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Cited by 290

The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.

The effect of symptom clusters on functional status and quality of life in women with breast cancer

Open access
Dodd, Marylin J., Cho, Maria H., Cooper, Bruce A., Miaskowski, Christine·2010·European Journal of Oncology Nursing
DOI 10.1016/j.ejon.2009.09.005
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Abstract

Purpose The purposes of this study of women with breast cancer receiving chemotherapy with/without radiation therapy were to determine whether: 1) subgroups of oncology outpatients can be identified based on a specific symptom cluster (i.e., pain, fatigue, sleep disturbances, depression); 2) these subgroups differ on outcomes (i.e., functional status, quality of life; 3) subgroup membership changes over time. Methods A secondary data analysis using data collected from 112 women at initial chemotherapy. Symptom and outcome measures were completed at three time points: baseline (i.e., the week before cycle two - T1); end of cancer treatment (T2), end of the study (approximately one year after the start of chemotherapy - T3). Cluster analysis identified patient subgroups based on symptom severity scores. Results At T1 and T2, four patient subgroups were identified: ALL LOW (one or no symptom greater than the cut score), MILD (two symptoms), MODERATE (three or four symptoms), and ALL HIGH (four symptoms). At T3, three subgroups were identified: MILD, MODERATE and ALL HIGH. Subgroups with high severity levels of all four symptoms had poorer functional status and QOL at each time point than other subgroups (p<.001). Group membership changed over time. Conclusions Subgroups of patients with different symptom experiences were identified. For some patients severity of all four symptoms persisted months after cancer treatment. Initial and ongoing assessment to identify those patients in the ALL HIGH patient subgroup is important so that appropriate interventions to improve functional status and quality of life can be offered.

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Research works printed but not linked: 4

  1. Bianco, 1991, Prognostic role of amenorrhea induced by adjuvant chemotherapy in premenopausal patients with early breast cancer, Br. J. Cancer, 63, 799, 10.1038/bjc.1991.177 · doi:10.1038/bjc.1991.177
  2. Hyde, 1973, Natural course of inoperable lung cancer, Chest, 64, 309, 10.1378/chest.64.3.309 · doi:10.1378/chest.64.3.309
  3. McQuitty, 1966, Similarity analysis of reciprocal pairs for discrete and continuous data, Edu. Psychol. Measure., 27, 21, 10.1177/001316446702700103 · doi:10.1177/001316446702700103
  4. Richards, 1990, Adjuvant cyclophosphamide, methotrexate, and fluorouracil in patients with axillary node-positive breast cancer: an update of the Guy's/Manchester trial, J. Clin. Oncol., 8, 2032, 10.1200/JCO.1990.8.12.2032 · doi:10.1200/jco.1990.8.12.2032

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Metadata

Authors
Dodd, M. J., Cho, M. H., Cooper, B. A., & Miaskowski, C.
Venue
European Journal of Oncology Nursing
Publisher
Elsevier BV
Published
2010-04
Volume
14
Issue
2
Pages
101-110
ISSN
1462-3889 (ISSN-L)
DOI
10.1016/j.ejon.2009.09.005
OpenAlex
W1973003045
Cited by
290
References
70
FWCI
6.41
Type
journal article
Language
en
Open access
bronze
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: The effect of symptom clusters on functional status and quality of life in women with breast cancer. https://app.cochat.ai/papers/10.1016/j.ejon.2009.09.005
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Dodd, M. J., Cho, M. H., Cooper, B. A., & Miaskowski, C. (2010). The effect of symptom clusters on functional status and quality of life in women with breast cancer. European Journal of Oncology Nursing. https://doi.org/10.1016/j.ejon.2009.09.005

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.