All-cause mortality after hypoglycemic and hyperglycemic emergencies among U.S. adults with diabetes, 2011–2020
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Estimated all-cause mortality within 30-days of hypoglycemic emergencies is 0.8 % in adults with type 1 diabetes and 1.7 % with type 2 diabetes; and within 30-days of hyperglycemic emergencies, it is 1.2 % with type 1 diabetes and 2.8 % with type 2 diabetes. These rates changed little between 2011 and 2020.
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Improvements in DKA mortality have plateaued in the past decade.
“these improvements have plateaued in the past decade (170,172,173).”
From 16. Diabetes Care in the Hospital: Standards of Care in Diabetes—2026 (2026) · cites this paper as [173]
The Methods (page not available) include DKA among hyperglycemic emergencies, and the Results (page not available) find no improvement in mortality after those emergencies for patients with type 1 diabetes from 2011 to 2020. But the study combines DKA with hyperglycemic hyperosmolar state rather than reporting a DKA-specific trend; for patients with type 2 diabetes, mortality after hyperglycemic emergencies increased. It measures all-cause mortality after an emergency, not mortality during DKA itself. (LLM, conf=0.86)
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- Authors
- McCoy, R. G., Herrin, J., Galindo, R. J., Sindhu Swarna, K., Umpierrez, G. E., Hill Golden, S., & O'Connor, P. J.
- Affiliations
- Mayo Clinic (US)
- Yale University (US)
- University of Miami (US)
- Grady Memorial Hospital (US)
- Corresponding author
- McCoy, Rozalina G.
- Venue
- Diabetes Research and Clinical Practice
- Publisher
- Elsevier BV
- Published
- 2023-03
- Volume
- 197
- Pages
- 110263
- ISSN
- 0168-8227 (ISSN-L)
- PMC
- PMC10023431
- OpenAlex
- W4318027339
- Cited by
- 20
- References
- 18
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 7 · 2023: 1
- FWCI
- 3.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 332 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Diabetes Research and Clinical Practice (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIDDK
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- all-cause mortality, hyperglycemic emergencies, type 1 diabetes, type 2 diabetes, diabetes complications, 30-day mortality, temporal trends
- MeSH terms
- Adult, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Emergencies, Humans, Hypoglycemic Agents, Diabetic Ketoacidosis
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