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Cited by 103

The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.

Associations of long-term exposure to air pollution and road traffic noise with cognitive function—An analysis of effect measure modification

Tzivian, Lilian, Jokisch, Martha, Winkler, Angela, Weimar, Christian, Hennig, Frauke, Sugiri, Dorothea, Soppa, Vanessa J., Dragano, Nico, Erbel, Raimund, Jöckel, Karl-Heinz, Moebus, Susanne, Hoffmann, Barbara·2017·Environment International
DOI 10.1016/j.envint.2017.03.018
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Abstract

Background Adverse effects of traffic-related air pollution (AP) and noise on cognitive functions have been proposed, but little is known about their interactions and the combined effect of co-exposure. Methods Cognitive assessment was completed by 4086 participants of the population-based Heinz Nixdorf Recall cohort study using five neuropsychological subtests and an additively calculated global cognitive score (GCS). We assessed long-term residential concentrations for size-fractioned particulate matter (PM) and nitrogen oxides with land use regression. Road traffic noise (weighted 24-h (L DEN ) and night-time (L NIGHT ) means) was assessed according to the EU directive 2002/49/EC. Linear regression models adjusted for individual-level characteristics were calculated to estimate effect modification of associations between AP and noise with cognitive function. We used multiplicative interaction terms and categories of single or double high exposure, dichotomizing the potential effect modifier at the median (AP) or at an a priori defined threshold (road traffic noise). Results In fully adjusted models, high noise exposure increased the association of AP with cognitive function. For example, for an interquartile range increase of PM 2.5 (IQR 1.43), association s with GCS were: estimate (β)=-0.16 [95% confidence interval: -0.33; 0.01] and β=-0.48 [-0.72; -0.23] for low and high L DEN , respectively. The association of noise with GCS was restricted to highly AP-exposed participa…

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  1. European Commission, 2002, Directive 2002/49/EC of the European Parliament and of the Council of 25 June 2002 relating to the assessment and management of environmental noise, Off. J. Eur. Union

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Metadata

Authors
Tzivian, L., Jokisch, M., Winkler, A., Weimar, C., Hennig, F., Sugiri, D., Soppa, V. J., Dragano, N., Erbel, R., Jöckel, K.-H., Moebus, S., & Hoffmann, B.
Venue
Environment International
Publisher
Elsevier BV
Published
2017-06
Volume
103
Pages
30-38
ISSN
0160-4120
DOI
10.1016/j.envint.2017.03.018
Cited by
103
References
61
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
  • German Ministry of Education and Science
  • German Research Council (3314/2-3, 3314/4-3, 155/6-2, 236/10-1)

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