Cited by 310Heavy Metal Exposure and ToxicityHeavy metals in environmentEnvironmental Toxicology and Ecotoxicology

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Exposure to metal mixtures and human health impacts in a contaminated area in Nanning, China

Open access
Cui, Yujing, Zhu, Yong-Guan, Zhai, Rihong, Huang, Yizhong, Qiu, Yi, Liang, Jianzhong·2005·Environment International

Abstract

Cadmium and lead have been identified as very toxic metals, which are widely present in the environment due to natural and anthropogenic emissions. Many studies have shown that the food chain is the main pathway of cadmium and lead transfer from the environment to humans. It is well documented that many factors will affect their transfer through food chains. Previous investigations on heavy metals were mostly concentrated on one contaminant in isolation. However, in real environments, exposure to mixtures of metals is ubiquitous such that cadmium pollution is invariably being associated with lead and zinc, etc. This study focuses on the contamination and health effects of the metal mixtures. For this purpose, a dietary survey was taken for 3 groups in Nanning in October 2002. Samples of soils, plants (vegetables), urine and blood of humans were measured for Cd, Fe, Cu, Zn, Ca and Pb, in addition, the urinary indicators of renal dysfunction Albumin (ALB), N-acetyl-beta-D-glucosaminidase (NAG), Beta-2-microglobulin (beta2-MG) and Retinol-binding protein (RBP) in urine were also measured. Results showed that soil contamination with metal mixtures had caused significant renal dysfunction of the local residents living in the contaminated area, and the dose-response curve was somewhat altered by the mixed contamination of Cd and Pb as well as the intake of other minerals. The importance of mixtures of metal contamination and human health are also discussed in this paper.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.envint.2005.05.025

Cites

26 of 26 references verified0 citation errors · 0 not checkable

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  • Potentially toxic elements in soils can transfer to other environmental compartments, such as aquatic ecosystems, through erosion and surface runoff from agricultural land.

    “Moreover, PTEs in soils can transfer to other environmental compartments, such as aquatic ecosystems, through erosion and surface runoff from agricultural land (Cui et al., 2005;Luo et al., 2007).”

Citations

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Research works printed but not linked: 5

  1. Cai, 1998, Cadmium and renal dysfunction: dose response in a population living in an area contaminated by irrigation water, WHO Bull, 76, 153
  2. Chen, 2002, The method of analysis of essential elements in soil and sewage sludge with ICP-MS (1), Environ Chem, 21, 509
  3. Järup, 1998, Health effect of cadmium exposure—a review of the literature and risk estimate, Scand J Work Environ Health, 24, 1
  4. Nordberg, 1996, Current issues in low-dose cadmium toxicology: nephrotoxicity and carcinogenicity, Environ Sci, 4, 133
  5. WHO, 1992, Cadmium, Vol. 134

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Metadata

Authors
Cui, Y., Zhu, Y.-G., Zhai, R., Huang, Y., Qiu, Y., & Liang, J.
Affiliations
Chinese Academy of Sciences (CN)
Corresponding author
Zhu, Yong-Guan
Venue
Environment International
Publisher
Elsevier BV
Published
2005-08
Volume
31
Issue
6
Pages
784-790
ISSN
0160-4120 (ISSN-L)
OpenAlex
W2096436844
Cited by
310
References
26
Citations by year
2026: 5 · 2025: 5 · 2024: 12 · 2023: 13 · 2022: 21 · 2021: 17 · 2020: 16 · 2019: 15 · 2018: 17 · 2017: 16 · 2016: 23 · 2015: 24 · 2014: 21 · 2013: 17 · 2012: 16
FWCI
6.72
Type
journal article
Language
en
Open access
Locations
  • Environment International (publishedVersion)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Research Center for Eco-Environmental Sciences OpenIR (Chinese Academy of Sciences) (submittedVersion, cc-by-nc-nd)
Funders
Natural Science Foundation of Guangxi Province
Topics
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
  • Physical Sciences › Environmental Science › Pollution › Heavy metals in environment
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
Keywords
metal mixtures, cadmium, lead, soil contamination, dietary exposure, renal dysfunction, urinary biomarkers, N-acetyl-beta-D-glucosaminidase, beta2-microglobulin, retinol-binding protein, albumin, dose-response relationship, zinc, Nanning
MeSH terms
Acetylglucosaminidase, Albumins, beta 2-Microglobulin, China, Environmental Monitoring, Female, Food Contamination, Humans, Kidney, Male, Retinol-Binding Proteins, Soil Pollutants, Vegetables, Metals, Heavy

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