The Hippo Signaling Pathway in Development and Disease
Zheng, Yonggang, Pan, Duojia·2019·Developmental Cell
Cites (262)
Items 201–262 of 262
- A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney diseaseJing Cai, Xuewen Song, Wei Wang, Terry J. Watnick, York Pei, Feng Qian, Duojia Pan · 2018 · Genes & Development
- Integrin signalling regulates YAP and TAZ to control skin homeostasisAhmed Elbediwy, Zoé I. Vincent‐Mistiaen, Bradley Spencer‐Dene, Richard K. Stone, Stefan Boeing, Stefanie K. Wculek, Julia B. Cordero, Ee Hong Tan, Rachel A. Ridgway, Val Brunton et al. · 2016 · Journal of Cell Science
- YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesisChuwen Lin, Erica Yao, Kuan Zhang, Xuan Jiang, Stacey Croll, Katherine L. Thompson-Peer, Pao‐Tien Chuang · 2017 · eLife
- CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic TransformationShuping Yang, Lin Zhang, Miao Liu, Rong Chong, Shi‐Jian Ding, Yuanhong Chen, Jixin Dong · 2013 · Cancer Research
- Altered Hippo signalling in polycystic kidney diseaseHester Happé, Annemieke M. van der Wal, Wouter N. Leonhard, Steven J. Kunnen, Martijn H. Breuning, Emile de Heer, Dorien J.M. Peters · 2011 · The Journal of Pathology
- Differential regulation of the Hippo pathway by adherens junctions and apical–basal cell polarity modulesChih‐Chao Yang, Hillary K. Graves, Iván M. Moya, Chunyao Tao, Fisun Hamaratoǧlu, Andrew B. Gladden, Georg A. Halder · 2015 · Proceedings of the National Academy of Sciences
- Hippo Pathway Gene Mutations in Malignant Mesothelioma: Revealed by RNA and Targeted Exon SequencingAkihiko Miyanaga, Mari Masuda, Koji Tsuta, Kumiko Kawasaki, Yuka Nakamura, Tomohiro Sakuma, Hisao Asamura, Akihiko Gemma, Tesshi Yamada · 2015 · Journal of Thoracic Oncology
- Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of ExpandedTing Su, Michael Z. Ludwig, Jiajie Xu, Richard G. Fehon · 2017 · Developmental Cell
- Heterozygous Loss-of-Function Mutations in YAP1 Cause Both Isolated and Syndromic Optic Fissure Closure DefectsKathleen A. Williamson, Joe Rainger, James A. B. Floyd, Morad Ansari, Alison M. Meynert, Kishan Victoria Aldridge, Jacqueline K. Rainger, Carl A. Anderson, Anthony T. Moore, Matthew E. Hurles et al. · 2014 · The American Journal of Human Genetics
- Collagen synthesis disruption and downregulation of core elements of TGF-β, Hippo, and Wnt pathways in keratoconus corneasMichał Kabza, Justyna A. Karolak, Małgorzata Rydzanicz, Michał Wojciech Szcześniak, Dorota M. Nowak-Malczewska, Barbara Ginter-Matuszewska, Piotr Polakowski, Rafał Płoski, Jacek Paweł Szaflik, Marzena Gajęcka · 2017 · European Journal of Human Genetics
- Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalusRaehee Park, Uk Yeol Moon, Jun Yong Park, Lucinda J. Hughes, Randy L. Johnson, Seo‐Hee Cho, Seonhee Kim · 2016 · Nature Communications
- Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase ComplexZheng, Yonggang, Liu, Bo, Wang, Li, Lei, Huiyan, Pulgar Prieto, Katiuska Daniela, Pan, Duojia · 2017 · Cell Reports
- Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growthChiara V. Ragni, Nicolas Diguet, Jean‐François Le Garrec, Marta Novotová, Tatiana Pinho Resende, Sorin Pop, Nicolas Charon, Laurent Guillemot, Lisa Kitasato, Caroline Badouel et al. · 2017 · Nature Communications
- Salt-inducible kinases regulate growth through the Hippo signalling pathway in DrosophilaMichael C. Wehr, Maxine V. Holder, Ieva Gailite, Rebecca E. Saunders, Tobias M Maile, Elena Ciirdaeva, Rachael Instrell, Ming Jiang, Michael T. Howell, Moritz J. Rossner et al. · 2012 · Nature Cell Biology
- FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver TumorigenesisSuyuan Ji, Qingxu Liu, Shihao Zhang, Qinghua Chen, Cong Wang, Weiji Zhang, Xiao Chen, Yuxi Li, Cheng Nian, Jiaxin Li et al. · 2019 · Developmental Cell
- MST1 functions as a key modulator of neurodegeneration in a mouse model of ALSJae Keun Lee, Jin Hee Shin, Sang Gil Hwang, Byoung Joo Gwag, Ann Carolyn McKee, Jung-Hee Lee, Neil W. Kowall, Hoon Ryu, Dae‐Sik Lim, Eui‐Ju Choi · 2013 · Proceedings of the National Academy of Sciences
- The Roles of NDR Protein Kinases in Hippo SignallingAlexander Hergovich · 2016 · Genes
- Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZJing Yi, Li Lu, Kilangsungla Yanger, Wenqi Wang, Bo Hwa Sohn, Ben Z. Stanger, Min Zhang, James F. Martin, Jaffer A. Ajani, Junjie Chen et al. · 2016 · Hepatology
- Spectrin regulates Hippo signaling by modulating cortical actomyosin activityHua Deng, Wei Wang, Jianzhong Yu, Yonggang Zheng, Yun Qing, Duojia Pan · 2015 · eLife
- Mechanical strain regulates the Hippo pathway in DrosophilaGeorgina Fletcher, María-del-Carmen Díaz-de-la-Loza, Nerea Borreguero-Muñoz, Maxine V. Holder, Mario Aguilar‐Aragon, Barry J. Thompson · 2018 · Development
- Drosophila Pez Acts in Hippo Signaling to Restrict Intestinal Stem Cell ProliferationIngrid Poernbacher, Roland Baumgartner, Suresh Marada, Kevin A. Edwards, Hugo Stocker · 2012 · Current Biology
- The Cell Adhesion Molecule Echinoid Functions as a Tumor Suppressor and Upstream Regulator of the Hippo Signaling PathwayTao Yue, Aiguo Tian, Jin Jiang · 2012 · Developmental Cell
- High-Molecular-Weight Hyaluronan Is a Hippo Pathway Ligand Directing Cell Density-Dependent Growth Inhibition via PAR1bTakuya Ooki, Naoko Murata‐Kamiya, Atsushi Takahashi‐Kanemitsu, Weida Wu, Masanori Hatakeyama · 2019 · Developmental Cell
- R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical ActionabilityHsuan‐Yu Chen, Sung‐Liang Yu, Bing‐Ching Ho, Kang‐Yi Su, Yi‐Chiung Hsu, Chi-Sheng Chang, Yu-Cheng Li, Shi‐Yi Yang, Pin-Yen Hsu, Hao H. Ho et al. · 2015 · Journal of Clinical Oncology
- Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiationAtaaillah Benhaddou, Céline Keime, Tao Ye, Aurore Morlon, Isabelle Michel, Bernard Jost, Gabrielle Mengus, Irwin Davidson · 2011 · Cell Death and Differentiation
- Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5Lisheng Ni, Sheng Li, Jianzhong Yu, Jungki Min, Chad A. Brautigam, Diana R. Tomchick, Duojia Pan, Xuelian Luo · 2013 · Structure
- YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal MesenchymeJennifer L. Cotton, Qi Li, Lifang Ma, Joo‐Seop Park, Jiayi Wang, Jianhong Ou, Lihua Julie Zhu, Yicktung Tony Ip, Randy L. Johnson, Junhao Mao · 2017 · Developmental Cell
- Biallelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the KidneyRohit Mehra, Pankaj Vats, Marcin P. Cieslik, Xuhong Cao, Fengyun Su, Sudhanshu Kumar Shukla, Aaron M. Udager, Rui Wang, Jincheng Pan, Katayoon Kasaian et al. · 2016 · Cancer Discovery
- YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesisK. Taniguchi, Toshiro Moroishi, P. de Jong, M. Krawczyk, B. M. Grebbin, Hui-Yan Luo, Rui-Hua Xu, N. Golob-Schwarzl, C. Schweiger, Ke-Peng Wang et al. · 2017 · Proceedings of the National Academy of Sciences of the United States of America
- Opposite Feedbacks in the Hippo Pathway for Growth Control and Neural FateDavid Jukam, Baotong Xie, Jens Rister, David Terrell, Mark A. Charlton-Perkins, Daniela Pistillo, Brian A. Gebelein, Claude Desplan, Tiffany A. Cook · 2013 · Science
- The H ippo pathway in chemotherapeutic drug resistanceYulei Zhao, Xiaolong Yang · 2014 · International Journal of Cancer
- Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulationYoshitaka Sekido · 2011 · Pathology International
- Transcriptional integration of mitogenic and mechanical signals by Myc and YAPOttavio Croci, Serena Fazio, Francesca Biagioni, Elisa Donato, Marieta Cagánová, Laura Curti, Mirko Doni, Silvia Sberna, Deborah Aldeghi, Chiara Biancotto et al. · 2017 · Genes & Development
- A Sveinsson’s chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZMichinori Kitagawa · 2007 · Biochemical and Biophysical Research Communications
- Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathwayGao Liu, Fa‐Xing Yu, Young Chul Kim, Zhipeng Meng, Julián Naipauer, David J. Looney, Xiangguo Liu, Jorge Silvio Gutkind, Enrique A. Mesri, K-L Guan · 2014 · Oncogene
- Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylationFansen Meng, Ruyuan Zhou, Shiying Wu, Qian Zhang, Qiuheng Jin, Yao Zhou, Steven W. Plouffe, Shengduo Liu, Hai Song, Zongping Xia et al. · 2016 · Genes & Development
- The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growthFisun Hamaratoǧlu, Kathleen M. Gajewski, Leticia Sansores-García, Clayton M. Morrison, Chunyao Tao, Georg A. Halder · 2009 · Journal of Cell Science
- Yorkie Promotes Transcription by Recruiting a Histone Methyltransferase ComplexHyangyee Oh, Matthew G. Slattery, Lijia Ma, Kevin P. White, Richard S. Mann, Kenneth D. Irvine · 2014 · Cell Reports
- Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast FormationHelen McNeill, Antoine Reginensi · 2016 · Journal of the American Society of Nephrology
- The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6Yun Qing, Feng Yin, Wei Wang, Yonggang Zheng, Pengfei Guo, Frederick Schozer, Hua Deng, Duojia Pan · 2014 · eLife
- Hippo signaling in the kidney: the good and the badJenny Wong, Kristin A. Meliambro, Justina Ray, Kirk Nicholas Campbell · 2016 · American Journal of Physiology-Renal Physiology
- Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signalingYunyun Jin, Jinjin Xu, Meng-Xin Yin, Yi Lu, Lianxin Hu, Peixue Li, Peng Zhang, Zengqiang Yuan, Margaret Su-chun Ho, Hongbin Ji et al. · 2013 · eLife
- Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase WartsAlina M. Vrabioiu, Gary Struhl · 2015 · Developmental Cell
- The Hippo signaling pathway is required for salivary gland development and its dysregulation is associated with Sjogren's syndromeTone Bull Enger, Arman Samad-Zadeh, Meghan P. Bouchie, Kathrine Skarstein, Hilde Kanli Galtung, Toshiyuki Mera, Janice L. Walker, A. Sue Menko, Xaralabos Varelas, Denise Louise Faustman et al. · 2013 · Laboratory Investigation
- Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander diseaseLiqun Wang, Jing Xia, Jonathan Li, Tracy L. Hagemann, Jeffrey R. Jones, Ernest Fraenkel, David A. Weitz, Su‐Chun Zhang, Albee Messing, Mel Β. Feany · 2018 · Nature Communications
- Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous systemIeva Gailite, Birgit L. Aerne, Nicolas Tapon · 2015 · Proceedings of the National Academy of Sciences
- Scaling the Drosophila Wing: TOR-Dependent Target Gene Access by the Hippo Pathway Transducer YorkieJoseph Parker, Gary Struhl · 2015 · PLoS Biology
- From vestigial to vestigial-like: the Drosophila gene that has taken wingEmilie Simon, Corinne Faucheux, Alain Zider, Nadine Thézé, Pierre Thiébaud · 2016 · Development Genes and Evolution
- Big roles for Fat cadherinsSeth S. Blair, Helen McNeill · 2017 · Current Opinion in Cell Biology
- Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exitBrandon Nicolay, Battuya Bayarmagnai, Abul Bashar Mir Md. Khademul Islam, Núria López-Bigas, Maxim V. Frolov · 2011 · Genes & Development
- WW and C2 domain–containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathwayAnke Hermann, Dirk Oliver Wennmann, Sascha Gromnitza, Maria Edeling, Veerle Van Marck, Marius Sudol, Liliana Schaefer, Kerstin Duning, Thomas Weide, Hermann Josef Pavenstädt et al. · 2017 · Hepatology
- Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4KYong Suk Cho, Jian Zhu, Shuangxi Li, Bing Wang, Yuhong Han, Jin Jiang · 2018 · Nature Communications
- The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular glandAleksander D. Szymaniak, Rongjuan Mi, Shannon E. McCarthy, Adam C. Gower, Taylor L. Reynolds, Michaël Mingueneau, Maria A. Kukuruzinska, Xaralabos Varelas · 2017 · eLife
- The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafishJason Kuan Han Lai, Michelle M. Collins, Verónica Uribe, Vanesa Jiménez-Amilburu, Stefan Günther, Hans‐Martin Maischein, Didier Y. R. Stainier · 2018 · Development
- Making the Mouse BlastocystJanet Rossant · 2016 · Current topics in developmental biology/Current Topics in Developmental Biology
- Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth controlYavuz Kulaberoglu, Kui Lin, Maxine V. Holder, Zhongchao Gai, Marta Gómez-Ferrer, Belul Assefa Shifa, Merdiye Mavis, Lily Hoa, Ahmad A.D. Sharif, Celia Lujan et al. · 2017 · Nature Communications
- Fat-regulated adaptor protein Dlish binds the growth suppressor Expanded and controls its stability and ubiquitinationXing Wang, Yifei Zhang, Seth S. Blair · 2019 · Proceedings of the National Academy of Sciences
- Viral Small T Oncoproteins Transform Cells by Alleviating Hippo-Pathway-Mediated Inhibition of the YAP Proto-oncogeneThanh Nguyen, Xin Hong, Sam Tan, Qingfeng Chen, Lifang Chan, Marc L. Fivaz, Stephen Michael Cohen, Pieter Mathijs Voorhoeve · 2014 · Cell Reports
- Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet MassNicholas M. George, Brian P. Boerner, Shakeel U.R. Mir, Zachary P. Guinn, Nora Sarvetnick · 2015 · Molecular Endocrinology
- Nerfin-1 represses transcriptional output of Hippo signaling in cell competitionPengfei Guo, Chang-Hyun Lee, Huiyan Lei, Yonggang Zheng, Katiuska Daniela Pulgar Prieto, Duojia Pan · 2019 · eLife
- Disruption of mechanical stress in extracellular matrix is related to Stanford type A aortic dissection through down-regulation of Yes-associated proteinWenjian Jiang, Wei-Hong Ren, Xujie Liu, Yan Liu, Fujian Wu, Li‐Zhong Sun, Feng Lan, Jie Du, Hongjia Zhang · 2016 · Aging
- Validating upstream regulators of Yorkie activity in Hippo signaling through scalloped-based genetic epistasisJianzhong Yu, Duojia Pan · 2018 · Development