Characterizing Multimorbidity from Type 2 Diabetes
Open accessAbstract
Patients with type 2 diabetes mellitus (T2DM) often live with and develop multiple co-occurring conditions, namely multimorbidity, with diffuse impacts on clinical care and patient quality of life. However, literature characterizing T2DM-related multimorbidity patterns is limited. This review summarizes the findings from the emerging literature characterizing and quantifying the association of T2DM with multimorbidity clusters. The authors' findings reveal 3 dominant cluster types appearing in patients with T2DM-related multimorbidity, such as cardiometabolic precursor conditions, vascular conditions, and mental health conditions. The authors recommend that holistic patient care centers around early detection of other comorbidities and consideration of wider risk factors.
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Patients diagnosed with type 2 diabetes are often at risk of developing multiple additional comorbidities.
“Patients diagnosed with type 2 diabetes are often at risk of developing multiple additional comorbidities (Cicek et al., 2021).”
From Artificial intelligence based prediction models for individuals at risk of multiple diabetic complications: A systematic review of the literature (2022) · cites this paper as Cicek et al., 2021
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- Authors
- Cicek, M., Buckley, J., Pearson-Stuttard, J., & Gregg, E. W.
- Affiliations
- Imperial College London (GB)
- MRC Centre for Environment and Health (GB)
- Corresponding author
- Cicek, Meryem
- Venue
- Endocrinology and Metabolism Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2021-09
- Volume
- 50
- Issue
- 3
- Pages
- 531-558
- ISSN
- 0889-8529 (ISSN-L)
- PMC
- PMC8383848
- OpenAlex
- W3193683671
- Cited by
- 91
- References
- 46
- Citations by year
- 2026: 26 · 2025: 31 · 2024: 19 · 2023: 9 · 2022: 6
- FWCI
- 1.30
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Endocrinology and Metabolism Clinics of North America (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Spiral (Imperial College London) (submittedVersion, other-oa)
- Funders
- Medical Research Council (MR/V005057/1)
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- type 2 diabetes, multimorbidity, multimorbidity clusters, vascular conditions, psychiatric comorbidity, comorbidity patterns, holistic care
- MeSH terms
- Multimorbidity, Diabetes Mellitus, Type 2, Humans, Quality of Life, Comorbidity, Cluster Analysis
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