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Mixed culture biotechnology for bioenergy production
Abstract
Mixed culture biotechnology (MCB) could become an attractive addition or alternative to traditional pure culture based biotechnology for the production of chemicals and/or bioenergy. On the basis of ecological selection principles, MCB-based processes can be established that generate a narrow product spectrum from a mixed substrate. Three example processes are briefly discussed in this paper: anaerobic digestion aimed at the production of methane-containing biogas, mixed culture fermentation for the production of solvents or biohydrogen, and a two-step process for the production of polyhydroxyalkanoates. These examples give an idea of the potential contribution of mixed culture biotechnology to sustainable production of bioenergy from waste.
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“Mixed cultures leverage species diversity [127], enabling adaptation to varying light, temperature, and pH conditions [128].”
From A Review of Algae-Based Carbon Capture, Utilization, and Storage (Algae-Based CCUS) (2024) · cites this paper as [127]
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Self-citationImpact of phosphate limitation on PHA production in a feast-famine process
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Electrochemically Driven Fermentation of Organic Substrates with Undefined Mixed Microbial Cultures
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Metadata
- Authors
- Kleerebezem, R., & van Loosdrecht, M. C.
- Affiliations
- Delft University of Technology (NL)
- Corresponding author
- Kleerebezem, Robbert
- ORCID
- Kleerebezem, Robbert
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2007-06
- Volume
- 18
- Issue
- 3
- Pages
- 207-212
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W2031663630
- Cited by
- 624
- References
- 34
- Citations by year
- 2026: 18 · 2025: 15 · 2024: 33 · 2023: 34 · 2022: 39 · 2021: 38 · 2020: 43 · 2019: 49 · 2018: 42 · 2017: 43 · 2016: 48 · 2015: 39 · 2014: 35 · 2013: 30 · 2012: 24
- FWCI
- 5.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Anaerobic Digestion and Biogas Production
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Keywords
- bioenergy production, anaerobic digestion, biogas, methane production, mixed culture fermentation, biohydrogen, solvents, polyhydroxyalkanoates, waste valorization, ecological selection
- MeSH terms
- Anaerobiosis, Biotechnology, Fermentation, Hydrocarbons, Hydrogen, Solvents
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