Cited by 198Musculoskeletal pain and rehabilitationPain Management and Placebo EffectPsychosomatic Disorders and Their Treatments

The role of depression and catastrophizing in musculoskeletal pain

Lintonl, Steven J., Nicholasl, Michael K., MacDonaldl, Shane, Boersmal, Katja, Bergboml, Sofia, Maherl, Chris, Refshaugel, Kathy·2011·European Journal of Pain

Abstract

Many patients with musculoskeletal pain also suffer from a depressed mood. Catastrophizing is one process that may link depression and pain since it is a key concept in models of both problems. Earlier research has suggested that catastrophizing measures something above and beyond depression. This study tests the idea that if depressed mood and catastrophizing are separate entities then when one is absent the other should still contribute to poor outcome, and, when both are present there should be an additional adverse effect. To this end, a prospective design, with a built‐in replication from two clinical samples of patients with sub‐acute pain (one from Sweden, N=373; one from Australasia, N=259), was employed. Participants were classified as to having high/low scores on measures of depression and catastrophizing. Subsequently, these classifications were studied in relation to outcome variables cross‐sectionally and at follow‐up. Results showed a small to moderate correlation between catastrophizing and depression and that there are individuals with one, but not the other problem. Further, having one or the other of the entities was associated with current pain problems and outcome, while having both increased the associations substantially. The replication showed very similar results Our data demonstrate that pain catastrophizing and heightened depressed mood have an additive and adverse effect on the impact of pain, relative to either alone. It suggests that each should be assessed in the clinic and that future research should focus on treatments specifically designed to tackle both depressed mood and catastrophizing.

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Crossref · 10.1016/j.ejpain.2010.08.009

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  • About 20% of people with chronic pain have depression, compared with less than 7% of the general population, and this pattern is found worldwide.

    “Approximately 20% of individuals with chronic pain also have depression, while less than 7% of the general population experiences this disorder, and these findings hold not just for the U.S. but around the world 231–235.”

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References 47 · Cited by 198

Authors
Lintonl, S. J., Nicholasl, M. K., MacDonaldl, S., Boersmal, K., Bergboml, S., Maherl, C., & Refshaugel, K.
Affiliations
  • Örebro University (SE)
  • The University of Sydney (AU)
Corresponding author
Lintonl, Steven J.
Venue
European Journal of Pain
Publisher
Wiley
Published
2011-04
Volume
15
Issue
4
Pages
416-422
ISSN
  • 1090-3801 (ISSN-L)
  • 1532-2149
OpenAlex
W1580122521
Cited by
198
References
47
Citations by year
2026: 4 · 2025: 8 · 2024: 12 · 2023: 13 · 2022: 20 · 2021: 12 · 2020: 20 · 2019: 13 · 2018: 16 · 2017: 10 · 2016: 16 · 2015: 10 · 2014: 12 · 2013: 12 · 2012: 10
FWCI
7.55
Type
journal article
Language
en
Open access
closed
Locations
  • European Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
pain catastrophizing, depression, depressive mood, musculoskeletal pain, pain-related disability, pain outcomes, replication
MeSH terms
Adult, Asia, Australia, Cross-Sectional Studies, Depression, Fear, Female, Follow-Up Studies, Humans, Longitudinal Studies, Male, Middle Aged, Musculoskeletal Diseases, Pain, Prospective Studies, Psychiatric Status Rating Scales, Risk Factors, Sweden, Odds Ratio, Treatment Outcome, Self Efficacy, Australasia, Catastrophization

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