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Cited by 305

The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Atherothrombosis: A widespread disease with unpredictable and life-threatening consequences*1

Open access
VILESGONZALEZ, J·2004·European Heart Journal

Abstract

Atherothrombosis, characterised by atherosclerotic lesion disruption with superimposed thrombus formation, is the major cause of acute coronary syndromes (ACS) and cardiovascular death. It is the leading cause of mortality in the industrialised world. Atherosclerosis is a diffuse process that starts early in childhood and progresses asymptomatically through adult life. Later in life, it is clinically manifested as coronary artery disease, stroke, transient ischaemic attack, and peripheral arterial disease. From the clinical point of view, we should envision this disease as a single pathologic entity that affects different vascular territories. Available antithrombotic therapy is very safe and efficient but the morbidity and mortality due to atherothrombosis is still unacceptably high. Recent evidence suggests that inhibition of tissue factor or elements in the tissue factor pathway (i.e., factors VIIa and Xa, or thrombin) has the potential to further improve outcomes in atherothrombosis. Here, we will review the most important concepts and advances in the pathogenesis, prevention, and antithrombotic treatment of this widespread disease.

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Metadata

Authors
VILESGONZALEZ, J.
Venue
European Heart Journal
Published
2004-07
Volume
25
Issue
14
Pages
1197-1207
ISSN
0195-668X (ISSN-L)
OpenAlex
W2112995033
Cited by
305
References
94
FWCI
10.57
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Atherothrombosis: A widespread disease with unpredictable and life-threatening consequences*1. https://app.cochat.ai/papers/10.1016/j.ehj.2004.03.011
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VILESGONZALEZ, J. (2004). Atherothrombosis: A widespread disease with unpredictable and life-threatening consequences*1. European Heart Journal. https://doi.org/10.1016/j.ehj.2004.03.011

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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