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Initiation into prescription opioid misuse amongst young injection drug users
Open accessAbstract
Background Prescription opioids are the most frequently misused class of prescription drugs amongst young adults. Initiation into prescription opioid misuse is an important public health concern since opioids are increasingly associated with drug dependence and fatal overdose. Descriptive data about initiation into prescription opioid misuse amongst young injection drug users (IDUs) are scarce.Methods An exploratory qualitative study was undertaken to describe patterns of initiation into prescription opioid misuse amongst IDUs aged 16-25 years. Those young IDUs who had misused a prescription drug at least three times in the past three months were recruited during 2008 and 2009 in Los Angeles (n=25) and New York (n=25). Informed by an ethno-epidemiological approach, descriptive data from a semi-structured interview guide were analysed both quantitatively and qualitatively.Results Initiation into prescription opioid misuse was facilitated by easy access to opioids via participant's own prescription, family, or friends, and occurred earlier than misuse of other illicit drugs, such as heroin. Nearly all transitioned into sniffing opioids, most injected opioids, and many initiated injection drug use with an opioid. Motives for transitions to sniffing and injecting opioids included obtaining a more potent high and/or substituting for heroin; access to multiple sources of opioids was common amongst those who progressed to sniffing and injecting opioids.Conclusion Prescription opioid misuse was a key feature of trajectories into injection drug use and/or heroin use amongst this sample of young IDUs. A new pattern of drug use may be emerging whereby IDUs initiate prescription opioid misuse before using heroin.
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“Non medical use of pharmaceutical opioids leading to injection heroin use and concomitant use of heroin and pharmaceuticals opioids have been reported (Siegal et al., 1994; Lankenau et al., 2012; Nielsen et al., 2011; Wilkins et al., 2011).”
From National trends in pharmaceutical opioid related overdose deaths compared to other substance related overdose deaths: 1999-2009. (2013) · cites this paper as Lankenau et al., 2012
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Let’s Talk about Pain Medicines – Workshops on the Safe and Effective Use of Prescription Opioids
LaScala, K., Hudson, S., & Mowatt, C. (2019) · Journal of Consumer Health on the Internet · doi:10.1080/15398285.2019.1646584
“Most young adults who turn to using heroin start out by using the opioids they find in their homes (Jones 2013; Lankenau et al. 2012).”
BackgroundPolicies affecting the supply and access of opioid analgesics
Chiu, K., McDonald, S., Legg, T., Karanges, E. A., & Bero, L. A. (2019) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-d-19-00095
Smith, K. E. (2019) · ThinkIR: The University of Louisville's Institutional Repository (University of Louisville) · doi:10.18297/etd/3259
Evidence-Based Guidelines for Opioid Therapy in Pediatrics
Tham, S. W., Groenewald, C. B., & Walco, G. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-36287-4_5
Premkumar, A., Speedy, S. E., & Miller, E. S. (2020) · American Journal of Perinatology Reports · doi:10.1055/s-0040-1708492
A Mathematical Model of the Opioid Epidemic in the State of Maine
Butler, C. D. (2020) · DigitalCommons (California Polytechnic State University)
Three Essays on Health Economics and Policy Evaluation
Shakya, S. (2020) · doi:10.33915/etd.7767
Compton, W. M., & Blanco, C. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.001
Novel Psychoactive Substances: A New Challenge for Prevention and Treatment
Kapitány‐Fövény, M., Corazza, O., Marrinan, S., & Demetrovics, Z. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.032
Human Laboratory Paradigms in Addictions Research
Morris, V. L., Arshad, F., Balodis, I. M., Reed, D. D., MacKillop, J. M., & Amlung, M. T. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.010
Anhedonia in Addictive Behaviors
Dyer, W. G., Leventhal, A. M., Goldenson, N. I., & Bello, M. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.039
American Legal Issues in Addiction Treatment and Research
Willick, D. H. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.041
Strack, R. W., Orsini, M. M., Ewald, D. R., & Scheier, L. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.019
Soehnlen, N. T., Erb, E., Kiskaddon, E. M., Green, U., Froehle, A. W., & Krishnamurthy, A. (2020) · doi:10.21203/rs.3.rs-87056/v1
“Page 8/12 Ease of access to opioids is a risk factor for opioid abuse, which itself is a risk factor for subsequent heroin use[1, 2].”
BackgroundYoung Women and the Initiation Trajectory of Prescription Opioid Misuse
Chernick, R. (2021) · CUNY Academic Works (City University of New York)
Naltrexone for adolescent opioid use disorder: a bridge in the treatment gap?
LaCasse, M., & Quigley, J. M. (2021) · Journal of Substance Use · doi:10.1080/14659891.2021.1941351
“The mean age of onset of opioid misuse in this sample was 13.9 years while the mean age of onset of opioid injection and heroin injection were 16.6 years and 17.9 years, respectively (Lankenau et al., 2012).”
BackgroundInfluentialOpioids and Young Adults in Alaska: Access, Consumption, Consequences, and Perceptions
Richie, A., Hanson, B. L., & Davis, K. E. (2020) · ScholarWorks - UA (University of Alaska System)
Metadata
- Authors
- Lankenau, S. E., Teti, M., Silva, K., Bloom, J. J., Harocopos, A., & Treese, M.
- Affiliations
- Drexel University (US)
- University of Missouri (US)
- Children's Hospital Los Angeles (US)
- National Development and Research Institutes (US)
- Corresponding author
- Lankenau, Stephen E.
- Venue
- International Journal of Drug Policy
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 23
- Issue
- 1
- Pages
- 37-44
- ISSN
- 0955-3959 (ISSN-L)
- PMC
- PMC3196821
- OpenAlex
- W2128960742
- Cited by
- 440
- References
- 71
- Citations by year
- 2026: 5 · 2025: 17 · 2024: 13 · 2023: 19 · 2022: 22 · 2021: 30 · 2020: 84 · 2019: 46 · 2018: 35 · 2017: 34 · 2016: 33 · 2015: 35 · 2014: 27 · 2013: 27 · 2012: 11
- FWCI
- 20.73
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- International Journal of Drug Policy (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (DA021299)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- prescription opioid misuse, intravenous drug use, young adults, opioid initiation, heroin use, substance use trajectories, opioid access, drug addiction, opioid overdose, illicit drug use
- MeSH terms
- Adolescent, Adolescent Behavior, Adult, Age Factors, Analgesics, Opioid, Heroin, Family, Family Health, Female, Humans, Male, Opioid-Related Disorders, New York City, Surveys and Questionnaires, Los Angeles, Substance Abuse, Intravenous, Friends, Prescription Drugs, Young Adult, Drug-Seeking Behavior
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