Order and disorder in the transparent media of the eye
Abstract
Transparent tissues of the eye share common physical features that were important to the scientific studies of Dr David Maurice. The importance of order and disorder in the structural organization of the collagen fibres and crystallin proteins of the lens is discussed briefly in the present article. Dr Maurice emphasized the use of mathematical models in the investigation of biological phenomena in vision and his research continues to inspire novel experimental investigations of the transparent and opaque of the eye.
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If the endothelial pumping mechanism fails and the cornea swells, regions devoid of collagen fibrils (lakes) impair corneal transparency.
“If this mechanism fails and the cornea swells, regions devoid of collagen fibrils (termed lakes) impair corneal transparency (Clark, 2004, Meek et al., 2003).”
From Corneal structure and transparency (2015) · cites this paper as Clark, 2004
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Corneal structure and transparency
Meek, K. M., & Knupp, C. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.07.001 · Cited by 853 · see citing works
- Authors
- Clark, J. I.
- Affiliations
- University of Washington (US)
- Corresponding author
- Clark, John I.
- ORCID
- Clark, John I.
- Venue
- Experimental Eye Research
- Publisher
- Elsevier BV
- Published
- 2004-03
- Volume
- 78
- Issue
- 3
- Pages
- 427-432
- ISSN
- 0014-4835 (ISSN-L)
- OpenAlex
- W1977494365
- Cited by
- 36
- References
- 0
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 3 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 2 · 2012: 2
- FWCI
- 4.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Experimental Eye Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Eye Institute (R01EY013180, EY 04542, R01EY004542, EY13180)
- Topics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › History of Science and Medicine
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Corneal surgery and disorders
- Keywords
- collagen fibers, crystallins, lens structure
- MeSH terms
- Cataract, Collagen, Cornea, Corneal Diseases, Crystallins, Humans, Lens, Crystalline, Scattering, Radiation
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