Cited by 98Radiomics and Machine Learning in Medical ImagingArtificial Intelligence in Healthcare and EducationAdvanced Radiotherapy Techniques

Radiomics in radiooncology – challenging the medical physicist

Peeken, Jan C., Bernhofer, Michael, Wiestler, Benedikt, Goldberg, Tatyana, Cremers, Daniel, Rost, Burkhard, Wilkens, Jan J., Combs, Stephanie E. +1 more·2018·Physica Medica

Abstract

Purpose Noticing the fast growing translation of artificial intelligence (AI) technologies to medical image analysis this paper emphasizes the future role of the medical physicist in this evolving field. Specific challenges are addressed when implementing big data concepts with high-throughput image data processing like radiomics and machine learning in a radiooncology environment to support clinical decisions.Methods Based on the experience of our interdisciplinary radiomics working group, techniques for processing minable data, extracting radiomics features and associating this information with clinical, physical and biological data for the development of prediction models are described. A special emphasis was placed on the potential clinical significance of such an approach.Results Clinical studies demonstrate the role of radiomics analysis as an additional independent source of information with the potential to influence the radiooncology practice, i.e. to predict patient prognosis, treatment response and underlying genetic changes. Extending the radiomics approach to integrate imaging, clinical, genetic and dosimetric data ('panomics') challenges the medical physicist as member of the radiooncology team.Conclusions The new field of big data processing in radiooncology offers opportunities to support clinical decisions, to improve predicting treatment outcome and to stimulate fundamental research on radiation response both of tumor and normal tissue. The integration of physical data (e.g. treatment planning, dosimetric, image guidance data) demands an involvement of the medical physicist in the radiomics approach of radiooncology. To cope with this challenge national and international organizations for medical physics should organize more training opportunities in artificial intelligence technologies in radiooncology.

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Crossref · 10.1016/j.ejmp.2018.03.012

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Authors
Peeken, J. C., Bernhofer, M., Wiestler, B., Goldberg, T., Cremers, D., Rost, B., Wilkens, J. J., Combs, S. E., & Nüsslin, F.
Affiliations
  • TUM Klinikum (DE)
  • Technical University of Munich (DE)
Corresponding author
Nüsslin, Fridtjof
Venue
Physica Medica
Publisher
Elsevier BV
Published
2018-04
Volume
48
Pages
27-36
ISSN
1120-1797 (ISSN-L)
OpenAlex
W2794993152
Cited by
98
References
110
Citations by year
2026: 2 · 2025: 6 · 2024: 14 · 2023: 10 · 2022: 18 · 2021: 15 · 2020: 15 · 2019: 9 · 2018: 9
FWCI
1.87
Type
journal article
Language
en
Open access
closed
Locations
  • Physica Medica (publishedVersion)
  • PubMed (publishedVersion)
  • mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
  • Site cant be reached (submittedVersion)
  • PuSH - Publication Server of Helmholtz Zentrum München (submittedVersion)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
Keywords
radiomics, radiation oncology, medical physicist role, artificial intelligence in medical imaging, treatment outcome prediction, outcome prediction, treatment response prediction, genetic alterations, big data, machine learning, radiation response, clinical decision support, medical physics training
MeSH terms
Artificial Intelligence, Diagnostic Imaging, Humans, Image Processing, Computer-Assisted, Neoplasms, Physics

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