07375-0, 2014/12236-1)
- Topics
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Physiology › Voice and Speech Disorders
- Keywords
- Parkinson's disease diagnosis, handwriting analysis, bidirectional gated recurrent unit, attention mechanism, time series representation
- MeSH terms
- Machine Learning, Adolescent, Adult, Aged, Diagnosis, Computer-Assisted, Female, Handwriting, Humans, Male, Middle Aged, Parkinson Disease, Neural Networks, Computer
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