Critical analytical evaluation of promising markers for sarcopenia

Sarcopenia: European consensus on definition and diagnosis

Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., Martin, F. C., Michel, J.-P., Rolland, Y., Schneider, S. M., et al. (2010) · Age and Ageing · doi:10.1093/ageing/afq034 · Cited by 11,601 · see citing works

Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

Schuelke, M., Wagner, K. R., Stolz, L. E., Hübner, C., Riebel, T., Kömen, W., Braun, T., Tobin, J. F., & Lee, S.-J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040933 · Cited by 1,399 · see citing works

Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity--correlation with body mass index.

Stengel, A., Hofmann, T., Goebel-Stengel, M., Elbelt, U., Kobelt, P., & Klapp, B. (2013) · Peptides · doi:10.1016/j.peptides.2012.11.014 · Cited by 439 · see citing works

An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy

Lach-Trifilieff, E., Minetti, G. C., Sheppard, K., Ibebunjo, C., Feige, J. N., Hartmann, S., Brachat, S., Rivet, H., Koelbing, C., Morvan, F., et al. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.01307-13 · Cited by 306 · see citing works

Regulation of Muscle Mass by Follistatin and Activins

Lee, S.-J., Lee, Y.-S., Zimmers, T. A., Soleimani, A., Matzuk, M. M., Tsuchida, K., Cohn, R. D., & Barton, E. R. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0127 · Cited by 273 · see citing works

Irisin and exercise training in humans – Results from a randomized controlled training trial

Hecksteden, A., Wegmann, M., Steffen, A., Kraushaar, J., Morsch, A., Ruppenthal, S., Kaestner, L., & Meyer, T. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-235 · Cited by 250 · see citing works

Tools in the Assessment of Sarcopenia

Cooper, C. C., Fielding, R. A., Visser, M., van Loon, L. J. C., Rolland, Y., ORWOLL, E. S., Reid, K. F., Boonen, S., Dere, W. H., Epstein, S., et al. (2013) · Calcified Tissue International · doi:10.1007/s00223-013-9757-z · Cited by 246 · see citing works

Interactions Between Muscle Tissues and Bone Metabolism

Kawao, N., & Kaji, H. (2014) · Journal of Cellular Biochemistry · doi:10.1002/jcb.25040 · Cited by 231 · see citing works

Myostatin (GDF-8) as a key factor linking muscle mass and bone structure.

Elkasrawy, M., & Hamrick, M. W. (2010) · PubMed · Cited by 203 · see citing works

Interaction between Muscle and Bone

Kaji, H. (2014) · Journal of Bone Metabolism · doi:10.11005/jbm.2014.21.1.29 · Cited by 199 · see citing works

Estimation of sarcopenia prevalence using various assessment tools

Beaudart, C., Reginster, J., Slomian, J., Buckinx, F., Dardenne, N., Quabron, A., Slangen, C., Gillain, S., Pétermans, J., & Bruyère, O. (2014) · Experimental Gerontology · doi:10.1016/j.exger.2014.11.014 · Cited by 153 · see citing works

Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child

Čatipović, B. (2004) · New England Journal of Medicine · doi:10.1056/nejm200409023511018 · Cited by 131 · see citing works

Prevalence of sarcopenia: the impact of different diagnostic cut-off limits.

Beaudart, C., Reginster, J.-Y., Slomian, J., Buckinx, F., Locquet, M., & Bruyère, O. (2014) · PubMed · Cited by 87 · see citing works

Inconsistency in Circulating Irisin Levels: What is Really Happening?

Sanchis‐Gomar, F., Alis, R., Pareja-Galeano, H., Romagnoli, M., & Pérez-Quilis, C. (2014) · Hormone and Metabolic Research · doi:10.1055/s-0033-1363283 · Cited by 58 · see citing works

PROCOLLAGEN TYPE III N-TERMINAL PEPTIDE (P3NP) AND LEAN MASS: A CROSS-SECTIONAL STUDY

Berry, S. D., Vasan, R. S., Cawthon, P. M., Gona, P. N., McLean, R. R., Cupples, L. A., & Kiel, D. P. (2013) · The Journal of Frailty & Aging · doi:10.14283/jfa.2013.19 · Cited by 28 · see citing works

Sarcopenia in daily practice: assessment and management

Beaudart, C., McCloskey, E. V., Bruyère, O., Cesari, M., Rolland, Y., Rizzoli, R., de Carvalho, I. A., Thiyagarajan, J. A., Bautmans, I., Bertiére, M.-C., et al. (2016) · BMC Geriatrics · doi:10.1186/s12877-016-0349-4 · Cited by 855 · see citing works

Myostatin and muscle atrophy during chronic kidney disease

Bataille, S., Chauveau, P., Fouque, D. P., Aparicio, M., & Koppe, L. (2020) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfaa129 · Cited by 97 · see citing works

Doxycycline host-directed therapy in human pulmonary tuberculosis

Miow, Q. H., Vallejo, A. F., Wang, Y., Hóng, J., Bai, C. G., Teo, F. S. W., Wang, D. A., Loh, H. R., Tan, T. Z., Ding, Y., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci141895 · Cited by 86 · see citing works

Biochemical Markers of Musculoskeletal Health and Aging to be Assessed in Clinical Trials of Drugs Aiming at the Treatment of Sarcopenia: Consensus Paper from an Expert Group Meeting Organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the Centre Académique de Recherche et d'Expérimentation en Santé (CARES SPRL), Under the Auspices of the World Health Organization Collaborating Center for the Epidemiology of Musculoskeletal Conditions and Aging

Ladang, A., Beaudart, C., Reginster, J., Al‐Daghri, N. M., Bruyère, O., Burlet, N., Cesari, M., Cherubini, A., da Silva, M. C., Cooper, C. C., et al. (2023) · Calcified Tissue International · doi:10.1007/s00223-022-01054-z · Cited by 82 · see citing works

Myostatin and Insulin-Like Growth Factor 1 Are Biomarkers of Muscle Strength, Muscle Mass, and Mortality in Patients on Hemodialysis

Delanaye, P., Bataille, S., Quinonez, K., Buckinx, F., Warling, X., Krzesinski, J.-M., Pottel, H., Burtey, S., Bruyère, O., & Cavalier, E. (2019) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2018.11.010 · Cited by 54 · see citing works

A Phase 1 study for safety and pharmacokinetics of BIO101 (20‐hydroxyecdysone) in healthy young and older adults

Dioh, W., Tourette, C., Del Signore, S., Daudigny, L., Dupont, P., Balducci, C., Dilda, P. J., Lafont, R., & Veillet, S. (2023) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.13195 · Cited by 40 · see citing works

Sarcopenia, the last organ insufficiency

Cruz-Jentoft, A. J. (2016) · European Geriatric Medicine · doi:10.1016/j.eurger.2016.01.003 · Cited by 32 · see citing works

Serum creatinine and cystatin C-based index can be a screening biomarker for sarcopenia in older population

Singhal, S., Singh, S., Upadhyay, A. D., Dwivedi, S. N., Das, C. J., Mohta, S., Chatterjee, P., Dey, A. B., & Chakrawarty, A. (2019) · European Geriatric Medicine · doi:10.1007/s41999-019-00197-x · Cited by 24 · see citing works

A Sensitive and Selective Immunoassay for the Quantitation of Serum Latent Myostatin after In Vivo Administration of SRK-015, a Selective Inhibitor of Myostatin Activation

Cote, S. M., Jackson, J., Pirruccello, M., Carven, G. J., & Wawersik, S. (2019) · SLAS DISCOVERY · doi:10.1177/2472555219860779 · Cited by 6 · see citing works

Combination of Clinical Frailty Score and Myostatin Concentrations as Mortality Predictor in Hemodialysis Patients

Cornet, S., Quinonez, K., Warling, X., Jouret, F., Lanot, A., Bruyère, O., Cavalier, E., & Delanaye, P. (2025) · Journal of Renal Nutrition · doi:10.1053/j.jrn.2025.01.005 · Cited by 3 · see citing works

Serum Growth Differentiation Factor 8 (Myostatin) Concentrations in Cats with Early-Stage Chronic Kidney Disease

Fleming, K., & Whitehouse, W. H. (2026) · Veterinary Sciences · doi:10.3390/vetsci13010089

Impact de l'insuffisance rénale sur l'accumulation de myostatine et la régénération musculaire : rôle de l'indoxyl sulfate

Bataille, S. (2021) · doi:10.70675/40436641zf097z4c9ez91aaz1f0d4d395911

The novel myokine irisin: clinical implications and potential role as a biomarker for sarcopenia in postmenopausal women

Park, H., Kim, H. C., Zhang, D., Yeom, H., & Lim, S.-K. (2018) · Endocrine · doi:10.1007/s12020-018-1814-y · Cited by 112 · see citing works

Circulating irisin levels as a predictive biomarker for sarcopenia: a cross-sectional community-based study

Chang, J. S., Kim, T. H., Nguyen, T. T., Park, K., Kim, N., & Kong, I. D. (2017) · Geriatrics & Gerontology International · doi:10.1111/ggi.13030 · Cited by 166 · see citing works

Circulating irisin levels in patients with sarcopenia: a systematic review and meta-analysis

Zhang, L., Peng, Y., Kong, Y., Zhang, X., Li, Z., & Jia, H. (2024) · European Geriatric Medicine · doi:10.1007/s41999-024-01097-5 · Cited by 17 · see citing works

Evaluation of the intra-individual variability of myostatin and activin A, two biomarkers of sarcopenia. Impact of the least significant change and follow-up of the patients

Cavalier, E., Piron, C., Watar, F., Kovacs, S., Beaudart, C., Buckinx, F., Bruyère, O., Goff, C. M. L., & Reginster, J. (2016) · Open Repository and Bibliography (University of Liège)

Study of irisin as a biomarker and thigh muscle ultrasound as a screening tool for sarcopenia among a cohort of older people

Sabagh, N. M. E., Soliman, E. A. E., Imbaby, S. A. E., Khalifa, M. S. A. E., & Salamah, A. (2025) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.4103/ajom.ajom_14_25