Lifetime Co-occurrence of DSM-III-R Alcohol Abuse and Dependence With Other Psychiatric Disorders in the National Comorbidity Survey
Abstract
OBJECTIVE: To study patterns of co-occurrence of lifetime DSM-III-R alcohol disorders in a household sample. METHODS: Data came from the National Comorbidity Survey (NCS), a nationally representative household survey. Diagnoses were based on a modified version of the Composite International Diagnostic Interview. RESULTS: Respondents with lifetime NCS/DSM-III-R alcohol abuse or dependence had a high probability of carrying at least 1 other lifetime NCS/DSM-III-R diagnosis. Retrospective reports have suggested that most lifetime co-occurring alcohol disorders begin at a later age than at least 1 other NCS/DSM-III-R disorder. Earlier disorders are generally stronger predictors of alcohol dependence than alcohol abuse and stronger among women than men. Lifetime co-occurrence is positively, but weakly, associated with the persistence of alcohol abuse among men and of alcohol dependence among both men and women. CONCLUSIONS: Caution is needed in interpreting the results due to the fact that diagnoses were made by nonclinicians and results are based on retrospective reports of the age at onset. Within the context of these limitations, though, these results show that alcohol abuse and dependence are often associated with other lifetime DSM-III-R disorders and suggest that, at least in recent cohorts, the alcohol use disorders are usually temporally secondary. Prospective data and data based on clinically confirmed diagnoses are needed to verify these findings.
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High rates of comorbid anxiety and depression have been found in various samples of individuals with alcohol use disorders.
“High rates of comorbid anxiety and depression have been found in various samples of individuals with alcohol use disorders (Kessler et al., 1997).”
From Differences in help seeking rates after brief intervention for alcohol use disorders in general practice patients with and without comorbid anxiety or depressive disorders (2008) · cites this paper as Kessler et al., 1997
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- Authors
- Kessler, R. C.
- Affiliations
- Harvard University (US)
- Corresponding author
- Kessler, Ronald C.
- ORCID
- Kessler, Ronald C.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1997-04-01
- Volume
- 54
- Issue
- 4
- Pages
- 313
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2124876944
- Cited by
- 2,085
- References
- 33
- Citations by year
- 2026: 12 · 2025: 35 · 2024: 35 · 2023: 31 · 2022: 38 · 2021: 50 · 2020: 75 · 2019: 93 · 2018: 45 · 2017: 55 · 2016: 69 · 2015: 86 · 2014: 85 · 2013: 106 · 2012: 96
- FWCI
- 39.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (K20AA000168, K20-AA00168)
- National Institute of Mental Health (R01MH046376, R01 MH46376, K01 MH00507)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- alcohol abuse, alcoholism, psychiatric comorbidity, age of onset, sex differences, National Comorbidity Survey, household surveys
- MeSH terms
- Alcoholism, Mental Disorders, Female, Health Surveys, Humans, Male, Probability, Retrospective Studies, Sex Factors, United States, Comorbidity, Prevalence, Age of Onset
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