The DOI matches its Crossref record; 75 of the 79 references it cites were found in a registry or an index.
EXO1-A multi-tasking eukaryotic nuclease
Abstract
Exo1 was first isolated as a 5' --> 3' exonuclease activity induced during meiosis in fission yeast and since that time has been implicated in a multitude of eukaryotic DNA metabolic pathways that include DNA repair, recombination, replication, and telomere integrity. Involvement in multiple pathways affecting genomic stability makes EXO1 a logical target for mutation during oncogenesis. Here, we review studies in several experimental systems that shed light on the role of Exo1 in these DNA transaction pathways, particularly those that may relate to oncogenesis.
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In the citing paper
“Experiments performed in yeast cells have suggested that in CLUV conditions no checkpoint is activated, not even during S phase; indeed, checkpoint deficient strains do not exhibit sensitivity to CLUV treatment [62].”
From Mind the gap: keeping UV lesions in check (2011) · cites this paper as [62]
In the citing paper
“Experiments performed in yeast cells have suggested that in CLUV conditions no checkpoint is activated, not even during S phase; indeed, checkpoint deficient strains do not exhibit sensitivity to CLUV treatment [62].”
From Mind the gap: keeping UV lesions in check (2011) · cites this paper as [62]
In the citing paper
“Even more surprisingly, NER is not important in these conditions, since NER-deficient cells are also not sensitive to CLUV.”
From Mind the gap: keeping UV lesions in check (2011) · cites this paper as [62]
Citations
Cites
Global Mapping of the Yeast Genetic Interaction Network
Tong, A. H. Y., Lesage, G., Bader, G. D., Ding, H., Xu, H., Xin, X., Young, J., Berriz, G. F., Brost, R. L., Chang, M., et al. (2004) · Science · doi:10.1126/science.1091317 · Cited by 2,089
Keeney, S., Giroux, C. N., & Kleckner, N. E. (1997) · Cell · doi:10.1016/s0092-8674(00)81876-0 · Cited by 1,824
MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY
Modrich, P. L., & Lahue, R. S. (1996) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.65.070196.000533 · Cited by 1,510
Greider, C. W. (1996) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.65.070196.002005 · Cited by 1,032
Eukaryotic DNA mismatch repair
Kolodner, R. D., & Marsischky, G. (1999) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(99)80013-6 · Cited by 861
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
Sandell, L. J. (1993) · Cell · doi:10.1016/0092-8674(93)90493-a · Cited by 792
Garvik, B. M., Carson, M., & Hartwell, L. H. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.11.6128 · Cited by 629
Alani, E. A., Padmore, R., & Kleckner, N. E. (1990) · Cell · doi:10.1016/0092-8674(90)90524-i · Cited by 613
Boulton, S. J., & Jackson, S. P. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00890.x · Cited by 502
DNA Mismatch Repair: Molecular Mechanisms and Biological Function
Schofield, M. J., & Hsieh, P. (2003) · Annual Review of Microbiology · doi:10.1146/annurev.micro.57.030502.090847 · Cited by 498
Cited by
Sorted by citations
Double-Strand Break End Resection and Repair Pathway Choice
Symington, L. S., & Gautier, J. (2011) · Annual Review of Genetics · doi:10.1146/annurev-genet-110410-132435 · Cited by 1,556
Self-citationMechanisms and functions of DNA mismatch repair
Li, G. (2007) · Cell Research · doi:10.1038/cr.2007.115 · Cited by 1,479
The multifaceted mismatch-repair system
Jiricny, J. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1907 · Cited by 1,375
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Mimitou, E. P., & Symington, L. S. (2008) · Nature · doi:10.1038/nature07312 · Cited by 1,060
Self-citationDNA helicases Sgs1 and BLM promote DNA double-strand break resectionPreprint
Gravel, S., Chapman, J. R., Magill, C. P., & Jackson, S. P. (2008) · Genes & Development · doi:10.1101/gad.503108 · Cited by 595
Metadata
- Authors
- Tran, P. T., Erdeniz, N., Symington, L. S., & Liskay, R. M.
- Affiliations
- St. Mary's Medical Center (US)
- Oregon Health & Science University (US)
- Columbia University (US)
- Corresponding author
- Liskay, R.Michael
- Venue
- DNA Repair
- Publisher
- Elsevier BV
- Published
- 2004-12
- Volume
- 3
- Issue
- 12
- Pages
- 1549-1559
- ISSN
- 1568-7856 (ISSN-L)
- 1568-7864
- OpenAlex
- W2019394964
- Cited by
- 201
- References
- 79
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 5 · 2023: 7 · 2022: 2 · 2021: 7 · 2020: 6 · 2019: 9 · 2018: 5 · 2017: 13 · 2016: 10 · 2015: 14 · 2014: 16 · 2013: 14 · 2012: 9
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- DNA repair (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of General Medical Sciences (GM41784, GM 45413, R01GM045413, R01GM041784)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Keywords
- EXO1, exonuclease, DNA recombination, DNA replication, telomere integrity, genome stability, carcinogenesis, meiosis, Schizosaccharomyces pombe, DNA metabolism
- MeSH terms
- Amino Acid Sequence, Animals, DNA Repair, Exodeoxyribonucleases, Humans, Molecular Sequence Data, Mutation, Neoplasms, Recombination, Genetic, Saccharomyces cerevisiae, Telomere, Protein Structure, Tertiary, DNA Repair Enzymes
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