The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Decreased Cardiac Output, Venous Congestion and the Association with Renal Impairment in Patients with Cardiac Dysfunction
Open accessAbstract
Background: Renal failure in heart failure is related to decreased cardiac output. However, little is known about its association with venous congestion. Aims: To investigate the relationship between venous congestion and glomerular filtration rate (GFR) in patients with cardiac dysfunction. Methods and results: Right atrial pressure (RAP) and cardiac index (CI) were determined by right heart catheterisation in 51 patients with cardiac dysfunction, secondary to pulmonary hypertension. GFR and renal blood flow (RBF) were measured as 125I-Iothalamate and 131I-Hippuran clearances, respectively. Mean age was 40±11 years and 69% of patients were female. GFR was 73±19 ml/min/1.73 m2 with a CI of 2.1±0.7 l/min/m2. In multivariate analysis, RBF (r=0.664, p<0.001) and RAP (r<0.367, p=0.020) were independently associated with GFR. In patients in the lower ranges of RBF, venous congestion was an important determinant of renal function. Conclusion: RBF is the main factor determining GFR in patients with cardiac dysfunction. Venous congestion, characterised by an increased RAP, adjusted for RBF is also related to GFR. Treatment to preserve GFR should not only focus on improvement of renal perfusion, but also on decreasing venous congestion.
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Cites
Renal Function as a Predictor of Outcome in a Broad Spectrum of Patients With Heart Failure
Hillege, H. L., Nitsch, D., Pfeffer, M. A., Swedberg, K., McMurray, J. J. V., Yusuf, S., Granger, C. B., Michelson, E. L., Östergren, J., Cornel, J. H., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.580506 · Cited by 945
Self-citationBlantz, R. C., Konnen, K. S., & Tucker, B. J. (1976) · Journal of Clinical Investigation · doi:10.1172/jci108293 · Cited by 428
Cited by
Damman, K., van Deursen, V. M., Navis, G., Voors, A. A., van Veldhuisen, D. J., & Hillege, H. L. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.08.080 · Cited by 986
Self-citationHarjola, V.-P., Mebazaa, A., Čelutkienė, J., Bettex, D., Bueno, H., Chioncel, O., Crespo-Leiro, M. G., Falk, V., Filippatos, G., Gibbs, S., et al. (2016) · European Journal of Heart Failure · doi:10.1002/ejhf.478 · Cited by 720
Beaubien-Souligny, W., Rola, P., Haycock, K., Bouchard, J., Lamarche, Y., Spiegel, R., & Denault, A. Y. (2020) · The Ultrasound Journal · doi:10.1186/s13089-020-00163-w · Cited by 698
Gheorghiade, M., & Pang, P. S. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.041 · Cited by 600
Calzavacca, P., Licari, E., & Bellomo, R. (2010) · Surgical Intensive Care Medicine · doi:10.1007/978-0-387-77893-8_38 · Cited by 533
Metadata
- Authors
- Damman, K., Navis, G., Smilde, T. D. J., Voors, A. A., van der Bij, W., van Veldhuisen, D. J., & Hillege, H. L.
- Venue
- European Journal of Heart Failure
- Publisher
- Oxford University Press (OUP)
- Published
- 2007-08-31
- Volume
- 9
- Issue
- 9
- Pages
- 872-878
- ISSN
- 1388-9842 (ISSN-L)
- 1879-0844
- OpenAlex
- W2002747645
- Cited by
- 471
- References
- 2
- FWCI
- 13.82
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Damman, K., Navis, G., Smilde, T. D. J., Voors, A. A., van der Bij, W., van Veldhuisen, D. J., & Hillege, H. L. (2007). Decreased Cardiac Output, Venous Congestion and the Association with Renal Impairment in Patients with Cardiac Dysfunction. European Journal of Heart Failure. https://doi.org/10.1016/j.ejheart.2007.05.010
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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