Radiomics in radiooncology – challenging the medical physicist
Abstract
Purpose Noticing the fast growing translation of artificial intelligence (AI) technologies to medical image analysis this paper emphasizes the future role of the medical physicist in this evolving field. Specific challenges are addressed when implementing big data concepts with high-throughput image data processing like radiomics and machine learning in a radiooncology environment to support clinical decisions.Methods Based on the experience of our interdisciplinary radiomics working group, techniques for processing minable data, extracting radiomics features and associating this information with clinical, physical and biological data for the development of prediction models are described. A special emphasis was placed on the potential clinical significance of such an approach.Results Clinical studies demonstrate the role of radiomics analysis as an additional independent source of information with the potential to influence the radiooncology practice, i.e. to predict patient prognosis, treatment response and underlying genetic changes. Extending the radiomics approach to integrate imaging, clinical, genetic and dosimetric data ('panomics') challenges the medical physicist as member of the radiooncology team.Conclusions The new field of big data processing in radiooncology offers opportunities to support clinical decisions, to improve predicting treatment outcome and to stimulate fundamental research on radiation response both of tumor and normal tissue. The integration of physical data (e.g. treatment planning, dosimetric, image guidance data) demands an involvement of the medical physicist in the radiomics approach of radiooncology. To cope with this challenge national and international organizations for medical physics should organize more training opportunities in artificial intelligence technologies in radiooncology.
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- Authors
- Peeken, J. C., Bernhofer, M., Wiestler, B., Goldberg, T., Cremers, D., Rost, B., Wilkens, J. J., Combs, S. E., & Nüsslin, F.
- Affiliations
- TUM Klinikum (DE)
- Technical University of Munich (DE)
- Corresponding author
- Nüsslin, Fridtjof
- ORCID
- Venue
- Physica Medica
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 48
- Pages
- 27-36
- ISSN
- 1120-1797 (ISSN-L)
- OpenAlex
- W2794993152
- Cited by
- 98
- References
- 110
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 14 · 2023: 10 · 2022: 18 · 2021: 15 · 2020: 15 · 2019: 9 · 2018: 9
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physica Medica (publishedVersion)
- PubMed (publishedVersion)
- mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
- Site cant be reached (submittedVersion)
- PuSH - Publication Server of Helmholtz Zentrum München (submittedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
- Keywords
- radiomics, radiation oncology, medical physicist role, artificial intelligence in medical imaging, treatment outcome prediction, outcome prediction, treatment response prediction, genetic alterations, big data, machine learning, radiation response, clinical decision support, medical physics training
- MeSH terms
- Artificial Intelligence, Diagnostic Imaging, Humans, Image Processing, Computer-Assisted, Neoplasms, Physics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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