Characterizing pain and associated coping strategies in methadone and buprenorphine-maintained patients
Open accessAbstract
Background Chronic pain is common among patients receiving opioid maintenance treatment (OMT) for opioid use disorder. To aid development of treatment recommendations for coexisting pain and opioid use disorder, it is necessary to characterize pain treatment needs and assess whether needs differ as a function of OMT medication. Methods A point-prevalence survey assessing pain and engagement in coping strategies was administered to 179 methadone and buprenorphine-maintained patients. Results Forty-two percent of participants were categorized as having chronic pain. Methadone patients had greater severity of pain relative to buprenorphine patients, though both groups reported high levels of interference with daily activities, and participants with pain attended the emergency room more frequently relative to participants without pain. Only 2 coping strategies were being utilized by more than 50% of participants (over-the-counter medication, prayer). Conclusions Results indicate that pain among OMT patients is common, severe, and of significant impairment. Methadone patients reported greater severity pain, particularly worse pain in the past 24h, though interference from pain in daily activities did not vary as a function of OMT. Most participants with pain were utilizing few evidenced-based pain coping strategies. Increasing OMT patient access to additional pain treatment strategies is an opportunity for immediate intervention, and similarities across OMT type suggest interventions do not need to be customized to methadone vs. buprenorphine patients.
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There is high co-occurrence of CP and SUDs.
“given the high co-occurrence of CP and SUDs 61”
From The Effectiveness of Interventions for Improving Chronic Pain Symptoms Among People With Mental Illness: A Systematic Review (2024) · cites this paper as [61]
The Results (§3.1) report chronic pain in 41.9% of participants receiving treatment for opioid use disorder, supporting substantial co-occurrence in that group. The claim extends this finding to substance use disorders generally, which the study did not assess. (LLM, conf=0.82)
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Self-citationDunn, K. E., Ashworth, J., & Strain, E. C. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197618431.013.14
Self-citationSkjærvø, I., Marciuch, A., Digranes, L. C. W., Follerås, L. M. G., Mordal, J., Solli, K. K., Abel, E. K. F., Amundsen, K., Egeland, K. M., Haugen, B. K., et al. (2025) · JMIR Research Protocols · doi:10.2196/67663
- Authors
- Dunn, K. E., Finan, P. H., Tompkins, D. A., Fingerhood, M., & Strain, E. C.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Dunn, Kelly E.
- Venue
- Drug and Alcohol Dependence
- Publisher
- Elsevier BV
- Published
- 2015-12
- Volume
- 157
- Pages
- 143-149
- ISSN
- 0376-8716 (ISSN-L)
- PMC
- PMC4663104
- OpenAlex
- W2109838101
- Cited by
- 50
- References
- 44
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 6 · 2023: 6 · 2022: 4 · 2021: 9 · 2020: 6 · 2019: 7 · 2018: 7 · 2017: 1 · 2016: 2
- FWCI
- 3.57
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Drug and Alcohol Dependence (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institutes of Health (4k24da023186-10)
- National Institute on Drug Abuse (K24-DA023186, R21DA035327, K23DA029609, K23DA035915, R01DA035246)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- chronic pain, opioid use disorder, opioid maintenance treatment, methadone, buprenorphine, pain coping, pain intensity, interference with daily activities, emergency department visits, over-the-counter drugs, prayer
- MeSH terms
- Adaptation, Psychological, Adult, Analgesics, Opioid, Buprenorphine, Female, Humans, Male, Methadone, Middle Aged, Opioid-Related Disorders, Prevalence, Pain Threshold, Chronic Pain, Pain Management, Maintenance Chemotherapy
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