The DOI matches its Crossref record; 70 of the 71 references it cites were found in a registry or an index.
Initiation into prescription opioid misuse amongst young injection drug users
Open accessAbstract
Background Prescription opioids are the most frequently misused class of prescription drugs amongst young adults. Initiation into prescription opioid misuse is an important public health concern since opioids are increasingly associated with drug dependence and fatal overdose. Descriptive data about initiation into prescription opioid misuse amongst young injection drug users (IDUs) are scarce.Methods An exploratory qualitative study was undertaken to describe patterns of initiation into prescription opioid misuse amongst IDUs aged 16-25 years. Those young IDUs who had misused a prescription drug at least three times in the past three months were recruited during 2008 and 2009 in Los Angeles (n=25) and New York (n=25). Informed by an ethno-epidemiological approach, descriptive data from a semi-structured interview guide were analysed both quantitatively and qualitatively.Results Initiation into prescription opioid misuse was facilitated by easy access to opioids via participant's own prescription, family, or friends, and occurred earlier than misuse of other illicit drugs, such as heroin. Nearly all transitioned into sniffing opioids, most injected opioids, and many initiated injection drug use with an opioid. Motives for transitions to sniffing and injecting opioids included obtaining a more potent high and/or substituting for heroin; access to multiple sources of opioids was common amongst those who progressed to sniffing and injecting opioids.Conclusion Prescription opioid misuse was a key feature of trajectories into injection drug use and/or heroin use amongst this sample of young IDUs. A new pattern of drug use may be emerging whereby IDUs initiate prescription opioid misuse before using heroin.
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“Non medical use of pharmaceutical opioids leading to injection heroin use and concomitant use of heroin and pharmaceuticals opioids have been reported (Siegal et al., 1994; Lankenau et al., 2012; Nielsen et al., 2011; Wilkins et al., 2011).”
From National trends in pharmaceutical opioid related overdose deaths compared to other substance related overdose deaths: 1999-2009. (2013) · cites this paper as Lankenau et al., 2012
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Cites
Monitoring the Future: National Results on Adolescent Drug Use: Overview of Key Findings
Johnston, L. D., O’Malley, P. M., Bachman, J. G., & Schulenberg, J. E. (2003) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1037/e560352009-001 · Cited by 6,930
Snowball Sampling: Problems and Techniques of Chain Referral Sampling
Biernacki, P., & Waldorf, D. (1981) · Sociological Methods & Research · doi:10.1177/004912418101000205 · Cited by 6,001 · cited 1×
“Following the CAP, ethnographers sampled young IDUs using a combination of targeted sampling (Watters & Biernacki, 1989) and chain referral sampling (Biernacki & Waldorf, 1981; Penrod et al., 2003).”
Anderson, E. N. (1977) · eScholarship (California Digital Library) · Cited by 2,567
Targeted Sampling: Options for the Study of Hidden Populations
Watters, J. K., & Biernacki, P. (1989) · Social Problems · doi:10.2307/800824 · Cited by 1,534 · cited 1×
“Following the CAP, ethnographers sampled young IDUs using a combination of targeted sampling (Watters & Biernacki, 1989) and chain referral sampling (Biernacki & Waldorf, 1981; Penrod et al., 2003).”
Results from the 2003 National Survey on Drug Use and Health: National Findings
(2004) · PsycEXTRA Dataset · doi:10.1037/e400442005-001 · Cited by 1,245
Illegal leisure the normalization of adolescent recreational drug use
Parker, H. J., Aldridge, J. A., & Measham, F. C. (1998) · doi:10.4324/9781315812441 · Cited by 640
A Discussion of Chain Referral As a Method of Sampling Hard-to-Reach Populations
Penrod, J., Preston, D. B., Cain, R. E., & Starks, M. T. (2003) · Journal of Transcultural Nursing · doi:10.1177/1043659602250614 · Cited by 528 · cited 1×
“Following the CAP, ethnographers sampled young IDUs using a combination of targeted sampling (Watters & Biernacki, 1989) and chain referral sampling (Biernacki & Waldorf, 1981; Penrod et al., 2003).”
Thorpe, L. E. (2002) · American Journal of Epidemiology · doi:10.1093/aje/155.7.645 · Cited by 446 · cited 1×
“…aged 30 and younger who currently inject drugs (e.g., Fuller et al., 2001; Roy et al., 2007; Page et al., 2009; Hagan et al., 2010) - are a particularly high-risk subgroup of adolescents and young adults (Thorpe et al., 2002; Davidson et al., 2002; Miller et al., 2004; Rondinelli et al., 2009).”
Medical Use, Illicit Use, and Diversion of Abusable Prescription Drugs
McCabe, S. E., Teter, C. J., & Boyd, C. J. (2006) · Journal of American College Health · doi:10.3200/jach.54.5.269-278 · Cited by 366 · cited 1×
“Additionally, the young people clearly regarded prescription opioids – regardless of source – as readily accessible, valued commodities that could be traded or sold (McCabe et al. 2006).”
Page, K. A., Hahn, J. A., Evans, J. L., Shiboski, S. C., Lum, P. J., Delwart, E., Tobler, L. H., Andrews, W. J., Avanesyan, L., Cooper, S., et al. (2009) · The Journal of Infectious Diseases · doi:10.1086/605947 · Cited by 285 · cited 1×
“Young injection drugs users (IDUs) – persons aged 30 and younger who currently inject drugs (e.g., Fuller et al., 2001; Roy et al., 2007; Page et al., 2009; Hagan et al., 2010) - are a particularly high-risk subgroup of adolescents and young adults (Thorpe et al., 2002; Davidson et al., 2002;…”
Research works printed but not linked: 1
- Clatts, 1995, Hitting a moving target: The use of ethnographic methods in the evaluation of AIDS outreach programs for homeless youth in NYC. Qualitative Methods in Drug Abuse and HIV Research, NIDA Research Monograph, 157, 117
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Items 401–439 of 439
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Patient Knowledge of Opioid Usage and Side Effects Prior to Surgery
Duncan, A., Alameddine, M. B., Baerg, T., Arora, N. S., Cottrell, H., Sekhri, S., Hallway, A. K., Howard, R., & Waljee, J. F. (2021) · Michigan Journal of Medicine · doi:10.3998/mjm.1436
Pistas para ahorrar en la producción de un mailing
Tobalina, J. A. (1995) · MK: Marketing + ventas
Córdoba-Grueso, W. S., Peck, K. R., Eddens, K. S., & Parker, M. A. (2021) · Drug and Alcohol Dependence Reports · doi:10.1016/j.dadr.2021.100022
Clinical and Research Methods in the Addictions
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.008
Levels of Analysis and Etiology
(2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.014
Ongoing and Future Research Directions
(2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.030
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.002
Srivastava, A. B., & Gold, M. S. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.033
Sussman, S. Y. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108632591.042
Are Opioids Really Needed After Pediatric Surgery? A Mini-Review
Reeson, E. A. (2022) · Archives of Pediatrics · doi:10.29011/2575-825x.100207
“Furthermore, 75% of young adults who use intravenous opioids reported opioid misuse that began with prescription opioids [26].”
BackgroundPostop analgesia in Saudi Arabia and the United States: A resident’s perspective
Akbar, H. N. (2022) · Current Psychiatry · doi:10.12788/cp.0298
Patterns of opioid misuse initiation among African-Americans
Rigg, K. K., & Strickland, S. L. (2023) · Drugs Education Prevention and Policy · doi:10.1080/09687637.2023.2173050
“OMI during adolescence is often described as beginning in middle/high school, often coinciding with first use of alcohol or marijuana (Lankenau et al., 2012).”
BackgroundAbusing Illicit Drug: Systemic and Orofacial Health Complications
(2022) · Journal of Oral & Dental Health · doi:10.33140/jodh.06.03.02
Epidemiology of Opioid Use and Smoking, Alcohol, and Polysubstance Use Among Persons Using Opioids
Parker, M. A., & Córdoba-Grueso, W. S. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780197618431.013.2
Batra, N. N., Rees, C. A., Luong, P. M., Phan, C. T., Abazari, A., & Zegans, M. E. (2023) · Research Square · doi:10.21203/rs.3.rs-2966311/v1
(2023) · Journal of Addiction Science · doi:10.17756/jas.2023-60
“While there are multiple substance use trajectories, several studies have reported initiation with prescription opioid NMU prior to transitioning to illicit drugs [17-22], however most did not study the trajectory of routes of administration used with prescription opioid NMU which may contribute to the understanding o…”
BackgroundGreen, J. L., Dailey-Govoni, T., & Vosburg, S. K. (2023) · Journal of Addiction Science · doi:10.17756/jas.2023-060
Reducing Opioid Use in the Postpartum Patient: A Retrospective Study on a Single Center Intervention
Sheikh, A., Patel, R., Lirio, P., Nguyen, E. S., & Rodriguez, M. H. (2024) · Journal of the Osteopathic Family Physicians of California · doi:10.58858/010201
Causation and common liability in the progression of the United States opioid crisis
Dash, G. F. (2024) · MOspace Institutional Repository (University of Missouri) · doi:10.32469/10355/105877
Pain Management in Oculofacial Surgery
Marous, C. L., & Wladis, E. J. (2025) · Springer eBooks · doi:10.1007/978-3-031-63178-8_5
Changing Postoperative Opioid Prescribing Practices
Keane, O. A., & Kelley‐Quon, L. I. (2025) · Difficult decisions in surgery: an evidence-based approach · doi:10.1007/978-3-031-80468-7_45
Courchesne‐Krak, N. S., Chandrasekaran, A. R., Gonzalez, J., Bianchi, S. B., Tran, V., Johnson, E. O., Troiani, V., Hettema, J. M., Stein, M. B., Coon, H. H., et al. (2025) · Complex Psychiatry · doi:10.1159/000546389
“Many studies reported the continuous nonmedical use of opioids among persons who misuse opioids as an attempt to get high, improve sleep, decrease anxiety, feel psycho-logically “ normal, ” and other motives [19, 154 – 156].”
Postoperative Pain and Opioid Use in Urogynecology Patients
Divirgilio, L., Long, J. B., & Boyd, S. S. (2025) · Anesthesia Research · doi:10.3390/anesthres2040021
“Postoperatively, they found that a one-point increase in Fibromyalgia Score was associated with a 30.8 increase in mean morphine equivalents used two weeks after procedure ( p 0.001) [4].”
InfluentialAn Orally Administered Misuse Deterrent Opioid Prodrug for Treatment of Acute Pain
Rose, D. A., Treacy, J. W., Seth, K., Tanzillo, A. F., Li, A., Tamshen, K., Sloan, L. K., Boehnke, N., Evans, C. J., Cahill, C. M., et al. (2025) · JACS Au · doi:10.1021/jacsau.5c01126
Martel‐Laferrière, V., Feaster, D. J., Metsch, L. R., Schackman, B. R., Loignon, C., Nosyk, B., Tookes, H. E., Behrends, C. N., Arruda, N., Adigun, O., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19642102
Schifanella, R., Vedove, D. D., Salomone, A., Bajardi, P., & Paolotti, D. (2020) · Figshare · doi:10.6084/m9.figshare.12308288
Schifanella, R., Vedove, D. D., Salomone, A., Bajardi, P., & Paolotti, D. (2020) · Figshare · doi:10.6084/m9.figshare.12308276
Martel‐Laferrière, V., Feaster, D. J., Metsch, L. R., Schackman, B. R., Loignon, C., Nosyk, B., Tookes, H. E., Behrends, C. N., Arruda, N., Adigun, O., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19642105
Schifanella, R., Vedove, D. D., Salomone, A., Bajardi, P., & Paolotti, D. (2020) · Figshare · doi:10.6084/m9.figshare.12308294
Martel‐Laferrière, V., Feaster, D. J., Metsch, L. R., Schackman, B. R., Loignon, C., Nosyk, B., Tookes, H. E., Behrends, C. N., Arruda, N., Adigun, O., et al. (2022) · Figshare · doi:10.6084/m9.figshare.19642108
Schifanella, R., Vedove, D. D., Salomone, A., Bajardi, P., & Paolotti, D. (2020) · Figshare · doi:10.6084/m9.figshare.12308282
Gallagher, C. A., Chandler, D. J., & Manvich, D. F. (2026) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2026.113030
“Initial opioid use often begins with prescription opioids (POs) prior to the development of opioid use disorder (OUD) (Dickson-Gomez et al., 2022; Jones, 2013; Lankenau et al., 2012; Veliz et al., 2022).”
Elbur, A. I., Suprasert, B., Mirzazadeh, A., Wilson, E. C., & McFarland, W. (2026) · Addictive Behaviors Reports · doi:10.1016/j.abrep.2026.100706
“Younger age, lower educational attainment, and adverse childhood experiences have been associated with earlier onset of drug use (Sosnowski et al., 2022; Powell, 2023; Lankenau et al., 2012).”
Corbett, C. M., O’Shall, A. E., Niedringhaus, M. S., & West, E. A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.02.729613
“Only a subset of individuals prescribed oxycodone will abuse the drug 47,48 , indicating individual differences in the motivation to obtain and continue to use oxycodone after prescriptions have ended.”
Khan, I., Jhanjee, S., Dhawan, A., & Afroz, O. (2026) · Industrial Psychiatry Journal · doi:10.4103/ipj.ipj_481_25
Metadata
- Authors
- Lankenau, S. E., Teti, M., Silva, K., Bloom, J. J., Harocopos, A., & Treese, M.
- Affiliations
- Drexel University (US)
- University of Missouri (US)
- Children's Hospital Los Angeles (US)
- National Development and Research Institutes (US)
- Corresponding author
- Lankenau, Stephen E.
- Venue
- International Journal of Drug Policy
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 23
- Issue
- 1
- Pages
- 37-44
- ISSN
- 0955-3959 (ISSN-L)
- PMC
- PMC3196821
- OpenAlex
- W2128960742
- Cited by
- 440
- References
- 71
- Citations by year
- 2026: 5 · 2025: 17 · 2024: 13 · 2023: 19 · 2022: 22 · 2021: 30 · 2020: 84 · 2019: 46 · 2018: 35 · 2017: 34 · 2016: 33 · 2015: 35 · 2014: 27 · 2013: 27 · 2012: 11
- FWCI
- 20.73
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- International Journal of Drug Policy (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (DA021299)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- prescription opioid misuse, intravenous drug use, young adults, opioid initiation, heroin use, substance use trajectories, opioid access, drug addiction, opioid overdose, illicit drug use
- MeSH terms
- Adolescent, Adolescent Behavior, Adult, Age Factors, Analgesics, Opioid, Heroin, Family, Family Health, Female, Humans, Male, Opioid-Related Disorders, New York City, Surveys and Questionnaires, Los Angeles, Substance Abuse, Intravenous, Friends, Prescription Drugs, Young Adult, Drug-Seeking Behavior
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