Cited by 933Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesNeural and Behavioral Psychology StudiesTreatment of Major Depression

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A meta-analysis of emotional reactivity in major depressive disorder

Bylsma, Lauren M., Morris, Bethany H., Rottenberg, Jonathan·2008·Clinical Psychology Review

DOI 10.1016/j.cpr.2007.10.001

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Abstract

Three alternative views regarding how Major Depressive Disorder (MDD) alters emotional reactivity have been featured in the literature: positive attenuation (reduced positive reactivity), negative potentiation (increased negative reactivity), and emotion context insensitivity (ECI; reduced positive and negative reactivity). Although empirical studies have accumulated on emotional reactivity in MDD, this report is to our knowledge the first systematic quantitative review of this topic area. In omnibus analyses of 19 laboratory studies comparing the emotional reactivity of healthy individuals to that of individuals with MDD, MDD was characterized by reduced emotional reactivity to both positively and negatively valenced stimuli, with the reduction larger for positive stimuli (d=-.53) than for negative stimuli (d=-.25). Results were similar when 3 major emotion response systems (self-reported experience, expressive behavior, and peripheral physiology) were analyzed individually. The ECI view of emotional reactivity in MDD is well supported by laboratory data. Implications for the understanding of emotions in MDD are discussed.

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Authors: Bylsma, L. M., Morris, B. H., & Rottenberg, J.
Affiliations: University of South Florida (US)
Corresponding author: Rottenberg, Jonathan
ORCID: Bylsma, Lauren M.
Rottenberg, Jonathan
Venue: Clinical Psychology Review
Publisher: Elsevier BV
Published: 2008-04
Volume: 28
Issue: 4
Pages: 676-691
ISSN: 0272-7358 (ISSN-L)
DOI: 10.1016/j.cpr.2007.10.001
OpenAlex: W2035505019
Cited by: 933
References: 133
Citations by year: 2026: 45 · 2025: 60 · 2024: 62 · 2023: 64 · 2022: 43 · 2021: 77 · 2020: 73 · 2019: 68 · 2018: 63 · 2017: 59 · 2016: 59 · 2015: 63 · 2014: 45 · 2013: 48 · 2012: 30
FWCI: 2.70
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Clinical Psychology Review (publishedVersion)
PubMed (publishedVersion)
Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Keywords: major depressive disorder, emotional reactivity, expressive behavior
MeSH terms: Affect, Major Depressive Disorder, Humans

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A meta-analysis of emotional reactivity in major depressive disorder

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