Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease

Cited by (127)

Items 101–127 of 127

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8. Interactions-guided blueprint of acetylcholinesterase binding: A review on structural and molecular determinants
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11. BindingDB Entry 50015896: Alzheimer's disease: Updated multi-targets therapeutics are in clinical and in progress.
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12. BindingDB Entry 50009030: Development of the "hidden" multifunctional agents for Alzheimer's disease.
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13. BindingDB Entry 50013892: Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.
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14. BindingDB Entry 50019625: Multi-target potential of newly designed tacrine-derived cholinesterase inhibitors: Synthesis, computational and pharmacological study.
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15. BindingDB Entry 50023002: Discovery of novel substituted (Z)-N'-hydroxy-3-(3-phenylureido)benzimidamide derivatives as multifunctional molecules targeting pathological hallmarks of Alzheimer's disease.
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16. BindingDB Entry 50023783: Novel multipotent conjugate bearing tacrine and donepezil motifs with dual cholinergic inhibition and neuroprotective properties targeting Alzheimer's disease.
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17. BindingDB Entry 50013955: Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.
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18. BindingDB Entry 50020718: Novel drug-like fluorenyl derivatives as selective butyrylcholinesterase and β-amyloid inhibitors for the treatment of Alzheimer's disease.
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19. BindingDB Entry 50019402: Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease.
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20. BindingDB Entry 50009034: Investigating 1,2,3,4,5,6-hexahydroazepino[4,3-b]indole as scaffold of butyrylcholinesterase-selective inhibitors with additional neuroprotective activities for Alzheimer's disease.
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21. BindingDB Entry 50022005: Enhanced Recognition Memory through Dual Modulation of Brain Carbonic Anhydrases and Cholinesterases.
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22. BindingDB Entry 50013796: Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors.
    BindingDB · 2022 · UC San Diego
23. BindingDB Entry 50016452: Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease.
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24. BindingDB Entry 50017995: Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease.
    BindingDB · 2023 · UC San Diego
25. BindingDB Entry 50013302: Design, synthesis and biological evaluation of novel naturally-inspired multifunctional molecules for the management of Alzheimer's disease.
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26. BindingDB Entry 50023018: Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies.
    BindingDB · 2026 · UC San Diego
27. BindingDB Entry 50021430: Design, synthesis and biological evaluation of carbamate derivatives incorporating multifunctional carrier scaffolds as pseudo-irreversible cholinesterase inhibitors for the treatment of Alzheimer's disease.
    BindingDB · 2025 · UC San Diego