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Gender differences in cannabis use disorders: Results from the National Epidemiologic Survey of Alcohol and Related Conditions
Open accessAbstract
Background To examine gender differences among individuals diagnosed with DSM-IV lifetime cannabis use disorder (CUD).Methods A nationally representative sample of U.S. adults aged 18 years or older that were diagnosed with lifetime CUD (n=3297): Men (n=2080), Women (n=1217). Data were drawn from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC, n=43,093). The survey response rate was 81%.Results Nearly all individuals with CUD had a psychiatric comorbidity (95.6% of men, 94.1% of women). Men with lifetime CUD were more likely than women to be diagnosed with any psychiatric disorder, any substance use disorder and antisocial personality disorder, whereas women with CUD had more mood and anxiety disorders. After adjusting for gender differences in sociodemographic correlates and the prevalence of psychiatric disorders in the general population, women with CUD were at greater risk for externalizing disorders. Men with CUD met more criteria for cannabis abuse, had longer episodes of CUD, smoked more joints, and were older at remission when compared to women with CUD. Women experienced telescoping to CUD. Treatment-seeking rates were very low for both genders, and there were no gender differences in types of services used or reasons for not seeking treatment.Conclusions There are important gender differences in the clinical characteristics and psychiatric comorbidities among individuals with CUD.
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“Patterns of comorbidity also vary between men and women: men are more likely to have multiple SUDs, while women tend to have greater rates of mood, anxiety and eating dis orders in addition to a SUD 330,333 .”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [333]
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“This is particularly concerning because, for many (although not all) substances, women progress more rapidly from use to SUD 332,333 .”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [333]
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Metadata
- Authors
- Khan, S. S., Secades-Villa, R., Okuda, M., Wang, S., Pérez-Fuentes, G., Kerridge, B. T., & Blanco, C.
- Affiliations
- New York State Psychiatric Institute (US)
- University of Maryland, College Park (US)
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2013-06
- Volume
- 130
- Issue
- 1-3
- Pages
- 101-108
- ISSN
- 0376-8716 (ISSN-L)
- PMC
- PMC3586748
- OpenAlex
- W2030628632
- Cited by
- 293
- References
- 87
- Citations by year
- 2026: 24 · 2025: 26 · 2024: 22 · 2023: 32 · 2022: 25 · 2021: 33 · 2020: 29 · 2019: 16 · 2018: 17 · 2017: 24 · 2016: 19 · 2015: 14 · 2014: 8 · 2013: 3
- FWCI
- 5.87
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educación, Cultura y Deporte) (submittedVersion, cc-by-nc-nd)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- National Institutes of Health (CA133050, DA019606, DA020783-S4, DA023200, DA023973)
- National Institute on Drug Abuse
- National Institute on Alcohol Abuse and Alcoholism
- New York State Psychiatric Institute
- Ministerio de Educación, Cultura y Deporte (PR2010-0501)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- cannabis use disorder, gender differences, psychiatric comorbidity, substance use disorders, antisocial personality disorder, mood disorders, anxiety disorders, treatment seeking, telescoping, externalizing disorders, NESARC
- MeSH terms
- Adolescent, Alcoholism, Mental Disorders, Marijuana Abuse, Female, Health Surveys, Humans, Male, Sex Characteristics, United States, Young Adult
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