Auditory cortical plasticity in cochlear implant users.
Open accessAbstract
Cochlear implants are one of the most successful neuroprosthetic devices that have been developed to date. Profoundly deaf patients can achieve speech perception after complete loss of sensory input. Despite the improvements many patients experience, there is still a large degree of outcome variability. It has been proposed that central plasticity may be a major factor in the different levels of benefit that patients experience. However, the neural mechanisms of how plasticity impacts cochlear implant learning and the degree of plasticity's influence remain unknown. Here, we review the human and animal research on three of the main ways that central plasticity affects cochlear implant outcomes.
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Auditory prostheses have already allowed many deaf patients to hear sounds and acquire language capabilities.
“These devices have already allowed many deaf patients to hear sounds and acquire language capabilities (Merkus et al., 2014; Glennon et al., 2019), and the same hope exists in the field of neuroprosthetic devices designed for electrical stimulation of the visual cortex.”
From Toward Long-Term Communication With the Brain in the Blind by Intracortical Stimulation: Challenges and Future Prospects (2020) · cites this paper as Glennon et al., 2019
Neuroplasticity implies that the brain undergoes important remodeling and adaptive changes after the onset of blindness that could directly impact the success of any cortical prosthesis.
“This neuroplasticity implies that the brain undergoes important remodeling and adaptive changes after the onset of the blindness that could directly impact the success of any cortical prosthesis (Glennon et al., 2019).”
From Toward Long-Term Communication With the Brain in the Blind by Intracortical Stimulation: Challenges and Future Prospects (2020) · cites this paper as Glennon et al., 2019
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- Authors
- Glennon, E., Svirsky, M. A., & Froemke, R. C.
- Affiliations
- NYU Langone Health (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Svirsky, Mario A
- Froemke, Robert C
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 60
- Pages
- 108-114
- ISSN
- 0959-4388 (ISSN-L)
- PMC
- PMC7002179
- OpenAlex
- W2995831580
- Cited by
- 81
- References
- 70
- Citations by year
- 2026: 9 · 2025: 16 · 2024: 14 · 2023: 16 · 2022: 11 · 2021: 9 · 2020: 5 · 2018: 1
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Current Opinion in Neurobiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institute on Deafness and Other Communication Disorders
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hearing Loss and Rehabilitation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Life Sciences › Neuroscience › Sensory Systems › Hearing, Cochlea, Tinnitus, Genetics
- Keywords
- cochlear implants, central plasticity, profound hearing loss, speech perception, neuroprosthetics, outcome variability, auditory cortex, animal models
- MeSH terms
- Animals, Auditory Cortex, Cochlear Implants, Deafness, Humans, Neuronal Plasticity, Speech Perception, Cochlear Implantation
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