The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.
Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles
Open accessAbstract
This paper reviews the major factors that are closely involved in peptide and protein degradation during the preparation of biodegradable nano- and microparticles. The various means usually employed for overcoming these obstacles are described, in order to bring to the fore the strategies for protein stabilization. Both processing and formulation parameters can be modified and are distinctly considered from a strategic point of view. We describe how partial or full protein stability retention within the carriers and during drug release might be achieved by individual or combined optimized strategies. Additionally, problems commonly encountered during protein quantification, stability determination and release are briefly reviewed. Artefacts that might occur during sampling and analytical procedures and which might hinder critical interpretation of results are discussed.
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Cites
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Cyclodextrin based novel drug delivery systems
Vyas, A., Saraf, S., & Saraf, S. (2008) · Journal of Inclusion Phenomena and Macrocyclic Chemistry · doi:10.1007/s10847-008-9456-y · Cited by 412
Effective GDNF brain delivery using microspheres—A promising strategy for Parkinson's disease
Garbayo, E., Montero-Menei, C. N., Ansorena, E., Lanciego, J. L., Aymerich, M. S., & Blanco-Prieto, M. J. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.12.010 · Cited by 150
Salman, A., Kantor, A., McClements, M. E., Marfany, G., Trigueros, S., & MacLaren, R. E. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14091842 · Cited by 37
Bhujel, R., Maharjan, R., Kim, N. A., & Jeong, S. H. (2021) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2021.102608 · Cited by 26
Biodegradable microparticles for strictly regulating the release of neurotrophic factors
Gujral, C., Minagawa, Y., Fujimoto, K., Kitano, H., & Nakaji-Hirabayashi, T. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.03.031 · Cited by 21
Metadata
- Authors
- Bilati, U., Allémann, E., & Doelker, E.
- Venue
- European Journal of Pharmaceutics and Biopharmaceutics
- Publisher
- Elsevier BV
- Published
- 2005-04
- Volume
- 59
- Issue
- 3
- Pages
- 375-388
- ISSN
- 0939-6411 (ISSN-L)
- OpenAlex
- W2071521950
- Cited by
- 313
- References
- 91
- FWCI
- 7.60
- Type
- journal article
- Language
- en
- Open access
- green
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- Bilati, U., Allémann, E., & Doelker, E. (2005). Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles. European Journal of Pharmaceutics and Biopharmaceutics. https://doi.org/10.1016/j.ejpb.2004.10.006
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
