Cited by 201DNA Repair MechanismsDNA and Nucleic Acid ChemistryFungal and yeast genetics research

The DOI matches its Crossref record; 75 of the 79 references it cites were found in a registry or an index.

EXO1-A multi-tasking eukaryotic nuclease

Tran, Phuoc T., Erdeniz, Naz, Symington, Lorraine S., Liskay, R.Michael·2004·DNA Repair

DOI 10.1016/j.dnarep.2004.05.015

Open this paper in CoChat — free account

Abstract

Exo1 was first isolated as a 5' --> 3' exonuclease activity induced during meiosis in fission yeast and since that time has been implicated in a multitude of eukaryotic DNA metabolic pathways that include DNA repair, recombination, replication, and telomere integrity. Involvement in multiple pathways affecting genomic stability makes EXO1 a logical target for mutation during oncogenesis. Here, we review studies in several experimental systems that shed light on the role of Exo1 in these DNA transaction pathways, particularly those that may relate to oncogenesis.

Integrity signals

Registry

Crossref · 10.1016/j.dnarep.2004.05.015

Cites

75 of 75 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Global Mapping of the Yeast Genetic Interaction Network
Tong, A. H. Y., Lesage, G., Bader, G. D., Ding, H., Xu, H., Xin, X., Young, J., Berriz, G. F., Brost, R. L., Chang, M., et al. (2004) · Science · doi:10.1126/science.1091317 · Cited by 2,089
Meiosis-Specific DNA Double-Strand Breaks Are Catalyzed by Spo11, a Member of a Widely Conserved Protein Family
Keeney, S., Giroux, C. N., & Kleckner, N. E. (1997) · Cell · doi:10.1016/s0092-8674(00)81876-0 · Cited by 1,824
MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY
Modrich, P. L., & Lahue, R. S. (1996) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.65.070196.000533 · Cited by 1,510
TELOMERE LENGTH REGULATION
Greider, C. W. (1996) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.65.070196.002005 · Cited by 1,032
Eukaryotic DNA mismatch repair
Kolodner, R. D., & Marsischky, G. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80013-6 · Cited by 861
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
Sandell, L. J. (1993) · Cell · doi:10.1016/0092-8674(93)90493-a · Cited by 792
Single-Stranded DNA Arising at Telomeres in cdc13 Mutants May Constitute a Specific Signal for the RAD9 Checkpoint
Garvik, B. M., Carson, M., & Hartwell, L. H. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.11.6128 · Cited by 629
Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination
Alani, E. A., Padmore, R., & Kleckner, N. E. (1990) · Cell · doi:10.1016/0092-8674(90)90524-i · Cited by 613
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double‐strand break repair and serves as a barrier to error‐prone DNA repair pathways.
Boulton, S. J., & Jackson, S. P. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00890.x · Cited by 502
DNA Mismatch Repair: Molecular Mechanisms and Biological Function
Schofield, M. J., & Hsieh, P. (2003) · Annual Review of Microbiology · doi:10.1146/annurev.micro.57.030502.090847 · Cited by 498
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance
Boulton, S. J. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.23.4639 · Cited by 488
Mammalian DNA Mismatch Repair
Buermeyer, A. B., Deschênes, S. M., Baker, S. M., & Liskay, R. M. (1999) · Annual Review of Genetics · doi:10.1146/annurev.genet.33.1.533 · Cited by 448
Self-citation
The Nuclease Activity of Mre11 Is Required for Meiosis but Not for Mating Type Switching, End Joining, or Telomere Maintenance
Moreau, S., Ferguson, J. R., & Symington, L. S. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.556 · Cited by 447
Self-citation
The FEN‐1 family of structure‐specific nucleases in eukaryotic dna replication, recombination and repair
Lieber, M. R. (1997) · BioEssays · doi:10.1002/bies.950190309 · Cited by 446
A Novel Mutation Avoidance Mechanism Dependent on S. cerevisiae RAD27 Is Distinct from DNA Mismatch Repair
Tishkoff, D. X., Filosi, N., Gaida, G. M., & Kolodner, R. D. (1997) · Cell · doi:10.1016/s0092-8674(00)81846-2 · Cited by 435
MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.Preprint
Hollingsworth, N. M., Ponte, L. D., & Halsey, C. (1995) · Genes & Development · doi:10.1101/gad.9.14.1728 · Cited by 414
Saccharomyces telomeres acquire single-strand TG1–3 tails late in S phase
Wellinger, R. J., Wolf, A. J., & Zakian, V. A. (1993) · Cell · doi:10.1016/0092-8674(93)90049-v · Cited by 410
Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction
Ross‐Macdonald, P., & Roeder, G. S. (1994) · Cell · doi:10.1016/0092-8674(94)90037-x · Cited by 392
Identification and characterization of Saccharomyces cerevisiae EXO1 , a gene encoding an exonuclease that interacts with MSH2
Tishkoff, D. X., Boerger, A. L., Bertrand, P., Filosi, N., Gaida, G. M., Kane, M., & Kolodner, R. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7487 · Cited by 386
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterilityPreprint
Wei, K., Clark, A. B., Wong, E., Kane, M., Mazur, D. J., Parris, T., Kolas, N. K., Russell, R. G., Hou, H., Kneitz, B., et al. (2003) · Genes & Development · doi:10.1101/gad.1060603 · Cited by 327
EXO1 -dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70 Δ mutantsPreprint
Maringele, L., & Lydall, D. A. (2002) · Genes & Development · doi:10.1101/gad.225102 · Cited by 300
Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction
Wang, T., Kleckner, N. E., & Hunter, N. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.24.13914 · Cited by 291
Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination
Furuse, M., Nagase, Y., Tsubouchi, H., Murakami‐Murofushi, K., Shibata, T., & Ohta, K. (1998) · The EMBO Journal · doi:10.1093/emboj/17.21.6412 · Cited by 282
A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations
Huang, M., Rio, A.-G., Nicolas, A. G., & Kolodner, R. D. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2035018100 · Cited by 268
Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair
Genschel, J., Bazemore, L. R., & Modrich, P. L. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111854200 · Cited by 266
Mechanism of 5′-Directed Excision in Human Mismatch Repair
Genschel, J., & Modrich, P. L. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00428-3 · Cited by 254
DNA mismatch repair and mutation avoidance pathways
Marti, T. M., Kunz, C., & Fleck, O. (2002) · Journal of Cellular Physiology · doi:10.1002/jcp.10077 · Cited by 253
Mutations in XRS2 and RAD50 Delay but Do Not Prevent Mating-Type Switching in Saccharomyces cerevisiae
Ivanov, E. L., Sugawara, N., White, C. I., Fabre, F., & Haber, J. E. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.5.3414-3425.1994 · Cited by 243
The DNA-binding Protein Hdf1p (a Putative Ku Homologue) Is Required for Maintaining Normal Telomere Length in Saccharomyces Cerevisiae
Porter, S. E., Greenwell, P. W., Ritchie, K. B., & Petes, T. D. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.4.582 · Cited by 243
Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosis.Preprint
Hunter, N., & Borts, R. H. (1997) · Genes & Development · doi:10.1101/gad.11.12.1573 · Cited by 240
A Novel mre11 Mutation Impairs Processing of Double-Strand Breaks of DNA during Both Mitosis and Meiosis
Tsubouchi, H., & Ogawa, H. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.1.260 · Cited by 223
MEIOTIC GENE CONVERSION MUTANTS IN SACCHAROMYCES CEREVISIAE. I. ISOLATION AND CHARACTERIZATION OF pms1-1 AND pms1-2
Williamson, M. S., Game, J. C., & Fogel, S. (1985) · Genetics · doi:10.1093/genetics/110.4.609 · Cited by 220
Isolation of COM1, a New Gene Required to Complete Meiotic Double-Strand Break-Induced Recombination in Saccharomyces cerevisiae
Prinz, S., Amon, A., & Klein, F. (1997) · Genetics · doi:10.1093/genetics/146.3.781 · Cited by 218
Exo1 Roles for Repair of DNA Double-Strand Breaks and Meiotic Crossing Over inSaccharomyces cerevisiae
Tsubouchi, H., & Ogawa, H. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.7.2221 · Cited by 217
A Role for Exonuclease I from S. pombe in Mutation Avoidance and Mismatch Correction
Szankasi, P., & Smith, G. R. (1995) · Science · doi:10.1126/science.7855597 · Cited by 204
The 3′→5′ Exonucleases of DNA Polymerases δ and ɛ and the 5′→3′ Exonuclease Exo1 Have Major Roles in Postreplication Mutation Avoidance in Saccharomyces cerevisiae
Tran, H. T., Gordenin, D. A., & Resnick, M. A. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.3.2000 · Cited by 201
exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair
Amin, N. S., Nguyen, M.-N., Oh, S., & Kolodner, R. D. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.15.5142-5155.2001 · Cited by 198
Exonuclease I of Saccharomyces cerevisiae Functions in Mitotic Recombination In Vivo and In Vitro
Fiorentini, P., Huang, K. N., Tishkoff, D. X., Kolodner, R. D., & Symington, L. S. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.5.2764 · Cited by 198
Self-citation
DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray
Ooi, S. L., Shoemaker, D. D., & Boeke, J. D. (2003) · Nature Genetics · doi:10.1038/ng1258 · Cited by 195
A General Method for Identifying Recessive Diploid-Specific Mutations in Saccharomyces cerevisiae, Its Application to the Isolation of Mutants Blocked at Intermediate Stages of Meiotic Prophase and Characterization of a New Gene SAE2
McKee, A. H. Z., & Kleckner, N. E. (1997) · Genetics · doi:10.1093/genetics/146.3.797 · Cited by 191
Overlapping Functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 Nucleases in DNA Metabolism
Moreau, S., Morgan, E. A., & Symington, L. S. (2001) · Genetics · doi:10.1093/genetics/159.4.1423 · Cited by 176
Self-citation
The RAD2 Domain of Human Exonuclease 1 Exhibits 5′ to 3′ Exonuclease and Flap Structure-specific Endonuclease Activities
Lee, B.-I., & Wilson, D. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.53.37763 · Cited by 176
The Interaction of DNA Mismatch Repair Proteins with Human Exonuclease I
Schmütte, C., Sadoff, M. M., Shim, K.-S., Acharya, S., & Fishel, R. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102670200 · Cited by 167
Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms
Wu, Y., Mensink, R. G. J., Verlind, E., Sijmons, R. H., Buys, C. H. C. M., Hofstra, R. M. W., Berends, M. J. W., Kleibeuker, J. H., Post, J. G., Kempinga, C., et al. (2001) · Gastroenterology · doi:10.1053/gast.2001.25117 · Cited by 159
Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination.
Tishkoff, D. X., Amin, N. S., Viars, C. S., Arden, K. C., & Kolodner, R. D. (1998) · PubMed · Cited by 158
Human exonuclease I interacts with the mismatch repair protein hMSH2.
Schmütte, C., Marinescu, R. C., Sadoff, M. M., Guerrette, S., Overhauser, J., & Fishel, R. A. (1998) · PubMed · Cited by 156
Competition between the Rad50 Complex and the Ku Heterodimer Reveals a Role for Exo1 in Processing Double-Strand Breaks but Not Telomeres
Tomita, K., Matsuura, A., Caspari, T., Carr, A. M., Akamatsu, Y., Iwasaki, H., Mizuno, K., Ohta, K., Uritani, M., Ushimaru, T., et al. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5186-5197.2003 · Cited by 147
Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae
Tran, P. T., Erdeniz, N., Dudley, S., & Liskay, R. M. (2002) · DNA Repair · doi:10.1016/s1568-7864(02)00114-3 · Cited by 141
Self-citation
Redundant Exonuclease Involvement in Escherichia coli Methyl-directed Mismatch Repair
Viswanathan, M., Burdett, V., Baitinger, C., Modrich, P. L., & Lovett, S. T. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105481200 · Cited by 131
A DNA exonuclease induced during meiosis of Schizosaccharomyces pombe.
Szankasi, P., & Smith, G. R. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50688-3 · Cited by 127
Functional Domains of the Saccharomyces cerevisiae Mlh1p and Pms1p DNA Mismatch Repair Proteins and Their Relevance to Human Hereditary Nonpolyposis Colorectal Cancer-Associated Mutations
Pang, Q., Prolla, T. A., & Liskay, R. M. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.8.4465 · Cited by 126
Self-citation
Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae
Tran, P. T., Simon, J. A., & Liskay, R. M. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.161175998 · Cited by 126
Self-citation
Accumulation of Single-Stranded DNA and Destabilization of Telomeric Repeats in Yeast Mutant Strains Carrying a Deletion of RAD27
Parenteau, J., & Wellinger, R. J. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.6.4143 · Cited by 124
End Resection Initiates Genomic Instability in the Absence of Telomerase
Hackett, J. A., & Greider, C. W. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.23.8450-8461.2003 · Cited by 108
Human Exonuclease 1 Functionally Complements Its Yeast Homologues in DNA Recombination, RNA Primer Removal, and Mutation Avoidance
Qiu, J., Qian, Y., Chen, V., Guan, M., & Shen, B. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.25.17893 · Cited by 103
EXO1 Contributes to Telomere Maintenance in Both Telomerase-Proficient and Telomerase-Deficient Saccharomyces cerevisiae
Bertuch, A. A., & Lundblad, V. (2004) · Genetics · doi:10.1534/genetics.166.4.1651 · Cited by 97
Differential Suppression of DNA Repair Deficiencies of Yeast rad50, mre11 and xrs2 Mutants by EXO1 and TLC1 (the RNA Component of Telomerase)
Lewis, L. K., Karthikeyan, G., Westmoreland, J. W., & Resnick, M. A. (2002) · Genetics · doi:10.1093/genetics/160.1.49 · Cited by 94
Checkpoint-Dependent Activation of Mutagenic Repair in Saccharomyces cerevisiae pol3-01 Mutants
Datta, A., Schmeits, J. L., Amin, N. S., Lau, P. J., Myung, K., & Kolodner, R. D. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00058-7 · Cited by 91
EXO1 and MSH4 differentially affect crossing-over and segregation
Khazanehdari, K. A., & Borts, R. H. (2000) · Chromosoma · doi:10.1007/s004120050416 · Cited by 74
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer.
Jagmohan–Changur, S., Poikonen, T., Vilkki, S., Launonen, V., Wikman, F. P., Orntoft, T. F., Møller, P., Vasen, H. F. A., Tops, C. M. J., Kolodner, R. D., et al. (2003) · PubMed · Cited by 68
EXO1 Plays a Role in Generating Type I and Type II Survivors in Budding Yeast
Maringele, L. (2004) · Genetics · doi:10.1534/genetics.166.4.1641 · Cited by 68
Decreased Meiotic Intergenic Recombination and Increased Meiosis I Nondisjunction in exo1 Mutants of Saccharomyces cerevisiae
Kirkpatrick, D. T., Ferguson, J. R., Petes, T. D., & Symington, L. S. (2000) · Genetics · doi:10.1093/genetics/156.4.1549 · Cited by 67
Self-citation
EXO1 and MSH6 Are High-Copy Suppressors of Conditional Mutations in the MSH2 Mismatch Repair Gene of Saccharomyces cerevisiae
Sokolsky, T. D., & Alani, E. (2000) · Genetics · doi:10.1093/genetics/155.2.589 · Cited by 65
Alteration of gene conversion tract length and associated crossing over during plasmid gap repair in nuclease-deficient strains of Saccharomyces cerevisiae
Symington, L. S. (2000) · Nucleic Acids Research · doi:10.1093/nar/28.23.4649 · Cited by 56
Self-citation
The Saccharomyces cerevisiae mre11(ts) Allele Confers a Separation of DNA Repair and Telomere Maintenance Functions
Chamankhah, M., Fontanie, T., & Xiao, W. (2000) · Genetics · doi:10.1093/genetics/155.2.569 · Cited by 47
Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome.
Sun, X., Zheng, L., & Shen, B. (2002) · PubMed · Cited by 44
Tosca:ADrosophilaGene Encoding a Nuclease Specifically Expressed in the Female Germline
Digilio, F. A., Pannuti, A., Lucchesi, J. C., Furia, M., & Polito, L. C. (1996) · Developmental Biology · doi:10.1006/dbio.1996.0200 · Cited by 43
Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair
Qiu, J. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.13.3077 · Cited by 42
Ntg2p, a Saccharomyces cerevisiae DNAN-Glycosylase/Apurinic or Apyrimidinic Lyase Involved in Base Excision Repair of Oxidative DNA Damage, Interacts with the DNA Mismatch Repair Protein Mlh1p
Gellon, L., Werner, M., & Boiteux, S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202963200 · Cited by 40
A 5'-3' Exonuclease From Saccharomyces cerevisiae is Required for in Vitro Recombination Between Linear DNA Molecules with Overlapping Homology
Huang, K. N., & Symington, L. S. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3125-3134.1993 · Cited by 34
Self-citation
Schizosaccharomyces pombe exo1 is involved in the same mismatch repair pathway as msh2 and pms1
Rudolph, C., Fleck, O., & Kohli, J. (1998) · Current Genetics · doi:10.1007/s002940050405 · Cited by 31
Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability
Alam, N. A., Gorman, P., Jaeger, E. E. M., Kelsell, D. P., Leigh, I. M., Ratnavel, R. C., Murdoch, M. E., Houlston, R. S., Aaltonen, L. A., Roylance, R. R., et al. (2003) · Cancer Genetics and Cytogenetics · doi:10.1016/s0165-4608(03)00196-1 · Cited by 29
Control of GT Repeat Stability in Schizosaccharomyces pombe by Mismatch Repair Factors
Mansour, A. A., Tornier, C., Lehmann, E., Darmon, M. Y., & Fleck, O. (2001) · Genetics · doi:10.1093/genetics/158.1.77 · Cited by 27
A 5'-3' exonuclease from Saccharomyces cerevisiae is required for in vitro recombination between linear DNA molecules with overlapping homology.
Huang, K. N., & Symington, L. S. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.6.3125 · Cited by 24
Self-citation
Topical Reversion at the HIS1 Locus of Saccharomyces cerevisiae • A Tale of Three Mutants
von Borstel, R. C., Savage, E. A., Wang, Q., Hennig, U. G. G., Ritzel, R. G., Lee, G. S. F., Hamilton, M. D., Chrenek, M. A., Tomaszewski, R., Higgins, J. A., et al. (1998) · Genetics · doi:10.1093/genetics/148.4.1647 · Cited by 15

Sorted by citations

Double-Strand Break End Resection and Repair Pathway Choice
Symington, L. S., & Gautier, J. (2011) · Annual Review of Genetics · doi:10.1146/annurev-genet-110410-132435 · Cited by 1,556
Self-citation
Mechanisms and functions of DNA mismatch repair
Li, G. (2007) · Cell Research · doi:10.1038/cr.2007.115 · Cited by 1,479
The multifaceted mismatch-repair system
Jiricny, J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1907 · Cited by 1,375
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Mimitou, E. P., & Symington, L. S. (2008) · Nature · doi:10.1038/nature07312 · Cited by 1,060
Self-citation
DNA helicases Sgs1 and BLM promote DNA double-strand break resectionPreprint
Gravel, S., Chapman, J. R., Magill, C. P., & Jackson, S. P. (2008) · Genes & Development · doi:10.1101/gad.503108 · Cited by 595

See all 201

Authors: Tran, P. T., Erdeniz, N., Symington, L. S., & Liskay, R. M.
Affiliations: St. Mary's Medical Center (US)
Oregon Health & Science University (US)
Columbia University (US)
Corresponding author: Liskay, R.Michael
ORCID: Tran, Phuoc T.
Symington, Lorraine S.
Venue: DNA Repair
Publisher: Elsevier BV
Published: 2004-12
Volume: 3
Issue: 12
Pages: 1549-1559
ISSN: 1568-7856 (ISSN-L)
1568-7864
DOI: 10.1016/j.dnarep.2004.05.015
OpenAlex: W2019394964
Cited by: 201
References: 79
Citations by year: 2026: 4 · 2025: 5 · 2024: 5 · 2023: 7 · 2022: 2 · 2021: 7 · 2020: 6 · 2019: 9 · 2018: 5 · 2017: 13 · 2016: 10 · 2015: 14 · 2014: 16 · 2013: 14 · 2012: 9
FWCI: 0.63
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: DNA repair (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of General Medical Sciences (GM41784, GM 45413, R01GM045413, R01GM041784)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Keywords: EXO1, exonuclease, DNA recombination, DNA replication, telomere integrity, genome stability, carcinogenesis, meiosis, Schizosaccharomyces pombe, DNA metabolism
MeSH terms: Amino Acid Sequence, Animals, DNA Repair, Exodeoxyribonucleases, Humans, Molecular Sequence Data, Mutation, Neoplasms, Recombination, Genetic, Saccharomyces cerevisiae, Telomere, Protein Structure, Tertiary, DNA Repair Enzymes

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

EXO1-A multi-tasking eukaryotic nuclease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks