The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
Pharmaceutical cocrystals: from serendipity to design to application
Open accessAbstract
The field of pharmaceutical cocrystals has reached a tipping point, particularly because cocrystals can improve the physicochemical properties of drugs without compromising their therapeutic benefit. Accounts of cocrystal investigations in the literature started in earnest in 2003 and patent applications soon followed. The frequency of both has steadily accelerated, demonstrating an enhanced understanding of the design, characterisation, and manufacture of cocrystals and heightened interest from industry. Indeed, there were four new product approvals from 2014 to 2017 and more are in the pipeline. Here, we review all marketed drug products that are based upon pharmaceutical cocrystal drug substances, starting with the first recorded example, Beta-Chlor® in 1963, with a particular emphasis on their discovery, rationale for use, and market impact.
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Cites
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DiMasi, J. A., Grabowski, H. G., & Hansen, R. W. (2016) · Journal of Health Economics · doi:10.1016/j.jhealeco.2016.01.012 · Cited by 3,359
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Pharmaceutical cocrystals: along the path to improved medicines
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Cited by
Structural Analysis of Molecular Materials Using the Pair Distribution Function
Terban, M. W., & Billinge, S. J. L. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00237 · Cited by 426
Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications
Guo, M., Sun, X., Chen, J., & Cai, T. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.03.030 · Cited by 386
Metadata
- Authors
- Kavanagh, O. N., Croker, D. M., Walker, G. M., & Zaworotko, M. J.
- Venue
- Drug Discovery Today
- Publisher
- Elsevier BV
- Published
- 2019-03
- Volume
- 24
- Issue
- 3
- Pages
- 796-804
- ISSN
- 1359-6446 (ISSN-L)
- OpenAlex
- W2902359770
- Cited by
- 323
- References
- 32
- FWCI
- 18.24
- Type
- journal article
- Language
- en
- Open access
- green
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
