Long-lived effects of administering β-glucans: Indications for trained immunity in fish
Open accessAbstract
Over the past decades, it has become evident that immune-modulation of fish with β-glucans, using injection, dietary or even immersion routes of administration, has stimulating but presumed short-lived effects on both intestinal and systemic immunity and can increase protection against a subsequent pathogenic challenge. Although the exact effects can be variable depending on, among others, fish species and administration route, the immune-stimulating effects of β-glucans on the immune system of fish appear to be universal. This review provides a condensed update of the most recent literature describing the effects of β-glucans on the teleost fish immune system. We shortly discuss possible mechanisms influencing immune-stimulation by β-glucans, including microbial composition of the gut, receptor recognition and downstream signalling. Of interest, in mammalian monocytes, β-glucans are potent inducers of trained immunity. First, we screened the literature for indications of this phenomenon in fish. Criteria that we applied include indications for at least one out of three features considered characteristic of trained immunity; (i) providing protection against a secondary infection in a T- and B-lymphocyte independent manner, (ii) conferring increased resistance upon re-infection and, (iii) relying on key roles for innate immune cell types such as natural killer cells and macrophages. We conclude that several indications exist that support the notion that the innate immune system of teleost fish can be trained. Second, we screened the literature for indications of long-lived effects on innate immunity of fish after administering β-glucans, a criterion which could help to identify key roles for macrophages on resistance to infection. We discuss whether β-glucans, as well-known immune-stimulants, are able to train the immune system of fish and argue in favour of further studies designed to specifically investigate this phenomenon in fish.
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Beta glucan is a well-documented immune stimulant in fish.
“Beta glucan is also a well-documented immune stimulant in fish (reviewed in [15])”
From Trained Immunity Provides Long-Term Protection against Bacterial Infections in Channel Catfish (2022) · cites this paper as [15]
Cites
Pathogen Recognition and Innate Immunity
Akira, S., Uematsu, S., & Takeuchi, O. (2006) · Cell · doi:10.1016/j.cell.2006.02.015 · Cited by 11,974 · see citing works
Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.083001.084359 · Cited by 8,394 · see citing works
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
Cheng, S.-C., Quintin, J., Cramer, R. A., Shepardson, K. M., Saeed, S., Kumar, V., Giamarellos-Bourboulis, E. J., Martens, J. H. A., Rao, N. A., Aghajanirefah, A., et al. (2014) · Science · doi:10.1126/science.1250684 · Cited by 2,224 · see citing works
Innate immunity of fish (overview).
Magnadóttir, B. (2006) · Fish and Shellfish Immunology · doi:10.1016/j.fsi.2004.09.006 · Cited by 2,203 · see citing works
Ryals, J. A., Neuenschwander, U. H., Willits, M. G., Molina, A., Steiner, H., & Hunt, D. M. (1996) · The Plant Cell · doi:10.1105/tpc.8.10.1809 · Cited by 2,060 · see citing works
Kleinnijenhuis, J., Quintin, J., Preijers, F., Joosten, L. A. B., Ifrim, D. C., Saeed, S., Jacobs, C., van Loenhout, J., de Jong, D., Stunnenberg, H. G., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1202870109 · Cited by 1,728 · see citing works
Trained Immunity: A Memory for Innate Host Defense
Netea, M. G., Quintin, J., & van der Meer, J. W. M. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.04.006 · Cited by 1,697 · see citing works
Quintin, J., Saeed, S., Martens, J. H. A., Giamarellos-Bourboulis, E. J., Ifrim, D. C., Logie, C., Jacobs, L., Jansen, T., Kullberg, B.-J., Wijmenga, C., et al. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.06.006 · Cited by 1,289 · see citing works
Ryals, J. A., Neuenschwander, U. H., Willits, M. G., Molina, A., Steiner, H., & Hunt, M. D. (1996) · The Plant Cell · doi:10.2307/3870231 · Cited by 1,109 · see citing works
Siwicki, A. K., Anderson, D. P., & Rumsey, G. L. (1994) · Veterinary Immunology and Immunopathology · doi:10.1016/0165-2427(94)90062-0 · Cited by 813 · see citing works
The mucosal immune system of fish: The evolution of tolerating commensals while fighting pathogens
Gómez, D., Sunyer, J. O., & Salinas, I. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.09.032 · Cited by 800 · see citing works
β‐glucan recognition by the innate immune system
Goodridge, H. S., Wolf, A. J., & Underhill, D. M. (2009) · Immunological Reviews · doi:10.1111/j.1600-065x.2009.00793.x · Cited by 693 · see citing works
Kleinnijenhuis, J., Quintin, J., Preijers, F. W. M. B., Benn, C. S., Joosten, L. A. B., Jacobs, C. W. M., van Loenhout, J., Xavier, R. J., Aaby, P., van der Meer, J. W. M., et al. (2013) · Journal of Innate Immunity · doi:10.1159/000355628 · Cited by 625 · see citing works
The Mucosal Immune System of Teleost Fish
Salinas, I. (2015) · Biology · doi:10.3390/biology4030525 · Cited by 522 · see citing works
Beta-glucan: an ideal immunostimulant in aquaculture (a review)
Meena, D. K., Das, P., Kumar, S., Mandal, S. C., Prusty, A. K., Singh, S. K., Akhtar, M. S., Behera, B. K., Kumar, K., Pal, A. K., et al. (2012) · Fish Physiology and Biochemistry · doi:10.1007/s10695-012-9710-5 · Cited by 468 · see citing works
Specific memory within innate immune systems
Kurtz, J. (2005) · Trends in Immunology · doi:10.1016/j.it.2005.02.001 · Cited by 394 · see citing works
Non-digestible Oligosaccharides with Prebiotic Properties
Swennen, K., Courtin, C. M., & Delcour, J. A. (2006) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390500215746 · Cited by 346 · see citing works
ß-glucans as conductors of immune symphonies
Dalmo, R. A., & Bøgwald, J. (2008) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2008.04.008 · Cited by 342 · see citing works
Epigenetic control of myeloid cell differentiation, identity and function
Álvarez‐Errico, D., Vento‐Tormo, R., Sieweke, M. H., & Ballestar, E. (2014) · Nature reviews. Immunology · doi:10.1038/nri3777 · Cited by 328 · see citing works
Conrath, U. (2006) · Plant Signaling & Behavior · doi:10.4161/psb.1.4.3221 · Cited by 319 · see citing works
Effects of beta-glucans on the immune system.
Akramienė, D., Kondrotas, A. J., Didžiapetrienė, J., & Kėvelaitis, E. (2007) · PubMed · Cited by 297 · see citing works
Robertsen, B., RΘRSTAD, G., Engstad, R. E., & Raa, J. (1990) · Journal of Fish Diseases · doi:10.1111/j.1365-2761.1990.tb00798.x · Cited by 271 · see citing works
Innate immune memory: a paradigm shift in understanding host defense
Netea, M. G., Latz, E., Mills, K. H. G., & O'Neill, L. A. J. (2015) · Nature Immunology · doi:10.1038/ni.3178 · Cited by 269 · see citing works
CHEN, D., & AINSWORTH, A. J. (1992) · Journal of Fish Diseases · doi:10.1111/j.1365-2761.1992.tb00667.x · Cited by 218 · see citing works
Ligand specificities of Toll-like receptors in fish: Indications from infection studies
Pietretti, D., & Wiegertjes, G. F. (2013) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2013.08.010 · Cited by 215 · see citing works
Self-citationJeney, G., Galeotti, M., Volpatti, D., Jeney, Z., & Anderson, D. P. (1997) · Aquaculture · doi:10.1016/s0044-8486(97)00042-2 · Cited by 210 · see citing works
Kawashima, T., Kosaka, A., Yan, H., Guo, Z., Uchiyama, R., Fukui, R., Kaneko, D., Kumagai, Y., You, D., Carreras, J., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.02.024 · Cited by 206 · see citing works
Beta-glucans as immunostimulant in vertebrates and invertebrates
Soltanian, S., Stuyven, E., Cox, E., Sorgeloos, P., & Bossier, P. (2009) · Critical Reviews in Microbiology · doi:10.1080/10408410902753746 · Cited by 202 · see citing works
Refstie, S., Bæverfjord, G., Seim, R. R., & Elvebø, O. (2010) · Aquaculture · doi:10.1016/j.aquaculture.2010.04.005 · Cited by 198 · see citing works
Lin, S., Pan, Y., Luo, L., & Luo, L. (2011) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.07.013 · Cited by 196 · see citing works
Training innate immunity: the changing concept of immunological memory in innate host defence
Netea, M. G. (2013) · European Journal of Clinical Investigation · doi:10.1111/eci.12132 · Cited by 195 · see citing works
Vernooij, B. (1995) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi-8-0228 · Cited by 184 · see citing works
Effect of a yeast-cell-wall glucan on the bactericidal activity of rainbow trout macrophages
Jørgensen, J. B., Sharp, G. J. E., Secombes, C. J., & Robertsen, B. (1993) · Fish & Shellfish Immunology · doi:10.1006/fsim.1993.1026 · Cited by 183 · see citing works
Non-digestible long chain beta-glucans as novel prebiotics
Lam, K., & Cheung, P. C. K. (2013) · Bioactive Carbohydrates and Dietary Fibre · doi:10.1016/j.bcdf.2013.09.001 · Cited by 182 · see citing works
El‐Boshy, M., El‐Ashram, A., Abdelhamid, F., & Gadalla, H. (2010) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2010.01.017 · Cited by 177 · see citing works
Dawood, M. A. O., Koshio, S., Ishikawa, M., & Yokoyama, S. (2015) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2015.01.033 · Cited by 172 · see citing works
Evolution of effectors and receptors of innate immunity
Magor, B. G., & Magor, K. E. (2001) · Developmental & Comparative Immunology · doi:10.1016/s0145-305x(01)00029-5 · Cited by 166 · see citing works
Polarization of immune responses in fish: The ‘macrophages first’ point of view
Wiegertjes, G. F., Wentzel, A. S., Spaink, H. P., Elks, P. M., & Fink, I. R. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.09.026 · Cited by 163 · see citing works
Self-citationYeast β-glucan stimulates respiratory burst activity of Atlantic salmon (Salmo salar L.) macrophages
Jørgensen, J. B., & Robertsen, B. (1995) · Developmental & Comparative Immunology · doi:10.1016/0145-305x(94)00045-h · Cited by 160 · see citing works
Immunomodulation by dietary vitamin C and glucan in rainbow trout (Oncorhynchus mykiss)
Verlhac-Trichet, V., Obach, A., Gabaudan, J., Schüep, W., & Hole, R. (1998) · Fish & Shellfish Immunology · doi:10.1006/fsim.1998.0148 · Cited by 157 · see citing works
van der Marel, M., Adamek, M., González, S., Frost, P., Rombout, J. H. W. M., Wiegertjes, G. F., Savelkoul, H. F. J., & Steinhagen, D. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2011.12.008 · Cited by 156 · see citing works
Self-citationCarda‐Diéguez, M., Mira, Á., & Fouz, B. (2013) · FEMS Microbiology Ecology · doi:10.1111/1574-6941.12236 · Cited by 139 · see citing works
Selvaraj, V., Sampath, K., & Sekar, V. (2006) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2006.06.011 · Cited by 136 · see citing works
Guzmán-Villanueva, L. T., Tovar‐Ramírez, D., Gisbert, E., Cordero, H., Guardiola, F. A., Cuesta, A., Meseguer, J., Ascencio‐Valle, F., & Esteban, M. Á. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.04.024 · Cited by 133 · see citing works
Fc Receptors for Immunoglobulins and Their Appearance during Vertebrate Evolution
Akula, S., Mohammadamin, S., & Hellman, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096903 · Cited by 127 · see citing works
Rodríguez-Nunez, I., Chamorro, R., Novoa, B., & Figueras, A. J. (2009) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2009.02.007 · Cited by 126 · see citing works
Olivier, G., Eaton, C. A., & Campbell, N. (1986) · Veterinary Immunology and Immunopathology · doi:10.1016/0165-2427(86)90126-1 · Cited by 121 · see citing works
Skov, J., Kania, P. W., Holten-Andersen, L., Fouz, B., & Buchmann, K. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.04.009 · Cited by 116 · see citing works
Falcó, A., Frost, P., Miest, J. J., Pionnier, N. P., Irnazarow, I., & Hoole, D. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.02.028 · Cited by 115 · see citing works
Gopalakannan, A., & Arul, V. (2009) · Aquaculture Research · doi:10.1111/j.1365-2109.2009.02368.x · Cited by 106 · see citing works
Djordjevic, B., Škugor, S., Jørgensen, S. M., Øverland, M., Mydland, L. T., & Krasnov, A. (2008) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2008.10.012 · Cited by 102 · see citing works
Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo
Marakalala, M. J., Williams, D. L., Hoving, J. C., Engstad, R. E., Netea, M. G., & Brown, G. D. (2013) · Microbes and Infection · doi:10.1016/j.micinf.2013.03.002 · Cited by 87 · see citing works
Bagni, M., Archetti, L., Amadori, M., & Marino, G. (2000) · Journal of Veterinary Medicine Series B · doi:10.1046/j.1439-0450.2000.00412.x · Cited by 83 · see citing works
Chang, C.-S., Huang, S., Chen, S., & Chen, S.-N. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.04.004 · Cited by 82 · see citing works
Schmitt, P., Wacyk, J. M., Lange, B. M., Rojas, V., Guzmán, F., Dixon, B., & Mercado, L. A. (2015) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2015.03.007 · Cited by 76 · see citing works
Leentjens, J., Quintin, J., Gerretsen, J., Kox, M., Pickkers, P., & Netea, M. G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108794 · Cited by 76 · see citing works
Kawakami, H., Shinohara, N., & Sakai, M. (1998) · Fish Pathology · doi:10.3147/jsfp.33.287 · Cited by 75 · see citing works
Zhang, Z., Swain, T., Bøgwald, J., Dalmo, R. A., & Kumari, J. (2009) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2009.02.014 · Cited by 72 · see citing works
Przybylska, D. A., Schmidt, J. G., Jiménez, N. I. V., Steinhagen, D., & Nielsen, M. E. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.05.014 · Cited by 72 · see citing works
A Review of the Immunological Mechanisms Following Mucosal Vaccination of Finfish
Munang’andu, H. M., Mutoloki, S., & Evensen, Ø. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00427 · Cited by 70 · see citing works
Pietretti, D., Jiménez, N. I. V., Hoole, D., & Wiegertjes, G. F. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.06.022 · Cited by 67 · see citing works
Self-citationKühlwein, H., Emery, M., Rawling, M. D., Harper, G. M., Merrifield, D. L., & Davies, S. J. (2013) · Journal of Applied Microbiology · doi:10.1111/jam.12313 · Cited by 66 · see citing works
Falcó, A., Miest, J. J., Pionnier, N. P., Pietretti, D., Forlenza, M., Wiegertjes, G. F., & Hoole, D. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2013.12.005 · Cited by 64 · see citing works
Self-citationPionnier, N. P., Falcó, A., Miest, J. J., Frost, P., Irnazarow, I., Shrive, A. K., & Hoole, D. (2013) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.12.017 · Cited by 64 · see citing works
Rag1−/− Mutant Zebrafish Demonstrate Specific Protection following Bacterial Re-Exposure
Hohn, C., & Petrie-Hanson, L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044451 · Cited by 57 · see citing works
Fredriksen, B. N., Sævareid, K. L., McAuley, L., Lane, M. E., Bøgwald, J., & Dalmo, R. A. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.08.087 · Cited by 56 · see citing works
Fink, I. R., Benard, E. L., Hermsen, T., Meijer, A. H., Forlenza, M., & Wiegertjes, G. F. (2014) · Molecular Immunology · doi:10.1016/j.molimm.2014.09.010 · Cited by 56 · see citing works
Self-citationBrogden, G., von Köckritz‐Blickwede, M., Adamek, M., Reuner, F., Jung‐Schroers, V., Naim, H. Y., & Steinhagen, D. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.08.009 · Cited by 56 · see citing works
Brogden, G., Krimmling, T., Adamek, M., Naim, H. Y., Steinhagen, D., & von Köckritz‐Blickwede, M. (2014) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2014.01.003 · Cited by 52 · see citing works
Immune modulation by non-digestible and non-absorbable beta-1,3/1,6-glucan
Raa, J. (2015) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v26.27824 · Cited by 51 · see citing works
BCG vaccine confers adaptive immunity against Mycobacterium sp. infection in fish
Kato, G., Kondo, H., Aoki, T., & Hırono, I. (2009) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2009.08.013 · Cited by 51 · see citing works
Benard, E. L., Roobol, S. J., Spaink, H. P., & Meijer, A. H. (2014) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2014.07.022 · Cited by 51 · see citing works
Covello, J. M., Friend, S. E., Purcell, S. L., Burka, J. F., Markham, R. J. F., Donkin, A. W., Groman, D. B., & Fast, M. D. (2012) · Aquaculture · doi:10.1016/j.aquaculture.2012.08.051 · Cited by 49 · see citing works
Kato, G., Kondo, H., Aoki, T., & Hırono, I. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.05.002 · Cited by 48 · see citing works
Jung‐Schroers, V., Adamek, M., Jung, A., Harris, S., Dóza, Ö.-S., Baumer, A., & Steinhagen, D. (2015) · Aquaculture Nutrition · doi:10.1111/anu.12320 · Cited by 48 · see citing works
Pionnier, N. P., Falcó, A., Miest, J. J., Shrive, A. K., & Hoole, D. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.05.008 · Cited by 45 · see citing works
Miest, J. J., Falcó, A., Pionnier, N. P., Frost, P., Irnazarow, I., Williams, G. T., & Hoole, D. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.07.014 · Cited by 43 · see citing works
Evolution of the C-Type Lectin-Like Receptor Genes of the DECTIN-1 Cluster in the NK Gene Complex
Sattler, S., Ghadially, H., & Hofer, E. (2012) · The Scientific World JOURNAL · doi:10.1100/2012/931386 · Cited by 40 · see citing works
Lauridsen, J. H., & Buchmann, K. (2010) · Acta Ichthyologica Et Piscatoria · doi:10.3750/aip2010.40.1.08 · Cited by 39 · see citing works
Samuel, M., LAM, T. J., & Sin, Y. M. (1996) · Fish & Shellfish Immunology · doi:10.1006/fsim.1996.0042 · Cited by 39 · see citing works
Kato, G., Kato, K., Saito, K., Pe, Y., Kondo, H., Aoki, T., & Hırono, I. (2010) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2010.11.002 · Cited by 30 · see citing works
Immunomodulatory effect of prolactin on Atlantic salmon (Salmo salar) macrophage function
Marco Paredes, H., Gonzalez, K., Figueroa, J. E., & Montiel‐Eulefi, E. (2013) · Fish Physiology and Biochemistry · doi:10.1007/s10695-013-9777-7 · Cited by 28 · see citing works
Kudrenko, B., Snape, N., & Barnes, A. C. (2009) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2009.01.009 · Cited by 26 · see citing works
Hino, S., Kito, A., Yokoshima, R., Sugino, R., Oshima, K., Morita, T., Okajima, T., Nadano, D., Uchida, K., & Matsuda, T. (2012) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2012.04.009 · Cited by 25 · see citing works
CR3 complement receptor: Cloning and characterization in rainbow trout
Mikrou, A., Marioli, D. J., Papanastasiou, A. D., & Zarkadis, I. K. (2008) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2008.10.005 · Cited by 24 · see citing works
Uptake of yeast cells in the Atlantic salmon (Salmo salar L.) intestine
Løkka, G., Falk, K., Austbø, L., & Koppang, E. O. (2014) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2014.07.005 · Cited by 23 · see citing works
Guselle, N. J., Speare, D. J., Markham, R. J. F., & Patelakis, S. J. J. (2009) · North American Journal of Aquaculture · doi:10.1577/a09-017.1 · Cited by 23 · see citing works
Dalmo, R. A., Ingebrigtsen, K., Horsberg, T. E., & Seljelid, R. (1994) · Journal of Fish Diseases · doi:10.1111/j.1365-2761.1994.tb00256.x · Cited by 20 · see citing works
Detection of complement receptors on head kidney phagocytes of the common carp Cyprinus carpio
Nakao, M., Fujiki, K., Kondo, M., & Yano, T. (2003) · Fisheries Science · doi:10.1046/j.1444-2906.2003.00709.x · Cited by 19 · see citing works
Киселева, М. И., Balabanova, L., Elyakova, L. A., Rasskazov, V. A., & Николаевна, З. Т. (2013) · Journal of Fish Diseases · doi:10.1111/jfd.12043 · Cited by 12 · see citing works
Time and concentration dependency of MacroGard® induced apoptosis
Miest, J. J., & Hoole, D. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.11.009 · Cited by 9 · see citing works
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1 of the 92 references couldn’t be matched to a known paper.
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Sorted by citations
In Vitro Experimental Model of Trained Innate Immunity in Human Primary Monocytes
Bekkering, S., Blok, B. A., Joosten, L. A. B., Riksen, N. P., van Crevel, R., & Netea, M. G. (2016) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00349-16 · Cited by 346 · see citing works
Epigenetics and Trained Immunity
van der Heijden, C. D. C. C., Noz, M. P., Joosten, L. A. B., Netea, M. G., Riksen, N. P., & Keating, S. T. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7310 · Cited by 284 · see citing works
Exploring fish microbial communities to mitigate emerging diseases in aquaculture
de Bruijn, I., Liu, Y., Wiegertjes, G. F., & Raaijmakers, J. M. (2017) · FEMS Microbiology Ecology · doi:10.1093/femsec/fix161 · Cited by 269 · see citing works
Self-citationFeed, Microbiota, and Gut Immunity: Using the Zebrafish Model to Understand Fish Health
Nadal, A. L., Ikeda‐Ohtsubo, W., Sipkema, D., Peggs, D., McGurk, C., Forlenza, M., Wiegertjes, G. F., & Brugman, S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00114 · Cited by 252 · see citing works
Self-citationAdvances in Aquaculture Vaccines Against Fish Pathogens: Global Status and Current Trends
Dadar, M., Dhama, K., Vakharia, V. N., Hoseinifar, S. H., Karthik, K., Tiwari, R., Khandia, R., Munjal, A. K., Salgado-Miranda, C., & Joshi, S. K. (2016) · Reviews in Fisheries Science & Aquaculture · doi:10.1080/23308249.2016.1261277 · Cited by 246 · see citing works
Immunomodulatory Effect and Biological Significance of β-Glucans
Zhong, X., Wang, G., Li, F., Fang, S., Zhou, S., Ishiwata, A., Tonevitsky, A., Shkurnikov, M. Y., Cai, H., & Ding, F. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15061615 · Cited by 186 · see citing works
Oral vaccination of fish: Lessons from humans and veterinary species
Embregts, C. W. E., & Forlenza, M. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.03.024 · Cited by 178 · see citing works
Development of Fish Immunity and the Role of β-Glucan in Immune Responses
Rodrigues, M. V., Zanuzzo, F. S., Koch, J. F. A., de Oliveira, C. A. F., Šíma, P., & Větvička, V. (2020) · Molecules · doi:10.3390/molecules25225378 · Cited by 125 · see citing works
Dawood, M. A. O., Metwally, A. E.-S., El‐Sharawy, M. E., Atta, A. M., Elbialy, Z. I., Abdel‐Latif, H. M. R., & Paray, B. A. (2020) · Aquaculture · doi:10.1016/j.aquaculture.2020.735205 · Cited by 117 · see citing works
Douxfils, J., Fierro-Castro, C., Mandiki, S. N. M., Emile, W., Tort, L., & Kestemont, P. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.02.027 · Cited by 94 · see citing works
Carbohydrate utilisation by tilapia: a meta‐analytical approach
Maas, R. M., Verdegem, M. C. J., Wiegertjes, G. F., & Schrama, J. W. (2020) · Reviews in Aquaculture · doi:10.1111/raq.12413 · Cited by 93 · see citing works
Self-citationStudies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway
Petit, J., Bailey, E. C., Wheeler, R. T., de Oliveira, C. A. F., Forlenza, M., & Wiegertjes, G. F. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00280 · Cited by 90 · see citing works
Self-citationEvidence of Trained Immunity in a Fish: Conserved Features in Carp Macrophages
Petit, J., Embregts, C. W. E., Forlenza, M., & Wiegertjes, G. F. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1900137 · Cited by 85 · see citing works
Self-citationCarballo, C., Pinto, P. I. S., Mateus, A. P., Berbel, C., Guerreiro, C. C., Martínez-Blanch, J. F., Codoñer, F. M., Mantecón, L., Power, D. M., & Manchado, M. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.05.044 · Cited by 82 · see citing works
Dawood, M. A. O., Abdo, S. E., Gewaily, M. S., Moustafa, E. M., SaadAllah, M. S., El‐Kader, M. F. A., Hamouda, A. H., Omar, A. A. E.-D., & Wakeel, R. A. A. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.01.035 · Cited by 80 · see citing works
Trained Innate Immunity of Fish Is a Viable Approach in Larval Aquaculture
Zhang, Z., Chi, H., & Dalmo, R. A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.00042 · Cited by 79 · see citing works
Systemic and Mucosal B and T Cell Responses Upon Mucosal Vaccination of Teleost Fish
Muñoz-Atienza, E., Díaz‐Rosales, P., & Tafalla, C. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2020.622377 · Cited by 79 · see citing works
Carballo, C., Chronopoulou, E. G., Letsiou, S., Maya, C., Labrou, N. E., Infante, C., Power, D. M., & Manchado, M. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.07.052 · Cited by 73 · see citing works
Yeast β-Glucans as Fish Immunomodulators: A Review
Machuca, C., Méndez‐Martínez, Y., Reyes‐Becerril, M., & Angulo, C. (2022) · Animals · doi:10.3390/ani12162154 · Cited by 72 · see citing works
Gou, C., Wang, J., Wang, Y., Dong, W., Shan, X., Lou, Y., & Gao, Y. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.11.027 · Cited by 69 · see citing works
β-Glucan: Mode of Action and Its Uses in Fish Immunomodulation
Hadiuzzaman, M., Moniruzzaman, M., Shahjahan, M., Bai, S. C., Min, T., & Hossain, Z. (2022) · Frontiers in Marine Science · doi:10.3389/fmars.2022.905986 · Cited by 68 · see citing works
Dawood, M. A. O., El‐Kader, M. F. A., Moustafa, E. M., Gewaily, M. S., & Abdo, S. E. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-07775-8 · Cited by 67 · see citing works
Microalgae with immunomodulatory effects on fish
Bahi, A., Ramos‐Vega, A., Angulo, C., Monreal‐Escalante, E., & Guardiola, F. A. (2023) · Reviews in Aquaculture · doi:10.1111/raq.12792 · Cited by 65 · see citing works
Innate Immunomodulation in Food Animals: Evidence for Trained Immunity?
Byrne, K. A., Loving, C. L., & McGill, J. L. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01099 · Cited by 64 · see citing works
Koch, J. F. A., de Oliveira, C. A. F., & Zanuzzo, F. S. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.02.014 · Cited by 63 · see citing works
Beta-glucan enhances the response to SVCV infection in zebrafish
Medina-Gali, R. M., Ortega-Villaizán, M. D. M., Mercado, L. A., Novoa, B., Coll, J. M., & Pérez, L. (2018) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2018.02.019 · Cited by 63 · see citing works
Innate Immune Responses in Fish: Antigen Presenting Cells and Professional Phagocytes
Kordon, A. O., Karsi, A., & Pinchuk, L. M. (2018) · Turkish Journal of Fisheries and Aquatic Sciences · doi:10.4194/1303-2712-v18_9_11 · Cited by 63 · see citing works
Hansen, J. Ø., Lagos, L. X., Peng, L., Reveco, F. E., Lange, B. M., Hansen, L. D., Schiavone, M., Mydland, L. T., Arntzen, M. Ø., Mercado, L. A., et al. (2020) · Aquaculture · doi:10.1016/j.aquaculture.2020.735707 · Cited by 60 · see citing works
Gupta, A., Gupta, S. K., Priyam, M., Siddik, M. A. B., Kumar, N., Mishra, P. K., Gupta, S. K., Sarkar, B., Sharma, T. R., & Pattanayak, A. (2021) · Reviews in Aquaculture · doi:10.1111/raq.12581 · Cited by 55 · see citing works
Mokhbatly, A.-A. A., Assar, D. H., Ghazy, E., Elbialy, Z. I., Rizk, S. A., Omar, A. A. E.-D., Gaafar, A. Y., & Dawood, M. A. O. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-09333-8 · Cited by 54 · see citing works
Epidermal Club Cells in Fishes: A Case for Ecoimmunological Analysis
Pandey, S., Stockwell, C. A., Snider, M. R., & Wisenden, B. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031440 · Cited by 53 · see citing works
Immunostimulation and trained immunity in marine fish larvae
Rojo-Cebreros, A. H., Ibarra‐Castro, L., & Martínez-Brown, J. M. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.05.044 · Cited by 52 · see citing works
Kwon, K., Lamb, A., Fox, D., & Jegathese, S. J. P. (2019) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2019.01.038 · Cited by 53 · see citing works
Dawood, M. A. O., Moustafa, E. M., Elbialy, Z. I., Farrag, F. A., Lolo, E. E. E., Abdel-Daim, H. A., Abdel‐Daim, M. M., & Doan, H. V. (2020) · Research in Veterinary Science · doi:10.1016/j.rvsc.2020.03.019 · Cited by 52 · see citing works
Yamamoto, F. Y., Yin, F., Rossi, W., Hume, M., & Gatlin, D. M. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.04.003 · Cited by 51 · see citing works
β-Glucans from Yeast—Immunomodulators from Novel Waste Resources
Thomas, S., Rezoagli, E., Abidin, I. Z., Major, I., Murray, P., & Murphy, E. J. (2022) · Applied Sciences · doi:10.3390/app12105208 · Cited by 51 · see citing works
Gewaily, M. S., Shukry, M., El‐Kader, M. F. A., Alkafafy, M., Farrag, F. A., Moustafa, E. M., Doan, H. V., Abdelghany, M. F., Abdelhamid, A. F., Eltanahy, A., et al. (2021) · Frontiers in Marine Science · doi:10.3389/fmars.2021.621558 · Cited by 51 · see citing works
Petit, J., de Bruijn, I., Goldman, M. R. G., van den Brink, E., Pellikaan, W. F., Forlenza, M., & Wiegertjes, G. F. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2021.761820 · Cited by 47 · see citing works
Self-citationVaccination of carp against SVCV with an oral DNA vaccine or an insect cells-based subunit vaccine
Embregts, C. W. E., Rigaudeau, D., Tacchi, L., Pijlman, G. P., Kampers, L. F. C., Veselý, T., Pokorová, D., Boudinot, P., Wiegertjes, G. F., & Forlenza, M. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.03.028 · Cited by 50 · see citing works
Self-citationIkewaki, N., Iwasaki, M., Kurosawa, G., Rao, K. S. J., Lakey‐Beitia, J., Preethy, S., & Abraham, S. J. (2021) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2021.1880210 · Cited by 48 · see citing works
Edwardsiella ictaluri : A systemic review and future perspectives on disease management
Machimbirike, V. I., Crumlish, M., Dong, H. T., Santander, J., Khunrae, P., & Rattanarojpong, T. (2022) · Reviews in Aquaculture · doi:10.1111/raq.12665 · Cited by 47 · see citing works
Pérez-Pascual, D., Pérez‐Cobas, A. E., Rigaudeau, D., Rochat, T., Bernardet, J., Cassy, S., Marchand, Y., Duchaud, É., & Ghigo, J. (2021) · Animal Microbiome · doi:10.1186/s42523-021-00107-2 · Cited by 46 · see citing works
Stress and immune system in fish
Urbinati, E. C., Zanuzzo, F. S., & Biller, J. D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815872-2.00005-1 · Cited by 45 · see citing works
Zhou, J., Lv, J., Carlson, C., Liu, H., Wang, H., Xu, T., Wu, F., Song, C., Wang, X., Wang, T., et al. (2021) · Emerging Microbes & Infections · doi:10.1080/22221751.2021.1899771 · Cited by 43 · see citing works
García-Valtanen, P., Martínez‐López, A., López‐Muñoz, A., Belló-Pérez, M., Medina-Gali, R. M., Ortega-Villaizán, M. D. M., Varela, M., Figueras, A. J., Mulero, V., Novoa, B., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00121 · Cited by 44 · see citing works
Cho, S. Y., Kim, H. J., Lan, N. T., Han, H., Lee, D.-C., Hwang, J. Y., Kwon, M., Kang, B. K., Han, S. Y., Moon, H., et al. (2017) · Veterinary Microbiology · doi:10.1016/j.vetmic.2017.04.022 · Cited by 43 · see citing works
Álvarez-Rodríguez, M., Pereiro, P., Reyes‐López, F. E., Tort, L., Figueras, A. J., & Novoa, B. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01575 · Cited by 40 · see citing works
Yamamoto, F. Y., Sutili, F. J., Hume, M. E., & Gatlin, D. M. (2018) · Journal of Fish Diseases · doi:10.1111/jfd.12871 · Cited by 41 · see citing works
β-Glucan as Trained Immunity-Based Adjuvants for Rabies Vaccines in Dogs
Paris, S., Chapat, L., Martin-Cagnon, N., Durand, P.-Y., Piney, L., Cariou, C., Bergamo, P., Bonnet‐Garin, J., Poulet, H., Freyburger, L., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.564497 · Cited by 41 · see citing works
β-Glucan-Induced Trained Immunity in Dogs
Paris, S., Chapat, L., Pasin, M., Lambiel, M., Sharrock, T. E., Shukla, R., Sigoillot-Claude, C., Bonnet‐Garin, J., Poulet, H., Freyburger, L., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.566893 · Cited by 40 · see citing works
Plant‐based feed additives in Cyprinus carpio aquaculture
Kuebutornye, F. K. A., Roy, K., Folorunso, E. A., & Mráz, J. (2023) · Reviews in Aquaculture · doi:10.1111/raq.12840 · Cited by 39 · see citing works
Reyes‐Becerril, M., Guluarte, C., Ceballos‐Francisco, D., Angulo, C., & Esteban, M. Á. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.03.027 · Cited by 39 · see citing works
Arneth, B. M. (2021) · Immunologic Research · doi:10.1007/s12026-021-09170-y · Cited by 38 · see citing works
Immunological memory in teleost fish
Stosik, M. P., Tokarz–Deptuła, B., & Deptuła, W. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.05.022 · Cited by 39 · see citing works
Sherif, A. H., & Mahfouz, M. E. (2019) · Aquaculture · doi:10.1016/j.aquaculture.2019.05.016 · Cited by 37 · see citing works
Dawood, M. A. O., Abdel-Razik, N. I., Gewaily, M. S., Sewilam, H., Paray, B. A., Soliman, A. A., Abdelhiee, E. Y., Aboubakr, M., Doan, H. V., Elsabagh, M., et al. (2020) · Aquaculture Reports · doi:10.1016/j.aqrep.2020.100549 · Cited by 38 · see citing works
Moreira, R., Romero, A., Rey-Campos, M., Pereiro, P., Rosani, U., Novoa, B., & Figueras, A. J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.606102 · Cited by 38 · see citing works
Mu, D., Yang, J., Jiang, Y. J., Wang, Z., Chen, W., Huang, J., Zhang, Y., Liu, Q., & Yang, D. (2022) · The Journal of Immunology · doi:10.4049/jimmunol.2200225 · Cited by 38 · see citing works
Zhang, M., Chen, X., Xue, M., Jiang, N., Li, Y., Fan, Y., Zhang, P., Liu, N., Xiao, Z., Zhang, Q., et al. (2023) · Animals · doi:10.3390/ani13071183 · Cited by 37 · see citing works
Gewaily, M. S., Abdo, S. E., Moustafa, E. M., El‐Kader, M. F. A., El-Razek, I. M. A., El-sharnouby, M. E., Alkafafy, M., Raza, S. H. A., Basuini, M. F. E., Doan, H. V., et al. (2021) · Animals · doi:10.3390/ani11061790 · Cited by 37 · see citing works
Dang, Y., Sun, Y., Zhou, Y., Men, X., Wang, B., Li, B., & Ren, Y. (2022) · Aquaculture · doi:10.1016/j.aquaculture.2022.738668 · Cited by 37 · see citing works
Sîrbu, E., Dima, F. M., Tenciu, M., Crețu, M., COADĂ, M. T., Țoțoiu, A., Cristea, V., & Patriche, N. (2022) · Fishes · doi:10.3390/fishes7050273 · Cited by 36 · see citing works
van Splunter, M. E., van Osch, T. L. J., Brugman, S., Savelkoul, H. F. J., Joosten, L. A. B., Netea, M. G., & van Neerven, R. J. J. (2018) · Nutrients · doi:10.3390/nu10101378 · Cited by 36 · see citing works
Reis, B., Gonçalves, A. T., Santos, P., Sardinha, M., Conceição, L. E. C., Serradeiro, R., Pérez‐Sánchez, J., Calduch-Giner, J. À., Schmid‐Staiger, U., Frick, K., et al. (2021) · Marine Drugs · doi:10.3390/md19120653 · Cited by 36 · see citing works
de Souza, F. P., de Lima, E. C. S., Pandolfi, V. C. F., Leite, N. G., Murari, P. J. F., Leal, C. N. S., Mainardi, R. M., Suphoronski, S. A., Favero, L. M., Koch, J. F. A., et al. (2020) · Aquaculture Reports · doi:10.1016/j.aqrep.2020.100369 · Cited by 35 · see citing works
Jung‐Schroers, V., Adamek, M., Harris, S., Syakuri, H., Jung, A., Irnazarow, I., & Steinhagen, D. (2018) · Journal of Fish Diseases · doi:10.1111/jfd.12799 · Cited by 34 · see citing works
Functional diets in fish health management
Waagbø, R., & Remø, S. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-813359-0.00007-5 · Cited by 34 · see citing works
Pichia pastoris yeast as a vehicle for oral vaccination of larval and adult teleosts
Embregts, C. W. E., Reyes‐López, F. E., Pall, A., Stratmann, A., Tort, L., Lorenzen, N., Engell-Sørensen, K., Wiegertjes, G. F., Forlenza, M., Sunyer, J. O., et al. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.07.033 · Cited by 34 · see citing works
Self-citationPogue, R. E., Murphy, E. J., Fehrenbach, G. W., Rezoagli, E., & Rowan, N. J. (2021) · Current Opinion in Environmental Science & Health · doi:10.1016/j.coesh.2021.100248 · Cited by 33 · see citing works
Krishnan, R., Jang, Y., & Oh, M. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.01.005 · Cited by 34 · see citing works
Mahapatra, S., Ganguly, B., Pani, S., Saha, A., & Samanta, M. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.126541 · Cited by 32 · see citing works
El-Bouhy, Z. M., Reda, R. M., Mahboub, H. H. H., & Gomaa, F. N. (2021) · Aquaculture Research · doi:10.1111/are.15227 · Cited by 31 · see citing works
β-Glucan successfully stimulated the immune system in different jawed vertebrate species
de Oliveira, C. A. F., Větvička, V., & Zanuzzo, F. S. (2018) · Comparative Immunology Microbiology and Infectious Diseases · doi:10.1016/j.cimid.2018.11.006 · Cited by 30 · see citing works
Yousefi, S., Shokri, M. M., Noveirian, H. A., & Hoseinifar, S. H. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.08.007 · Cited by 30 · see citing works
Doan, H. V., Sumon, M. A. A., Tran, H. Q., Le, C. X., Mohammady, E. Y., El‐Haroun, E., Hoseinifar, S. H., Ringø, E., Stejskal, V., & Dawood, M. A. O. (2024) · Reviews in Aquaculture · doi:10.1111/raq.12944 · Cited by 27 · see citing works
Liu, Z., Wu, J., Ma, Y., Hao, L., Liang, Z., Ma, J., Ke, H., Li, Y., & Cao, J. (2020) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2020.01.034 · Cited by 27 · see citing works
Menanteau‐Ledouble, S., Skov, J., Lukassen, M. B., Rolle-Kampczyk, U. E., Haange, S., Dalsgaard, I., von Bergen�, M., & Nielsen, J. L. (2022) · Animal Microbiome · doi:10.1186/s42523-022-00209-5 · Cited by 26 · see citing works
Romano, N. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821339-1.00003-9 · Cited by 26 · see citing works
Ma, Y., Liu, Z., Hao, L., Wu, J., Qin, B., Liang, Z., Ma, J., Ke, H., Yang, H.-W., Li, Y., et al. (2020) · Research in Veterinary Science · doi:10.1016/j.rvsc.2020.03.013 · Cited by 25 · see citing works
Βeta-glucan stimulation induces trained immunity markers in common carp, Cyprinus carpio
Waikhom, D., Jeena, K., Krishnan, R., Varghese, T., Kurcheti, P. P., & Valappil, R. K. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.10.069 · Cited by 24 · see citing works
Deng, S., Choto, P., Gwekwe, B., Li, Y., Akida, J. S., Pang, Z., Huang, Y., Dang, Y., Wang, S., Chen, M., et al. (2019) · Aquaculture Reports · doi:10.1016/j.aqrep.2019.100234 · Cited by 23 · see citing works
Rawling, M. D., Leclercq, E., Foey, A., Castex, M., & Merrifield, D. L. (2021) · PLoS ONE · doi:10.1371/journal.pone.0245021 · Cited by 23 · see citing works
Porter, D., Peggs, D., McGurk, C., & Martín, S. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.05.055 · Cited by 23 · see citing works
Zhao, F., Huo, X., Wang, P., Liu, Q., Yang, C., & Su, J. (2023) · Microorganisms · doi:10.3390/microorganisms11102529 · Cited by 23 · see citing works
Medina-Gali, R. M., Belló-Pérez, M., Martínez‐López, A., Falcó, A., Ortega-Villaizán, M. D. M., Encinar, J. A., Novoa, B., Coll, J. M., & Pérez, L. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.08.056 · Cited by 23 · see citing works
Progress and perspective of trained immunity in teleost fish
You, X., Yang, J., Wang, Z., Wang, Q., Liu, Q., Zhang, Y., Wiegertjes, G. F., & Yang, D. (2023) · Reviews in Aquaculture · doi:10.1111/raq.12863 · Cited by 23 · see citing works
Self-citationTissue-resident trained immunity in hepatocytes protects against septic liver injury in zebrafish
Wang, Z., Liu, Y., Hu, J., You, X., Yang, J., Zhang, Y., Liu, Q., & Yang, D. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114324 · Cited by 23 · see citing works
Nutritional supplements and fish health
Gatlin, D. M., & Yamamoto, F. Y. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819587-1.00004-5 · Cited by 22 · see citing works
Juste, R. A., Ferreras‐Colino, E., de la Fuente, J., Domínguez, M., Risalde, M. Á., Domı́nguez, L., Cabezas‐Cruz, A., & Gortázar, C. (2022) · Immunology · doi:10.1111/imm.13529 · Cited by 21 · see citing works
Dietary β-glucan enhances the contents of complement component 3 and factor B in eggs of zebrafish
Jiang, C., Wang, P., Li, M., Liu, S., & Zhang, S. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.06.022 · Cited by 20 · see citing works
Barsøe, S., Skovgaard, K., Sepúlveda, D., Stratmann, A., Vendramin, N., & Lorenzen, N. (2021) · Pathogens · doi:10.3390/pathogens10111477 · Cited by 19 · see citing works
Trained Immunity Provides Long-Term Protection against Bacterial Infections in Channel Catfish
Petrie-Hanson, L., & Peterman, A. E. (. (2022) · Pathogens · doi:10.3390/pathogens11101140 · Cited by 19 · see citing works
Han, B., Zhang, X., Chang, E., Wan, W., Xu, J., Zhao, C., & Miao, S. (2021) · Aquaculture Nutrition · doi:10.1111/anu.13346 · Cited by 18 · see citing works
Waikhom, D., Jeena, K., Suresh, S. N., Bedekar, M. K., Varghese, T., Kurcheti, P. P., & Valappil, R. K. (2024) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2024.105188 · Cited by 18 · see citing works
Trans-generational enhancement of C-type lysozyme level in eggs of zebrafish by dietary β-glucan
Wang, P., Jiang, C., Liu, S., Cui, P., Zhang, Y., & Zhang, S. (2017) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2017.04.006 · Cited by 17 · see citing works
Porter, D., Peggs, D., McGurk, C., & Martín, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1023235 · Cited by 16 · see citing works
Abdel-Mawla, M. S., Magouz, F. I., Khalafalla, M. M., Amer, A. A., Soliman, A. A., Zaineldin, A. I., Gewaily, M. S., & Dawood, M. A. O. (2023) · Journal of Applied Phycology · doi:10.1007/s10811-023-02973-6 · Cited by 15 · see citing works
Song, X., Lei, T., Cui, N., Jin, X., Huang, Y. K., Shi, Y., & Zhao, Z. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.110035 · Cited by 15 · see citing works
Ulvestad, J. S., Kumari, J., Seternes, T., Chi, H., & Dalmo, R. A. (2018) · Journal of Fish Diseases · doi:10.1111/jfd.12806 · Cited by 15 · see citing works
Osteichthyes: Immune Systems of Teleosts (Actinopterygii)
Nakanishi, T., Hikima, J.-I., & Yada, T. (2018) · Springer eBooks · doi:10.1007/978-3-319-76768-0_19 · Cited by 14 · see citing works
- Authors
- Petit, J., & Wiegertjes, G. F.
- Affiliations
- Wageningen University & Research (NL)
- Corresponding author
- Wiegertjes, Geert F.
- Venue
- Developmental & Comparative Immunology
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 64
- Pages
- 93-102
- ISSN
- 0145-305X (ISSN-L)
- OpenAlex
- W2288992930
- Cited by
- 196
- References
- 92
- Citations by year
- 2026: 18 · 2025: 15 · 2024: 28 · 2023: 17 · 2022: 22 · 2021: 27 · 2020: 24 · 2019: 12 · 2018: 18 · 2017: 11 · 2016: 4
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Developmental & Comparative Immunology (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Socio-Environmental Systems Modeling (acceptedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, cc-by)
- Funders
- Netherlands Organisation for Scientific Research
- São Paulo Research Foundation, Brazil
- NWO-FAPESP Programme (729.004.002)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Aquaculture disease management and microbiota
- Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- β-glucan, trained immunity, teleosts, innate immunity, macrophages, natural killer cells, immunomodulation, gut microbiota, receptor recognition, fish farming
- MeSH terms
- Animals, Fishes, Immune System, Immunization, Immunologic Memory, Intestines, Killer Cells, Natural, Macrophages, Mammals, Signal Transduction, Immunity, Mucosal, beta-Glucans, Receptors, Pattern Recognition, Microbiota
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