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Cited by 357

The DOI matches its Crossref record; 121 of the 121 references it cites were found in a registry or an index.

Network analysis methods for studying microbial communities: A mini review

Open access
Matchado, Monica Steffi, Lauber, Michael, Reitmeier, Sandra, Kacprowski, Tim, Baumbach, Jan, Haller, Dirk, List, Markus·2021·Computational and Structural Biotechnology Journal

Abstract

Microorganisms including bacteria, fungi, viruses, protists and archaea live as communities in complex and contiguous environments. They engage in numerous inter- and intra- kingdom interactions which can be inferred from microbiome profiling data. In particular, network-based approaches have proven helpful in deciphering complex microbial interaction patterns. Here we give an overview of state-of-the-art methods to infer intra-kingdom interactions ranging from simple correlation- to complex conditional dependence-based methods. We highlight common biases encountered in microbial profiles and discuss mitigation strategies employed by different tools and their trade-off with increased computational complexity. Finally, we discuss current limitations that motivate further method development to infer inter-kingdom interactions and to robustly and comprehensively characterize microbial environments in the future.

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Metadata

Authors
Matchado, M. S., Lauber, M., Reitmeier, S., Kacprowski, T., Baumbach, J., Haller, D., & List, M.
Venue
Computational and Structural Biotechnology Journal
Published
2021
Volume
19
Pages
2687-2698
ISSN
2001-0370 (ISSN-L)
OpenAlex
W3158506552
Cited by
357
References
121
FWCI
24.98
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Network analysis methods for studying microbial communities: A mini review. https://app.cochat.ai/papers/10.1016/j.csbj.2021.05.001
The paper
Matchado, M. S., Lauber, M., Reitmeier, S., Kacprowski, T., Baumbach, J., Haller, D., & List, M. (2021). Network analysis methods for studying microbial communities: A mini review. Computational and Structural Biotechnology Journal. https://doi.org/10.1016/j.csbj.2021.05.001

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.