The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.
Cellular Mechanisms and Regulation of Quiescence
Open accessAbstract
Summary Quiescence is a state of reversible proliferative arrest in which cells are not actively dividing, and yet retain the capacity to reenter the cell cycle upon receiving an appropriate stimulus. Quiescent cells are remarkably diverse—they reside in different locations throughout the body, serve distinct roles, and are activated by a variety of signals. Despite this diversity, all quiescent cells must be able to persist in a non-dividing state without compromising their proliferative potential, which requires changes to core cellular programs. How drastically different cell types are able to implement extensive changes to their gene expression programs, metabolism, and cellular structures to induce a common cellular state is a fascinating question in cell and developmental biology. In this review, we explore the diversity of quiescent cells and highlight the unifying characteristics that define the quiescent state.
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Cites
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“Accordingly, both mitochondrial number and activity are reduced in quiescent cells (Figure 4), leading to decreased oxidative metabolism (Ho et al., 2017; Liang et al., 2020; Mohrin et al., 2018; Rodgers et al., 2014; Zhang et al., 2018).”
BackgroundInfluentialHEF1-Dependent Aurora A Activation Induces Disassembly of the Primary Cilium
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Cited by
Yuan, Z., Li, Y., Zhang, S., Wang, X., Dou, H., Yu, X., Zhang, Z., Yang, S., & Xiao, M. (2023) · Molecular Cancer · doi:10.1186/s12943-023-01744-8 · Cited by 977
Senescence and cancer — role and therapeutic opportunities
Schmitt, C. A., Wang, B., & Demaria, M. (2022) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-022-00668-4 · Cited by 794
Fernandez, B., Passanisi, V. J., Ashraf, H. M., & Spencer, S. L. (2025) · Nature Communications · doi:10.1038/s41467-025-66836-z · Cited by 18
Tup1 is critical for transcriptional repression in Quiescence in S. cerevisiae
(2022) · doi:10.1371/journal.pgen.1010559 · Cited by 13
Targeted Cancer Stem Cell Therapeutics: An Update
Fatima, N., Umar, M., Ambreen, S., Shaququzzaman, M., Alam, M. M., & Ali, R. (2025) · Current Topics in Medicinal Chemistry · doi:10.2174/0115680266275014240110071351 · Cited by 6
Metadata
- Authors
- Marescal, O., & Cheeseman, I. M.
- Venue
- Developmental Cell
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 55
- Issue
- 3
- Pages
- 259-271
- ISSN
- 1534-5807 (ISSN-L)
- OpenAlex
- W3103368541
- Cited by
- 292
- References
- 109
- FWCI
- 9.46
- Type
- journal article
- Language
- en
- Open access
- bronze
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