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Filling the gap between traditional Chinese medicine and modern medicine, are we heading to the right direction?
Abstract
Traditional Chinese medicine (TCM), the ancient medicine popular in China and surrounding areas, has been recognized as a typical representative of complementary and alternative medicine. Over long period in clinical practice, especially the progress in basic research, data on the effectiveness and beneficial contribution of TCM herbs to public health and disease control have been accumulated while the quality of the evidence is generally poor. The most common clinical practice of TCM herbs is herb combination called formula which consists of several types of medicinal herbs or minerals, which is quite different from modern medicine. Definitely, tens of hundreds of compounds could be identified in even a small formula. With the regained enthusiasm on natural products based new drug R&D, the proposed multi-target drug discovery strategy, the booming of -omics technologies, and the implementation of ambitious plan of TCM modernization in China, attempts have been made to fill the gap between TCM herbs and modern drugs. However, are we heading to the right direction?
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To date, conceptual frameworks such as systems biology, pharmacogenomics, and 'omics' technologies have not resulted in marketable products.
“But to date these conceptual frameworks have not resulted in marketable products, leading X. Chen, Pei, and Lu to observe that it is 'embarrassing' that Chinese medicine has been unable to make 'any key breakthroughs despite using such technologies.'”
From Indian Imaginaries of Chinese Success in the Global Herbal Medicine Market: A Critical Assessment (2019) · cites this paper as X. Chen, Pei, and Lu 2013 273-74
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Metadata
- Authors
- Chen, X., Pei, L., & Lu, J.
- Affiliations
- University of Macau (MO)
- Shanghai University of Traditional Chinese Medicine (CN)
- Corresponding author
- Chen, Xiuping
- Venue
- Complementary Therapies in Medicine
- Publisher
- Elsevier BV
- Published
- 2013-06
- Volume
- 21
- Issue
- 3
- Pages
- 272-275
- ISSN
- 0965-2299 (ISSN-L)
- OpenAlex
- W2133304607
- Cited by
- 27
- References
- 32
- Citations by year
- 2023: 2 · 2022: 2 · 2021: 2 · 2020: 4 · 2019: 7 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 4 · 2013: 1
- FWCI
- 6.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Complementary Therapies in Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Studies
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Analysis
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Clinical Research
- Keywords
- traditional Chinese medicine, herbal formula, multi-target drug discovery, natural product drug development, omics technologies, TCM modernization, quality of evidence, complementary and alternative medicine
- MeSH terms
- China, Delivery of Health Care, Drug Combinations, Drugs, Chinese Herbal, Humans, Medicine, Chinese Traditional, Phytotherapy, Plants, Medicinal, Research
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