The DOI matches its Crossref record.
Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses
Open accessOverview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 27
- Richmond, 1999, UNC-13 is required for synaptic vesicle fusion in C. elegans, Nat. Neurosci., 2, 959, 10.1038/14755 · DOI · Paper page
- Richmond, 1999, One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction, Nat. Neurosci., 2, 791, 10.1038/12160 · DOI · Paper page
- Nagel, 2003, Channelrhodopsin-2, a directly light-gated cation-selective membrane channel, Proc. Natl. Acad. Sci. USA, 100, 13940, 10.1073/pnas.1936192100 · DOI · Paper page
- Nagel, 2002, Channelrhodopsin-1: A light-gated proton channel in green algae, Science, 296, 2395, 10.1126/science.1072068 · DOI · Paper page
- Oesterhelt, 1971, Rhodopsin-like protein from the purple membrane of Halobacterium halobium, Nat. New Biol., 233, 149, 10.1038/newbio233149a0 · DOI · Paper page
- Huang, 1994, Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans, Nature, 367, 467, 10.1038/367467a0 · DOI · Paper page
- Butt, 1989, Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump, EMBO J., 8, 1657, 10.1002/j.1460-2075.1989.tb03556.x · DOI
- Boyden, 2005, Millisecond-timescale, genetically targeted optical control of neural activity, Nat. Neurosci., 8, 1263, 10.1038/nn1525 · DOI · Paper page
- Bargmann, 1998, Neurobiology of the Caenorhabditis elegans genome, Science, 282, 2028, 10.1126/science.282.5396.2028 · DOI · Paper page
- Yuan, 2003, The sodium-activated potassium channel is encoded by a member of the Slo gene family, Neuron, 37, 765, 10.1016/S0896-6273(03)00096-5 · DOI · Paper page
- Yuan, 2000, SLO-2, a K+ channel with an unusual Cl- dependence, Nat. Neurosci., 3, 771, 10.1038/77670 · DOI
- Lee, 1997, Mutations in the alpha1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegans, EMBO J., 16, 6066, 10.1093/emboj/16.20.6066 · DOI · Paper page
- Mathews, 2003, Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties, J. Neurosci., 23, 6537, 10.1523/JNEUROSCI.23-16-06537.2003 · DOI
- Schafer, 1995, A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans, Nature, 375, 73, 10.1038/375073a0 · DOI · Paper page
- Maryon, 1996, unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction, J. Cell Biol., 134, 885, 10.1083/jcb.134.4.885 · DOI
- Ernstrom, 2002, Genetics of sensory mechanotransduction, Annu. Rev. Genet., 36, 411, 10.1146/annurev.genet.36.061802.101708 · DOI
- Wittenburg, 1999, Thermal avoidance in Caenorhabditis elegans: An approach to the study of nociception, Proc. Natl. Acad. Sci. USA, 96, 10477, 10.1073/pnas.96.18.10477 · DOI · Paper page
- Burr, 1985, The photomovement of Caenorhabditis elegans, a nematode which lacks ocelli. Proof that the response is to light not radiant heating, Photochem. Photobiol., 41, 577, 10.1111/j.1751-1097.1985.tb03529.x · DOI
- Rankin, 1990, Caenorhabditis elegans: A new model system for the study of learning and memory, Behav. Brain Res., 37, 89, 10.1016/0166-4328(90)90074-O · DOI · Paper page
- O'Hagan, 2005, The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals, Nat. Neurosci., 8, 43, 10.1038/nn1362 · DOI · Paper page
- Suzuki, 2003, In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation, Neuron, 39, 1005, 10.1016/j.neuron.2003.08.015 · DOI · Paper page
- Bianchi, 2004, The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: Implications for necrosis initiation, Nat. Neurosci., 7, 1337, 10.1038/nn1347 · DOI
- Chalfie, 1981, Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans, Dev. Biol., 82, 358, 10.1016/0012-1606(81)90459-0 · DOI · Paper page
- Shimono, 2003, Importance of the broad regional interaction for spectral tuning in Natronobacterium pharaonis phoborhodopsin (sensory rhodopsin II), J. Biol. Chem., 278, 23882, 10.1074/jbc.M301200200 · doi:10.1074/jbc.m301200200
- Bargmann, 1995, Laser killing of cells in Caenorhabditis elegans, Methods Cell Biol., 48, 225, 10.1016/S0091-679X(08)61390-4 · DOI · Paper page
- Tobin, 2002, Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons, Neuron, 35, 307, 10.1016/S0896-6273(02)00757-2 · DOI · Paper page
- Lima, 2005, Remote control of behavior through genetically targeted photostimulation of neurons, Cell, 121, 141, 10.1016/j.cell.2005.02.004 · DOI · Paper page
Cited by
Independent optical excitation of distinct neural populations
Klapoetke, N. C., Murata, Y., Kim, S. S., Pulver, S. R., Birdsey-Benson, A., Cho, Y. K., Morimoto, T. K., Chuong, A. S., Carpenter, E. J., Tian, Z., et al. (2014) · Nature Methods · doi:10.1038/nmeth.2836 · Cited by 2,344
Optogenetics in neural systems
Yizhar, O., Fenno, L. E., Davidson, T. J., Mogri, M., & Deisseroth, K. (2011) · Neuron · doi:10.1016/j.neuron.2011.06.004 · Cited by 1,881
The development and application of optogenetics
Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113817 · Cited by 1,822
A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
Madisen, L., Mao, T., Koch, H., Zhuo, J.-M., Berenyi, A., Fujisawa, S., Hsu, Y.-W. A., Garcia, A. J., Gu, X., Zanella, S., et al. (2012) · Nature Neuroscience · doi:10.1038/nn.3078 · Cited by 1,398
Neural substrates of awakening probed with optogenetic control of hypocretin neurons
Adamantidis, A. R., Zhang, F., Aravanis, A. M., Deisseroth, K., & de Lecea, L. (2007) · Nature · doi:10.1038/nature06310 · Cited by 1,341
Metadata
- Authors
- Nagel, G., Brauner, M., Liewald, J. F., Adeishvili, N., Bamberg, E., & Gottschalk, A.
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 2005-12
- Volume
- 15
- Issue
- 24
- Pages
- 2279-2284
- ISSN
- 0960-9822 (ISSN-L)
- OpenAlex
- W2127183925
- Cited by
- 1,001
- References
- 0
- FWCI
- 6.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 2785 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses. https://app.cochat.ai/papers/10.1016/j.cub.2005.11.032
- The paper
- Nagel, G., Brauner, M., Liewald, J. F., Adeishvili, N., Bamberg, E., & Gottschalk, A. (2005). Light Activation of Channelrhodopsin-2 in Excitable Cells of Caenorhabditis elegans Triggers Rapid Behavioral Responses. Current Biology. https://doi.org/10.1016/j.cub.2005.11.032
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.