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ARF6 Interacts with JIP4 to Control a Motor Switch Mechanism Regulating Endosome Traffic in Cytokinesis
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JIP4 is a large scaffold that binds both dynein and kinesin-1.
“JIP4 is a large scaffold that binds both dynein and, notably, also kinesin-1, which mediates anterograde organelle transport (Celestino et al., 2022;Montagnac et al., 2009;Nguyen et al., 2005;Verhey et al., 2001;Vilela et al., 2019).”
From TMEM55B promotes anterograde transport and distal axonal distribution of LAMP1-positive organelles (2026) · cites this paper as Montagnac et al., 2009
The Results describe JIP4 as a scaffolding protein and show that it binds kinesin-1. They show JIP4 interacting with the dynactin complex, however, not binding dynein itself; the dynein observation in the retrieved Results concerns JIP3. (LLM, conf=0.87)
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Cites
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3
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Cited by
Sorted by citations
Willett, R., Martina, J. A., Zewe, J. P., Wills, R., Hammond, G. R. V., & Puertollano, R. (2017) · Nature Communications · doi:10.1038/s41467-017-01871-z · Cited by 201
Matsui, T., Ohbayashi, N., & Fukuda, M. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.370544 · Cited by 90
TMEM55B promotes anterograde transport and distal axonal distribution of LAMP1-positive organelles
Rudnik, S., Li, C. H., Gottschling, D.-C., Veh, A., Barbosa, D. J., Richter, J., Stroobants, S., Schuster, B., Beck, I. M., Sedlack, R., et al. (2026) · doi:10.64898/2026.10.27.762112
Metadata
- Authors
- Montagnac, G., Sibarita, J.-B., Loubéry, S., Daviet, L., Romao, M., Raposo, G., & Chavrier, P.
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 19
- Issue
- 3
- Pages
- 184-195
- ISSN
- 0960-9822
- Cited by
- 206
- References
- 1
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 1627 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
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