The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
To engraft or not to engraft: an ecological framework for gut microbiome modulation with live microbes
Open accessAbstract
Strategies aimed at modulating the gut microbiota by using live microbes range from single strains (probiotics or live biotherapeutics) to whole non-defined fecal transplants. Although often clinically efficacious, our understanding on how microbial-based strategies modulate gut microbiome composition and function is vastly incomplete. In this review, we present a framework based on ecological theory that provides mechanistic explanations for the findings obtained in studies that attempted to modulate the gut microbiota of humans and animals using live microbes. We argue that an ecological perspective grounded in theory is necessary to interpret, design, and predict the impact of microbiome-modulating strategies and thus advance our ability to develop novel and improved approaches with enhanced therapeutic efficiency.
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Cites
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Self-citationJacquemont, S., Curie, A., des Portes, V., Torrioli, M. G., Berry-Kravis, E., Hagerman, R. J., Ramos, F. J., Cornish, K., He, Y., Paulding, C., et al. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3001708 · Cited by 609
Fate, activity, and impact of ingested bacteria within the human gut microbiota
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Experimental Evaluation of Host Adaptation of Lactobacillus reuteri to Different Vertebrate Species
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Role of the gut microbiota in nutrition and health
Valdes, A. M., Walter, J., Segal, E., & Spector, T. D. (2018) · BMJ · doi:10.1136/bmj.k2179 · Cited by 2,375
Self-citationWalter, J., Armet, A. M., Finlay, B. B., & Shanahan, F. (2020) · Cell · doi:10.1016/j.cell.2019.12.025 · Cited by 596
Self-citationThe role of the microbiota in infectious diseases
Libertucci, J., & Young, V. B. (2018) · Nature Microbiology · doi:10.1038/s41564-018-0278-4 · Cited by 357
Krumbeck, J. A., Rasmussen, H. E., Hutkins, R. W., Clarke, J., Shawron, K., Keshavarzian, A., & Walter, J. (2018) · Microbiome · doi:10.1186/s40168-018-0494-4 · Cited by 342
Self-citationMocanu, V., Zhang, Z., Deehan, E. C., Kao, D. H., Hotte, N., Karmali, S., Birch, D. W., Samarasinghe, K. K., Walter, J., & Madsen, K. L. (2021) · Nature Medicine · doi:10.1038/s41591-021-01399-2 · Cited by 328
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Metadata
- Authors
- Walter, J., Maldonado-Gómez, M. X., & Martínez, I.
- Venue
- Current Opinion in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2018-02
- Volume
- 49
- Pages
- 129-139
- ISSN
- 0958-1669 (ISSN-L)
- OpenAlex
- W2754193828
- Cited by
- 194
- References
- 10
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
