The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Antibacterial activity study of 1,2,4-triazole derivatives
Abstract
Antibiotics are commonly used to fight against bacterial infections, but bacteria have already been resistant to almost all antibiotics due to abuse of antibiotics. 1,2,4-Triazole derived compounds possess chemotherapeutic effects including potential antibacterial activities against drug-sensitive as well as drug-resistant pathogens. Hybridization displays a high potential to develop novel drugs with the capacity to overcome drug resistance, reduce toxicity and improve pharmacokinetic profiles. More effective antibacterial candidates might be obtained by the hybridization of 1,2,4-triazole with other antibacterial pharmacophores. This review summarizes the recent advances of 1,2,4-triazole derivatives as potential antibacterial compounds, and the structure-activity relationship is also discussed.
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Cites
Hybrid Molecules with a Dual Mode of Action: Dream or Reality?
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Quinolines and structurally related heterocycles as antimalarials
Kaur, K., Jain, M., Reddy, R. P., & Jain, R. (2010) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2010.04.011 · Cited by 727
Natural Products as Platforms To Overcome Antibiotic Resistance
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Heterocycles in drugs and drug discovery
Gomtsyan, A. R. (2012) · Chemistry of Heterocyclic Compounds · doi:10.1007/s10593-012-0960-z · Cited by 615
Hybrid molecules: The privileged scaffolds for various pharmaceuticals
Shaveta, Mishra, S., & Singh, P. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.08.039 · Cited by 508
Ciprofloxacin derivatives and their antibacterial activities
Zhang, G.-F., Liu, X., Zhang, S., Pan, B., & Liu, M.-L. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.01.078 · Cited by 390
Quinoline hybrids and their antiplasmodial and antimalarial activities
Hu, Y.-Q., Gao, C., Zhang, S., Xu, L., Xu, Z., Feng, L.-S., Wu, X., & Zhao, F. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.07.061 · Cited by 380
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Quinoline-based antimalarial hybrid compounds
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Metadata
- Authors
- Gao, F., Wang, T., Xiao, J., & Huang, G.
- Venue
- European Journal of Medicinal Chemistry
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 173
- Pages
- 274-281
- ISSN
- 0223-5234 (ISSN-L)
- OpenAlex
- W2938466059
- Cited by
- 305
- References
- 45
- FWCI
- 12.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gao, F., Wang, T., Xiao, J., & Huang, G. (2019). Antibacterial activity study of 1,2,4-triazole derivatives. European Journal of Medicinal Chemistry. https://doi.org/10.1016/j.ejmech.2019.04.043
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