The DOI matches its Crossref record; 180 of the 180 references it cites were found in a registry or an index.
Long walk to genomics: History and current approaches to genome sequencing and assembly
Open accessAbstract
Genomes represent the starting point of genetic studies. Since the discovery of DNA structure, scientists have devoted great efforts to determine their sequence in an exact way. In this review we provide a comprehensive historical background of the improvements in DNA sequencing technologies that have accompanied the major milestones in genome sequencing and assembly, ranging from early sequencing methods to Next-Generation Sequencing platforms. We then focus on the advantages and challenges of the current technologies and approaches, collectively known as Third Generation Sequencing. As these technical advancements have been accompanied by progress in analytical methods, we also review the bioinformatic tools currently employed in de novo genome assembly, as well as some applications of Third Generation Sequencing technologies and high-quality reference genomes.
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Jarvis, E. D., Formenti, G., Rhie, A., Guarracino, A., Yang, C., Wood, J., Tracey, A., Thibaud-Nissen, F., Vollger, M. R., Porubsky, D., et al. (2022) · Nature · doi:10.1038/s41586-022-05325-5 · Cited by 209
Self-citationMicroalgae with Artificial Intelligence: A Digitalized Perspective on Genetics, Systems and Products
Teng, S. Y., Yew, G. Y., Sukačová, K., Show, P. L., Máša, V., & Chang, J.-S. (2020) · Biotechnology Advances · doi:10.1016/j.biotechadv.2020.107631 · Cited by 145
Computational methods for chromosome-scale haplotype reconstruction
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Metadata
- Authors
- Giani, A. M., Gallo, G. R., Gianfranceschi, L., & Formenti, G.
- Venue
- Computational and Structural Biotechnology Journal
- Published
- 2020
- Volume
- 18
- Pages
- 9-19
- ISSN
- 2001-0370 (ISSN-L)
- OpenAlex
- W2988628263
- Cited by
- 304
- References
- 180
- FWCI
- 9.45
- Type
- journal article
- Language
- en
- Open access
- gold
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