The Hippo Signaling Pathway in Development and Disease

Zheng, Yonggang, Pan, Duojia·2019·Developmental Cell

Cites (262)

Items 201–262 of 262

  1. A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney disease
    Jing Cai, Xuewen Song, Wei Wang, Terry J. Watnick, York Pei, Feng Qian, Duojia Pan · 2018 · Genes & Development
  2. Integrin signalling regulates YAP and TAZ to control skin homeostasis
    Ahmed Elbediwy, Zoé I. Vincent‐Mistiaen, Bradley Spencer‐Dene, Richard K. Stone, Stefan Boeing, Stefanie K. Wculek, Julia B. Cordero, Ee Hong Tan, Rachel A. Ridgway, Val Brunton et al. · 2016 · Journal of Cell Science
  3. YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
    Chuwen Lin, Erica Yao, Kuan Zhang, Xuan Jiang, Stacey Croll, Katherine L. Thompson-Peer, Pao‐Tien Chuang · 2017 · eLife
  4. CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic Transformation
    Shuping Yang, Lin Zhang, Miao Liu, Rong Chong, Shi‐Jian Ding, Yuanhong Chen, Jixin Dong · 2013 · Cancer Research
  5. Altered Hippo signalling in polycystic kidney disease
    Hester Happé, Annemieke M. van der Wal, Wouter N. Leonhard, Steven J. Kunnen, Martijn H. Breuning, Emile de Heer, Dorien J.M. Peters · 2011 · The Journal of Pathology
  6. Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modules
    Chih‐Chao Yang, Hillary K. Graves, Iván M. Moya, Chunyao Tao, Fisun Hamaratoǧlu, Andrew B. Gladden, Georg A. Halder · 2015 · Proceedings of the National Academy of Sciences
  7. Hippo Pathway Gene Mutations in Malignant Mesothelioma: Revealed by RNA and Targeted Exon Sequencing
    Akihiko Miyanaga, Mari Masuda, Koji Tsuta, Kumiko Kawasaki, Yuka Nakamura, Tomohiro Sakuma, Hisao Asamura, Akihiko Gemma, Tesshi Yamada · 2015 · Journal of Thoracic Oncology
  8. Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded
    Ting Su, Michael Z. Ludwig, Jiajie Xu, Richard G. Fehon · 2017 · Developmental Cell
  9. Heterozygous Loss-of-Function Mutations in YAP1 Cause Both Isolated and Syndromic Optic Fissure Closure Defects
    Kathleen A. Williamson, Joe Rainger, James A. B. Floyd, Morad Ansari, Alison M. Meynert, Kishan Victoria Aldridge, Jacqueline K. Rainger, Carl A. Anderson, Anthony T. Moore, Matthew E. Hurles et al. · 2014 · The American Journal of Human Genetics
  10. Collagen synthesis disruption and downregulation of core elements of TGF-β, Hippo, and Wnt pathways in keratoconus corneas
    Michał Kabza, Justyna A. Karolak, Małgorzata Rydzanicz, Michał Wojciech Szcześniak, Dorota M. Nowak-Malczewska, Barbara Ginter-Matuszewska, Piotr Polakowski, Rafał Płoski, Jacek Paweł Szaflik, Marzena Gajęcka · 2017 · European Journal of Human Genetics
  11. Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus
    Raehee Park, Uk Yeol Moon, Jun Yong Park, Lucinda J. Hughes, Randy L. Johnson, Seo‐Hee Cho, Seonhee Kim · 2016 · Nature Communications
  12. Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex
    Zheng, Yonggang, Liu, Bo, Wang, Li, Lei, Huiyan, Pulgar Prieto, Katiuska Daniela, Pan, Duojia · 2017 · Cell Reports
  13. Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth
    Chiara V. Ragni, Nicolas Diguet, Jean‐François Le Garrec, Marta Novotová, Tatiana Pinho Resende, Sorin Pop, Nicolas Charon, Laurent Guillemot, Lisa Kitasato, Caroline Badouel et al. · 2017 · Nature Communications
  14. Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
    Michael C. Wehr, Maxine V. Holder, Ieva Gailite, Rebecca E. Saunders, Tobias M Maile, Elena Ciirdaeva, Rachael Instrell, Ming Jiang, Michael T. Howell, Moritz J. Rossner et al. · 2012 · Nature Cell Biology
  15. FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
    Suyuan Ji, Qingxu Liu, Shihao Zhang, Qinghua Chen, Cong Wang, Weiji Zhang, Xiao Chen, Yuxi Li, Cheng Nian, Jiaxin Li et al. · 2019 · Developmental Cell
  16. MST1 functions as a key modulator of neurodegeneration in a mouse model of ALS
    Jae Keun Lee, Jin Hee Shin, Sang Gil Hwang, Byoung Joo Gwag, Ann Carolyn McKee, Jung-Hee Lee, Neil W. Kowall, Hoon Ryu, Dae‐Sik Lim, Eui‐Ju Choi · 2013 · Proceedings of the National Academy of Sciences
  17. The Roles of NDR Protein Kinases in Hippo Signalling
    Alexander Hergovich · 2016 · Genes
  18. Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ
    Jing Yi, Li Lu, Kilangsungla Yanger, Wenqi Wang, Bo Hwa Sohn, Ben Z. Stanger, Min Zhang, James F. Martin, Jaffer A. Ajani, Junjie Chen et al. · 2016 · Hepatology
  19. Spectrin regulates Hippo signaling by modulating cortical actomyosin activity
    Hua Deng, Wei Wang, Jianzhong Yu, Yonggang Zheng, Yun Qing, Duojia Pan · 2015 · eLife
  20. Mechanical strain regulates the Hippo pathway in Drosophila
    Georgina Fletcher, María-del-Carmen Díaz-de-la-Loza, Nerea Borreguero-Muñoz, Maxine V. Holder, Mario Aguilar‐Aragon, Barry J. Thompson · 2018 · Development
  21. Drosophila Pez Acts in Hippo Signaling to Restrict Intestinal Stem Cell Proliferation
    Ingrid Poernbacher, Roland Baumgartner, Suresh Marada, Kevin A. Edwards, Hugo Stocker · 2012 · Current Biology
  22. The Cell Adhesion Molecule Echinoid Functions as a Tumor Suppressor and Upstream Regulator of the Hippo Signaling Pathway
    Tao Yue, Aiguo Tian, Jin Jiang · 2012 · Developmental Cell
  23. High-Molecular-Weight Hyaluronan Is a Hippo Pathway Ligand Directing Cell Density-Dependent Growth Inhibition via PAR1b
    Takuya Ooki, Naoko Murata‐Kamiya, Atsushi Takahashi‐Kanemitsu, Weida Wu, Masanori Hatakeyama · 2019 · Developmental Cell
  24. R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability
    Hsuan‐Yu Chen, Sung‐Liang Yu, Bing‐Ching Ho, Kang‐Yi Su, Yi‐Chiung Hsu, Chi-Sheng Chang, Yu-Cheng Li, Shi‐Yi Yang, Pin-Yen Hsu, Hao H. Ho et al. · 2015 · Journal of Clinical Oncology
  25. Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation
    Ataaillah Benhaddou, Céline Keime, Tao Ye, Aurore Morlon, Isabelle Michel, Bernard Jost, Gabrielle Mengus, Irwin Davidson · 2011 · Cell Death and Differentiation
  26. Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
    Lisheng Ni, Sheng Li, Jianzhong Yu, Jungki Min, Chad A. Brautigam, Diana R. Tomchick, Duojia Pan, Xuelian Luo · 2013 · Structure
  27. YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme
    Jennifer L. Cotton, Qi Li, Lifang Ma, Joo‐Seop Park, Jiayi Wang, Jianhong Ou, Lihua Julie Zhu, Yicktung Tony Ip, Randy L. Johnson, Junhao Mao · 2017 · Developmental Cell
  28. Biallelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney
    Rohit Mehra, Pankaj Vats, Marcin P. Cieslik, Xuhong Cao, Fengyun Su, Sudhanshu Kumar Shukla, Aaron M. Udager, Rui Wang, Jincheng Pan, Katayoon Kasaian et al. · 2016 · Cancer Discovery
  29. YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis
    K. Taniguchi, Toshiro Moroishi, P. de Jong, M. Krawczyk, B. M. Grebbin, Hui-Yan Luo, Rui-Hua Xu, N. Golob-Schwarzl, C. Schweiger, Ke-Peng Wang et al. · 2017 · Proceedings of the National Academy of Sciences of the United States of America
  30. Opposite Feedbacks in the Hippo Pathway for Growth Control and Neural Fate
    David Jukam, Baotong Xie, Jens Rister, David Terrell, Mark A. Charlton-Perkins, Daniela Pistillo, Brian A. Gebelein, Claude Desplan, Tiffany A. Cook · 2013 · Science
  31. The H ippo pathway in chemotherapeutic drug resistance
    Yulei Zhao, Xiaolong Yang · 2014 · International Journal of Cancer
  32. Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation
    Yoshitaka Sekido · 2011 · Pathology International
  33. Transcriptional integration of mitogenic and mechanical signals by Myc and YAP
    Ottavio Croci, Serena Fazio, Francesca Biagioni, Elisa Donato, Marieta Cagánová, Laura Curti, Mirko Doni, Silvia Sberna, Deborah Aldeghi, Chiara Biancotto et al. · 2017 · Genes & Development
  34. A Sveinsson’s chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ
    Michinori Kitagawa · 2007 · Biochemical and Biophysical Research Communications
  35. Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway
    Gao Liu, Fa‐Xing Yu, Young Chul Kim, Zhipeng Meng, Julián Naipauer, David J. Looney, Xiangguo Liu, Jorge Silvio Gutkind, Enrique A. Mesri, K-L Guan · 2014 · Oncogene
  36. Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation
    Fansen Meng, Ruyuan Zhou, Shiying Wu, Qian Zhang, Qiuheng Jin, Yao Zhou, Steven W. Plouffe, Shengduo Liu, Hai Song, Zongping Xia et al. · 2016 · Genes & Development
  37. The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth
    Fisun Hamaratoǧlu, Kathleen M. Gajewski, Leticia Sansores-García, Clayton M. Morrison, Chunyao Tao, Georg A. Halder · 2009 · Journal of Cell Science
  38. Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase Complex
    Hyangyee Oh, Matthew G. Slattery, Lijia Ma, Kevin P. White, Richard S. Mann, Kenneth D. Irvine · 2014 · Cell Reports
  39. Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation
    Helen McNeill, Antoine Reginensi · 2016 · Journal of the American Society of Nephrology
  40. The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6
    Yun Qing, Feng Yin, Wei Wang, Yonggang Zheng, Pengfei Guo, Frederick Schozer, Hua Deng, Duojia Pan · 2014 · eLife
  41. Hippo signaling in the kidney: the good and the bad
    Jenny Wong, Kristin A. Meliambro, Justina Ray, Kirk Nicholas Campbell · 2016 · American Journal of Physiology-Renal Physiology
  42. Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling
    Yunyun Jin, Jinjin Xu, Meng-Xin Yin, Yi Lu, Lianxin Hu, Peixue Li, Peng Zhang, Zengqiang Yuan, Margaret Su-chun Ho, Hongbin Ji et al. · 2013 · eLife
  43. Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase Warts
    Alina M. Vrabioiu, Gary Struhl · 2015 · Developmental Cell
  44. The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren's syndrome
    Tone Bull Enger, Arman Samad-Zadeh, Meghan P. Bouchie, Kathrine Skarstein, Hilde Kanli Galtung, Toshiyuki Mera, Janice L. Walker, A. Sue Menko, Xaralabos Varelas, Denise Louise Faustman et al. · 2013 · Laboratory Investigation
  45. Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease
    Liqun Wang, Jing Xia, Jonathan Li, Tracy L. Hagemann, Jeffrey R. Jones, Ernest Fraenkel, David A. Weitz, Su‐Chun Zhang, Albee Messing, Mel Β. Feany · 2018 · Nature Communications
  46. Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system
    Ieva Gailite, Birgit L. Aerne, Nicolas Tapon · 2015 · Proceedings of the National Academy of Sciences
  47. Scaling the Drosophila Wing: TOR-Dependent Target Gene Access by the Hippo Pathway Transducer Yorkie
    Joseph Parker, Gary Struhl · 2015 · PLoS Biology
  48. From vestigial to vestigial-like: the Drosophila gene that has taken wing
    Emilie Simon, Corinne Faucheux, Alain Zider, Nadine Thézé, Pierre Thiébaud · 2016 · Development Genes and Evolution
  49. Big roles for Fat cadherins
    Seth S. Blair, Helen McNeill · 2017 · Current Opinion in Cell Biology
  50. Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit
    Brandon Nicolay, Battuya Bayarmagnai, Abul Bashar Mir Md. Khademul Islam, Núria López-Bigas, Maxim V. Frolov · 2011 · Genes & Development
  51. WW and C2 domain–containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway
    Anke Hermann, Dirk Oliver Wennmann, Sascha Gromnitza, Maria Edeling, Veerle Van Marck, Marius Sudol, Liliana Schaefer, Kerstin Duning, Thomas Weide, Hermann Josef Pavenstädt et al. · 2017 · Hepatology
  52. Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K
    Yong Suk Cho, Jian Zhu, Shuangxi Li, Bing Wang, Yuhong Han, Jin Jiang · 2018 · Nature Communications
  53. The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland
    Aleksander D. Szymaniak, Rongjuan Mi, Shannon E. McCarthy, Adam C. Gower, Taylor L. Reynolds, Michaël Mingueneau, Maria A. Kukuruzinska, Xaralabos Varelas · 2017 · eLife
  54. The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish
    Jason Kuan Han Lai, Michelle M. Collins, Verónica Uribe, Vanesa Jiménez-Amilburu, Stefan Günther, Hans‐Martin Maischein, Didier Y. R. Stainier · 2018 · Development
  55. Making the Mouse Blastocyst
    Janet Rossant · 2016 · Current topics in developmental biology/Current Topics in Developmental Biology
  56. Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control
    Yavuz Kulaberoglu, Kui Lin, Maxine V. Holder, Zhongchao Gai, Marta Gómez-Ferrer, Belul Assefa Shifa, Merdiye Mavis, Lily Hoa, Ahmad A.D. Sharif, Celia Lujan et al. · 2017 · Nature Communications
  57. Fat-regulated adaptor protein Dlish binds the growth suppressor Expanded and controls its stability and ubiquitination
    Xing Wang, Yifei Zhang, Seth S. Blair · 2019 · Proceedings of the National Academy of Sciences
  58. Viral Small T Oncoproteins Transform Cells by Alleviating Hippo-Pathway-Mediated Inhibition of the YAP Proto-oncogene
    Thanh Nguyen, Xin Hong, Sam Tan, Qingfeng Chen, Lifang Chan, Marc L. Fivaz, Stephen Michael Cohen, Pieter Mathijs Voorhoeve · 2014 · Cell Reports
  59. Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass
    Nicholas M. George, Brian P. Boerner, Shakeel U.R. Mir, Zachary P. Guinn, Nora Sarvetnick · 2015 · Molecular Endocrinology
  60. Nerfin-1 represses transcriptional output of Hippo signaling in cell competition
    Pengfei Guo, Chang-Hyun Lee, Huiyan Lei, Yonggang Zheng, Katiuska Daniela Pulgar Prieto, Duojia Pan · 2019 · eLife
  61. Disruption of mechanical stress in extracellular matrix is related to Stanford type A aortic dissection through down-regulation of Yes-associated protein
    Wenjian Jiang, Wei-Hong Ren, Xujie Liu, Yan Liu, Fujian Wu, Li‐Zhong Sun, Feng Lan, Jie Du, Hongjia Zhang · 2016 · Aging
  62. Validating upstream regulators of Yorkie activity in Hippo signaling through scalloped-based genetic epistasis
    Jianzhong Yu, Duojia Pan · 2018 · Development