Neuroinflammation in glaucoma: A new opportunity

Williams, Pete A., Marsh-Armstrong, Nick, Howell, Gareth R., Bosco, Alejandra, Danias, John, Simon, John, Di Polo, Adriana, Kuehn, Markus H. +3 more·2017·Experimental Eye Research

DOI 10.1016/j.exer.2017.02.014

Cited by (252)

Items 101–200 of 252

Global and Regional Damages in Retinal Ganglion Cell Axon Bundles Monitored Non-Invasively by Visible-Light Optical Coherence Tomography Fibergraphy
Marta Grannonico, David A. Miller, Mingna Liu, Pedro Norat, Christopher D. Deppmann, Peter A. Netland, Hao F. Zhang, Xiaorong Liu · 2021 · Journal of Neuroscience
Proteome alterations in the aqueous humor reflect structural and functional phenotypes in patients with advanced normal-tension glaucoma
Si Hyung Lee, Jae Hun Jung, Tae Kwann Park, Chae‐Eun Moon, Kyusun Han, Jinhyoung Lee, Hyung Keun Lee, Yong Woo Ji, Chan Yun Kim · 2022 · Scientific Reports
Apoptosis in glaucoma: A new direction for the treatment of glaucoma (Review)
Qiongrong Xia, Dingding Zhang · 2024 · Molecular Medicine Reports
Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway
Shangli Ji, Jie Xiao, Jian Liu, Shibo Tang · 2019 · Stem Cells International
Magnesium acetyltaurate protects against endothelin-1 induced RGC loss by reducing neuroinflammation in Sprague dawley rats
Natasha Najwa Nor Arfuzir, Renu Agarwal, Igor Nikolayevich Iezhitsa, Puneet Agarwal, Nafeeza Mohd Ismail · 2020 · Experimental Eye Research
The correlation between primary open-angle glaucoma (POAG) and gut microbiota: a pilot study towards predictive, preventive, and personalized medicine
Si Chen, Nan Wang, Siqi Xiong, Xiaobo Xia · 2023 · The EPMA Journal
Glaucoma Patients Have a Lower Abundance of Butyrate-Producing Taxa in the Gut
Joëlle E. Vergroesen, Zakariya A. Jarrar, Stefan Weiß, Fabian Frost, Abdus Samad Ansari, Picard Nguyen, Robert Kraaij, Carolina Medina‐Gómez, Henry Völzke, Frank Tost et al. · 2024 · Investigative Ophthalmology & Visual Science
Neuroprotection of Retinal Ganglion Cells Suppresses Microglia Activation in a Mouse Model of Glaucoma
Sandeep Kumar, Abram Akopian, Stewart A. Bloomfield · 2023 · Investigative Ophthalmology & Visual Science
Inhibition of NOX4 with GLX351322 alleviates acute ocular hypertension-induced retinal inflammation and injury by suppressing ROS mediated redox-sensitive factors activation
Jing Liao, Biyan Peng, Guangyi Huang, Chunli Diao, Yuanjun Qin, Yiyi Hong, Jiali Lin, Yunru Lin, Li Jiang, Ningning Tang et al. · 2023 · Biomedicine & Pharmacotherapy
CD200Fc Attenuates Retinal Glial Responses and RGCs Apoptosis After Optic Nerve Crush by Modulating CD200/CD200R1 Interaction
R. Stephanie Huang, Qianqian Lan, Lifei Chen, Haibin Zhong, Ling Cui, Li Jiang, Hui Huang, Li Li, Siming Zeng, Min Li et al. · 2017 · Journal of Molecular Neuroscience
The role of neuroinflammation in the pathogenesis of glaucoma neurodegeneration
Maria Dolores Pinazo-Duran, Francisco José Muñoz-Negrete, Silvia Maria Sanz-Gonzalez, Javier Benítez del Castillo Sánchez, R. Giménez-Gómez, Mar Valero-Velló, Vicente Zanón‐Moreno, José Javier García‐Medina · 2020 · Progress in brain research
Lipid mediators in glaucoma: Unraveling their diverse roles and untapped therapeutic potential
DJ Mathew, Jeremy M. Sivak · 2024 · Prostaglandins & Other Lipid Mediators
MicroRNA ‐146a‐5p protects retinal ganglion cells through reducing neuroinflammation in experimental glaucoma
Han Zhou, Rui‐Kang Yang, Qian Li, Zhen Li, Yongchen Wang, Shuying Li, Yanying Miao, Xinghuai Sun, Zhongfeng Wang · 2024 · Glia
Clinical Significance of Albumin‐ and Bilirubin‐Based Biomarkers in Glaucoma: A Retrospective Case‐Control Study
Chong He, Gao Zhang, Jing Fu, Rui Zhang, An Li, Donghua Liu, Binghong Li, Chen Yang, Bolin Deng, Yilian Chen et al. · 2022 · Oxidative Medicine and Cellular Longevity
Targeting Differential Roles of Tumor Necrosis Factor Receptors as a Therapeutic Strategy for Glaucoma
Lidawani Lambuk, Suhana Ahmad, Muhammad Zulfiqah Sadikan, Nor Asyikin Nordin, Ramlah Kadir, Nurul Alimah Abdul Nasir, Xin Chen, Jennifer C. Boer, Magdalena Plebanski, Rohimah Mohamud · 2022 · Frontiers in Immunology
Astrocytes of the optic nerve exhibit a region-specific and temporally distinct response to elevated intraocular pressure
Arpan G. Mazumder, Amélie M. Julé, Daniel Sun · 2023 · Molecular Neurodegeneration
A Novel Synthetic Steroid of 2β,3α,5α-Trihydroxy-androst-6-one Alleviates the Loss of Rat Retinal Ganglion Cells Caused by Acute Intraocular Hypertension via Inhibiting the Inflammatory Activation of Microglia
Hongjiaqi Sun, Dongdong Xue, Bingzheng Lu, Yuan Li, Longxiang Sheng, Zhu Zhu, Yu-Wei Zhou, Jingxia Zhang, Gan-Jian Lin, Suizhen Lin et al. · 2019 · Molecules
Erythropoietin attenuates motor neuron programmed cell death in a burn animal model
Sheng‐Hua Wu, I‐Cheng Lu, Su‐Shin Lee, Aij‐Lie Kwan, Chee‐Yin Chai, Shu‐Hung Huang · 2018 · PLoS ONE
Progressive retinal nerve fibre layer thinning and choroidal microvasculature dropout at the location of disc haemorrhage in glaucoma
Chung Young Kim, Eun Ji Lee, Ji‐Ah Kim, Hyunjoong Kim, Tae‐Woo Kim · 2020 · British Journal of Ophthalmology
Alterations in Peripheral B Cell Subsets Correlate with the Disease Severity of Human Glaucoma
Ling Yu, Yang Chen, Xiang Ming Xu, Qiwei Dong, Wenbo Xiu, Qinyuan Chen, Jinxia Wang, Chong He, Jian Ye, Fang Lu · 2021 · Journal of Inflammation Research
Microstructure and resident cell-types of the feline optic nerve head resemble that of humans
Kazuya Oikawa, Leandro B. C. Teixeira, Adib Keikhosravi, Kevin W. Eliceiri, Gillian J. McLellan · 2020 · Experimental Eye Research
Priming and release of cytokine IL-1β in microglial cells from the retina
Keith E. Campagno, Wennan Lu, Puttipong Sripinun, Farraj Albalawi, Aurora Cenaj, Claire H. Mitchell · 2025 · Experimental Eye Research
Glial and immune dysregulation in glaucoma independent of retinal ganglion cell loss: a human post-mortem histopathology study
Akanksha Salkar, Viswanthram Palanivel, Devaraj K. Basavarajappa, Mehdi Mirzaei, Angela Schulz, Peng Yan, Vivek Gupta, Stuart L. Graham, Yuyi You · 2025 · Acta Neuropathologica Communications
Mechanobiology in the eye
C. Ross Ethier, Samuel Herberg · 2025 · npj Biological Physics and Mechanics.
Inflammatory Mediators of Axon Regeneration in the Central and Peripheral Nervous Systems
Larry I. Benowitz, Lili Xie, Yuqin Yin · 2023 · International Journal of Molecular Sciences
The Future of Stem Cells and Their Derivates in the Treatment of Glaucoma. A Critical Point of View
S Nicoară, Ioana Carmen Brie, Ancuta Maria Jurj, Olga Şoriţău · 2021 · International Journal of Molecular Sciences
Inhibition of the cysteinyl leukotriene pathways increases survival of RGCs and reduces microglial activation in ocular hypertension
Andrea Trost, Karolina A. Motloch, Andreas Koller, Daniela Bruckner, Christian Runge, Falk Schroedl, Barbara Bogner, Alexandra Kaser-Eichberger, Clemens Strohmaier, Anja‐Maria Ladek et al. · 2021 · Experimental Eye Research
Ocular microbial diversity, community structure, and function at high altitude
Zhouyu Li, Yongguo Xiang, Yong Wang, Wenjuan Wan, Zi Ye, Shijie Zheng, Yanyi Chen, Liang Xiong, Lu Zhu, Yan Ji et al. · 2021 · Microbial Pathogenesis
Increased Hydrostatic Pressure Promotes Primary M1 Reaction and Secondary M2 Polarization in Macrophages
Bo Wang, Maren Kasper, Björn Laffer, Gerd Meyer zu Hörste, Susanne Wasmuth, Martin Busch, Tida Viola Jalilvand, Solon Thanos, Arnd Heiligenhaus, Dirk Bauer et al. · 2020 · Frontiers in Immunology
The prophylactic value of TNF ‐α inhibitors against retinal cell apoptosis and optic nerve axon loss after corneal surgery or trauma
Eleftherios I. Paschalis, Chengxin Zhou, Jyoti Kumar Sharma, Thomas H. Dohlman, Sarah Y. Kim, Fengyang Lei, James Chodosh, Demetrios G. Vavvas, Arto O. Urtti, George N. Papaliodis et al. · 2023 · Acta Ophthalmologica
Immunological and molecular basics of the primary open angle glaucoma pathomechanism
Katarzyna Samelska, Anna Zaleska-Żmijewska, Barbara Joanna Bałan, Andrzej Grąbczewski, Jacek Paweł Szaflik, Aleksander Jan Kubiak, Piotr Skopiński · 2021 · Central European Journal of Immunology
Comparative lipidomic analysis of inflammatory mediators in the aqueous humor and tear fluid of humans and rabbits
Dmitry V. Chistyakov, Nadezhda V. Azbukina, Alina A. Astakhova, Sergei V. Goriainov, V. V. Chistyakov, Veronika V. Tiulina, Viktoriia E. Baksheeva, Vladislav I. Kotelin, Elena V. Fedoseeva, Andrey A. Zamyatnin et al. · 2020 · Metabolomics
Myeloid masquerade: Microglial transcriptional signatures in retinal development and disease
Kristen M. Pitts, Milica A. Margeta · 2023 · Frontiers in Cellular Neuroscience
Roflumilast attenuates neuroinflammation post retinal ischemia/reperfusion injury by regulating microglia phenotype via the Nrf2/STING/NF-κB pathway
Yuyan Guo, Chunlian Ou, Naiyuan Zhang, Qiong Liu, Ke Xiong, Jian Yu, Hao Cheng, Linjiang Chen, Ming Ma, Jing Xu et al. · 2023 · International Immunopharmacology
Glaucoma and the Human Microbiome
Chih-Chiun Jamie Chang, Benjamin Liu, Jeffrey M. Liebmann, George A. Cioffi, Bryan J. Winn · 2024 · Journal of Glaucoma
Engineered bio-functional material-based nerve guide conduits for optic nerve regeneration: a view from the cellular perspective, challenges and the future outlook
Enoch Obeng, Baoguo Shen, Wei Wang, Zhenyuan Xie, Wenyi Zhang, Zhixing Li, Qinqin Yao, Wencan Wu · 2024 · Regenerative Biomaterials
Interaction of Wip1 and NF-κB regulates neuroinflammatory response in astrocytes
Fan Xu, Lifei Chen, Xin Zhao, Haibin Zhong, Ling Cui, Li Jiang, Hui Huang, Li Li, Siming Zeng, Min Li · 2017 · Inflammation Research
Nonsteroidal anti-inflammatory drugs for retinal neurodegenerative diseases
Chen Chen, Chenguang Wang, Xuebin Zhou, Lingxian Xu, Han Chen, Kun Qian, Bo Jia, Guanfang Su, Jinling Fu · 2021 · Prostaglandins & Other Lipid Mediators
Association between serum interleukin-6 levels with the risk and clinical severity of primary open-angle glaucoma
Z. S. Ulhaq, Yuliono Trika Nur Hasan, L. N. Rachma, G. Soraya · 2021 · Expert Review of Ophthalmology
A Robust Microbead Occlusion Model of Glaucoma for the Common Marmoset
Sandeep Kumar, Alexandra Benavente-Pérez, Reynolds Kwame Ablordeppey, Carol Ren Lin, Suresh Viswanáthan, Abram Akopian, Stewart A. Bloomfield · 2022 · Translational Vision Science & Technology
Protective effects of blocking PD-1 pathway on retinal ganglion cells in a mouse model of chronic ocular hypertension
Siqi Sheng, Yixian Ma, Yue Xian Zou, Fangyuan Hu, Ling Chen · 2023 · Frontiers in Immunology
The TβR II-targeted aptamer S58 prevents fibrosis after glaucoma filtration surgery
Xueru Li, Yu Leng, Xiangji Li, Yawei Wang, Peng Luo, Chi Zhang, Ziwen Wang, Xiaofeng Yue, Chongxing Shen, Long Chen et al. · 2020 · Aging
The association of toll-like receptor 4 gene polymorphisms with primary open angle glaucoma susceptibility: a meta-analysis
Narttaya Chaiwiang, Teera Poyomtip · 2019 · Bioscience Reports
Reduction of Neuroinflammation by δ-Opioids Via STAT3-Dependent Pathway in Chronic Glaucoma Model
Shahid Husain, Syed Adeel H. Zaidi, Sudha Singh, Wendy Guzman, Shikhar Mehrotra · 2021 · Frontiers in Pharmacology
Evaluation of the Effectiveness of a Chronic Ocular Hypertension Mouse Model Induced by Intracameral Injection of Cross-Linking Hydrogel
Junjue Chen, Jun You Sun, Huan Yu, Ping Cheong Huang, Yisheng Zhong · 2021 · Frontiers in Medicine
Lithium and Atypical Antipsychotics: The Possible WNT/β Pathway Target in Glaucoma
Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier · 2021 · Biomedicines
Anti-inflammatory Effects of GTE in Eye Diseases
Jian Li, Lin Du, Jing Na He, Kai On Chu, Cosmos Liutao Guo, Mandy Oi Man Wong, Chi Pui Pang, Wai Kit Chu · 2021 · Frontiers in Nutrition
COG1410 regulates microglial states and protects retinal ganglion cells in retinal ischemia-reperfusion injury
Ru Zhao, Tao He, Yiqiao Xing, Jinyuan Luo · 2023 · Experimental Eye Research
Glial-mediated immune modulation in glaucomatous neurodegeneration: mechanisms and therapeutic implications
Fangwei Zong, Jiaxin You, Hong Wu, Xuerui Wang · 2025 · Frontiers in Immunology
Systemic Treatment with Pioglitazone Reverses Vision Loss in Preclinical Glaucoma Models
Huilan Zeng, Alina V. Dumitrescu, David Wadkins, Benjamin W. Elwood, Oliver W. Gramlich, Markus H. Kuehn · 2022 · Biomolecules
Optic Nerve Head Myelin-Related Protein, GFAP, and Iba1 Alterations in Non-Human Primates With Early to Moderate Experimental Glaucoma
Priya Chaudhary, Cheri Stowell, Juan F. Reynaud, Stuart K. Gardiner, Hongli Yang, Galen A. Williams, Imee Williams, Nicholas Marsh‐Armstrong, Claude F. Burgoyne · 2022 · Investigative Ophthalmology & Visual Science
Oxidized low-density lipoprotein changes the inflammatory status and metabolomics profiles in human and mouse macrophages and microglia
Yaru Sun, Jiajian Liang, Jianming Xu, Kewen Zhou, Changzhen Fu, Shao-Lang Chen, Rucui Yang, Tsz Kin Ng, Qingping Liu, Mingzhi Zhang · 2024 · Heliyon
Understanding glaucoma as astrocyte-driven neurodegeneration in the optic nerve head: an integrative clinicopathological perspective
Eun Jung Lee, Do Young Park, Jong Chul Han, Changwon Kee · 2025 · Progress in Retinal and Eye Research
Oxymatrine Protects TGFβ1-Induced Retinal Fibrosis in an Animal Model of Glaucoma
Ashmita Das, Onkar Kashyap, Amrita Singh, Jaya Shree, Kamta Prashad Namdeo, Surendra Haribhau Bodakhe · 2022 · Frontiers in Medicine
Degeneration of retina-brain components and connections in glaucoma: Disease causation and treatment options for eyesight preservation
Najam A. Sharif · 2022 · Current Research in Neurobiology
Risk of cancer in patients with glaucoma: A nationwide population-based cohort study
Younhea Jung, Kyungdo Han, Kyung‐Sun Na, Gee-Hyun Kim, Minji Ha, Jisun Paik, Jung Il Moon · 2020 · Scientific Reports
Ribonuclease attenuates retinal ischemia reperfusion injury through inhibition of inflammatory response and apoptosis in mice
Yun Han, Xiao Bing Zhu, Ya Ye, Kai Yu Deng, Xi Yang Zhang, Yan Song · 2020 · International Immunopharmacology
The Role of Galectin-3 in Retinal Degeneration and Other Ocular Diseases: A Potential Novel Biomarker and Therapeutic Target
Ziyi Zhou, Zhaochen Feng, Xiaojia Sun, Yusheng Wang, Guo‐Rui Dou · 2023 · International Journal of Molecular Sciences
Astrocytes and glaucomatous neurodegeneration
Ernst R. Tamm, John E. Dowling · 2017 · Experimental Eye Research
Nuevos horizontes para el tratamiento del glaucoma. I : neuroinflamación e inflamasomas
Vicente Zanón‐Moreno, Jorge Raga-Cervera, José Javier García‐Medina, Javier Benítez del Castillo Sánchez, Ignacio Vinuesa-Silva, Sergio Torregrosa, Maria Dolores Pinazo-Duran · 2017 · Archivos de la Sociedad Española de Oftalmología
Risk of glaucoma after vitreoretinal surgery – Findings from a population‐based cohort study
Sirpa Loukovaara, Erika Gucciardo, Ani Korhonen, Aapo Virtanen, Mika P. Harju, Jari K. Haukka · 2022 · Acta Ophthalmologica
Mechanisms of retinal ganglion cell injury following acute increases in intraocular pressure
Mary Anne Garner, Ryan G. Strickland, Christopher A. Girkin, Alecia K. Gross · 2022 · Frontiers in Ophthalmology
Neuronal p58IPK Protects Retinal Ganglion Cells Independently of Macrophage/Microglia Activation in Ocular Hypertension
Todd McLaughlin, Jinli Wang, Liyun Jia, Fuguo Wu, Yaqin Wang, Joshua Jianxin Wang, Xiuqian Mu, Sarah Xin Zhang · 2023 · Cells
Evaluation of Systemic Renin and Angiotensin II Levels in Normal Tension Glaucoma
Soo Ji Jeon, Hyung Bin Hwang, Na Young Lee · 2020 · Journal of Clinical Medicine
Neuropathology and Therapeutics Addressing Glaucoma, a Prevalent Retina-Optic Nerve-Brain Disease that Causes Eyesight Impairment and Blindness
Najam A. Sharif · 2022 · OBM Neurobiology
Exome Sequencing Reveals a Heterozygous OAS3 Mutation in a Chinese Family With Juvenile-Onset Open-Angle Glaucoma
Xiaoqiang Xiao, Chukai Huang, Yingjie Cao, Shaowan Chen, Yanxuan Xu, Haoyu Chen, Chi‐Pui Pang, Mingzhi Zhang · 2019 · Investigative Ophthalmology & Visual Science
A subacute model of glaucoma based on limbal plexus cautery in pigmented rats
Rafael Lani‐Louzada, Mariana Santana Dias, Carla Andreia Abreu, Victor G. Araújo, Thaís Gonçalo, Gabriel Nascimento‐dos‐Santos, Adalmir Morterá Dantas, Silvana Allodi, Mario Fiorani, Hilda Petrs‐Silva et al. · 2019 · Scientific Reports
Thermal Physics and Glaucoma: From Thermodynamic to Biophysical Considerations to Designing Future Therapies
Umberto Lucia, Giulia Grisolia · 2020 · Applied Sciences
Relationship between Periodontitis and Glaucoma: A Cross-Sectional Study
Soo‐Hwan Byun, Dae Myoung Yoo, Minwook Chang, Hyo Geun Choi, Seok Jin Hong · 2020 · Journal of Ophthalmology
Serological Levels of Anti-clathrin Antibodies Are Decreased in Patients With Pseudoexfoliation Glaucoma
Vanessa M. Beutgen, Norbert Pfeiffer, Franz H. Grus · 2021 · Frontiers in Immunology
Microglia remodeling in the visual thalamus of the DBA/2J mouse model of glaucoma
Jennifer L. Thompson, Shaylah McCool, JENNIE SMITH, Victoria L. Schaal, Gurudutt Pendyala, Sowmya V. Yelamanchili, Matthew J. Van Hook · 2025 · PLoS ONE
The gut microbiome and primary open angle glaucoma: Evidence for a ‘gut-glaucoma’ axis?
Matthew Krilis, Lewis E. Fry, Patrick Ngo, Ivan Goldberg · 2023 · European Journal of Ophthalmology
Effect of Bromfenac on Reducing Neuroinflammation in an Ischemia–Reperfusion Glaucoma Model
Si-Eun Oh, Jie‐Hyun Kim, Chan-Kee Park, Hae-Young Lopilly Park · 2024 · Cells
Development of a novel SupraChoroidal-to-Optic-NervE (SCONE) drug delivery system
Bryce Chiang, Kathleen Heng, Kyeongwoo Jang, Roopa Dalal, Yaping Joyce Liao, David J. Myung, Jeffrey Louis Goldberg · 2024 · Drug Delivery
The Role of Gut Microbiota in the Pathogenesis of Glaucoma: Evidence from Bibliometric Analysis and Comprehensive Review
Zabeeh Ullah, Yuanyuan Tao, Amina Mehmood, Jufang Huang · 2024 · Bioengineering
Fluoxetine Protects Retinal Ischemic Damage in Mice
Giovanni Luca Romano, Lucia Gozzo, Oriana Maria Maurel, Serena Di Martino, Valentina Riolo, Vincenzo Micale, Filippo Drago, Claudio Bucolo · 2023 · Pharmaceutics
A novel viewpoint in glaucoma therapeutics: enriched environment
Ruth E. Rosenstein, María Florencia González Fleitas, Damián Dorfman · 2021 · Neural Regeneration Research
New horizons for the treatment of glaucoma. I: Neuroinflammation and inflammasomes
Vicente Zanón‐Moreno, Jorge Raga-Cervera, José Javier García‐Medina, J. Benitez-del-Castillo, Ignacio Vinuesa-Silva, Sergio Torregrosa, Maria Dolores Pinazo-Duran · 2018 · Archivos de la Sociedad Española de Oftalmología (English Edition)
Long segment 3D double inversion recovery (DIR) hypersignal on MRI in glaucomatous optic neuropathy
Thomas Sartoretti, Jörg Peter Egon Stürmer, Elisabeth Sartoretti, Arash Najafi, Árpád Schwenk, Michael Wyss, Christoph A. Binkert, Sabine Sartoretti‐Schefer · 2019 · BMC Ophthalmology
Beyond IOP: Neuroprotection and neuroregeneration as important therapeutic strategies for glaucoma
Shivani Makhijani, Deepak Shamrao Khobragade · 2026 · Biomedicine & Pharmacotherapy
Natural History of Optic Disc With Physiologic Large Cup: Incidence, Predictors of Glaucoma Conversion After Minimum 10-Year Follow-up
Sooyeon Choe, Young Kook Kim, Ki Ho Park, Hyuk Jin Choi, Jin Wook Jeoung · 2023 · American Journal of Ophthalmology
Integrated Bioinformatics-Based Identification and Validation of Neuroinflammation-Related Hub Genes in Primary Open-Angle Glaucoma
Zakir Ullah, Yuanyuan Tao, Jufang Huang · 2024 · International Journal of Molecular Sciences
Caveolin-1 protects retinal ganglion cells in glaucoma by reducing TLR4 and activating the Akt/PTEN signaling pathway
Liwei Zhang, Wen Chu, Xiaoxiao Feng, Juanjuan Li, Yuling Ren, Yabin Yang, Zhikun Zheng, Hua Li · 2024 · Pathology - Research and Practice
Coinheritance of OLFM2 and SIX6 variants in a Chinese family with juvenile-onset primary open-angle glaucoma: A case report
Xue Yang, Nannan Sun, Zhenni Zhao, Shuxiang He, Miao Zhang, Dandan Zhang, Xiaowei Yu, Jiamin Zhang, Zhigang Fan · 2021 · World Journal of Clinical Cases
Optic Nerve Head Gene Transcription Sequelae to a Single Elevated IOP Exposure Provides Insights Into Known Responses to Chronically Elevated IOP
Diana C. Lozano, Hari Jayaram, William O. Cepurna, Shandiz Tehrani, Lina Gao, Suzanne S. Fei, Dongseok Choi, Elaine C. Johnson, John C. Morrison · 2023 · Investigative Ophthalmology & Visual Science
Age-related deficits in retinal autophagy following intraocular pressure elevation in autophagy reporter mouse model
Brianna C. Afiat, Da You Zhao, Vickie H. Y. Wong, Nirma D. Perera, Bradley J. Turner, Christine T. O. Nguyen, Bang Viet Bui · 2023 · Neurobiology of Aging
Identification of Optic Nerve–Related Biomarkers in Primary Open-Angle Glaucoma Based on Comprehensive Bioinformatics and Mendelian Randomization
Sijie Zhao, Qing Dai, Zixuan Rao, Juan Li, Aiqin Wang, Ziqing Gao, Yu-Chen Fan · 2024 · Translational Vision Science & Technology
Evaluating the association between autoimmune disease and normal tension glaucoma: a retrospective case-control study
Clara M. Castillejo Becerra, Robert O. Funk, Darrell Kohli, David O. Hodge, Gavin W. Roddy · 2025 · BMC Ophthalmology
Complement Factor B Inhibition or Deletion Is Not Sufficient to Prevent Neurodegeneration in a Murine Model of Glaucoma
Katie Dolan, Sha-Mei Liao, Maura A. Crowley, Chuanxi Xiang, Christopher M. Adams, Ann Brown, Nhi Vo, Amy Chen, Omar Delgado, Natasha M. Buchanan et al. · 2024 · Journal of Ocular Pharmacology and Therapeutics
In Vivo Small Molecule Delivery to the Optic Nerve in a Rodent Model
Shandiz Tehrani, R. Katherine Delf, William O. Cepurna, Lauren Davis, Elaine C. Johnson, John C. Morrison · 2018 · Scientific Reports
Association between life’s essential 8 cardiovascular health score and glaucoma risk: evidence from NHANES
Xiangxiang Fu, Xuchong Pan, Yiran Hu, Zhenni Du, Qianwei Zhu, Quanyong Yi, Fangfang Han · 2025 · International Ophthalmology
Pharmacological restoration of impaired autophagy in retinal ganglion cells prevents abnormal mitochondrial accumulation and glaucomatous neurodegeneration
Prabhavathi Maddineni, Balasankara Reddy Kaipa, Bindu Kodati, Karthikeyan Kesavan, Linya Li, J Cameron Millar, Sam Yacoub, Ramesh B. Kasetti, Abbot F. Clark, Gulab S Zode · 2026 · Molecular Neurodegeneration
Nanomedicine for neuroinflammation modulation: Next-generation nano-immunotherapies for neurodegenerative disorders
Irra Dhar, Sunidhi Bhatt, Swati Gupta, Sujeet Kumar Singh, Abhishek Dadhich · 2026 · Next Nanotechnology
Casein kinase-2 inhibition promotes retinal ganglion cell survival after acute intraocular pressure elevation
Meng Wang, Shiqi Yao, Yao Huang, Jiajian Liang, Yanxuan Xu, Shaowan Chen, Yuhang Wang, Tsz Kin Ng, Wai Kit Chu, Qi Cui et al. · 2023 · Neural Regeneration Research
Retrolaminar Demyelination of Structurally Intact Axons in Nonhuman Primate Experimental Glaucoma
Priya Chaudhary, Howard Lockwood, Cheri Stowell, Eric A. Bushong, Juan F. Reynaud, Hongli Yang, Stuart K. Gardiner, Galen A. Williams, Imee Williams, Mark H. Ellisman et al. · 2024 · Investigative Ophthalmology & Visual Science
Mechanical property changes of glial LC and RGC axons in response to high intraocular pressure
Bochao Ma, Liu Liu, Yushu Liu, Jifeng Ren, Xiuqing Qian · 2025 · Frontiers in Bioengineering and Biotechnology
Fecal microbiota transplantation for glaucoma; a potential emerging treatment strategy
Rasoul Ebrahimi, Yeganeh Farsi, Seyed Aria Nejadghaderi · 2024 · Current Research in Microbial Sciences
HOCPCA Exerts Neuroprotection on Retinal Ganglion Cells by Binding to CaMKIIα and Modulating Oxidative Stress and Neuroinflammation in Experimental Glaucoma
Panpan Li, Xin Shi, Hanhan Liu, Yuan Feng, Xiaosha Wang, Marc Herb, Haichao Ji, Stefan Wagner, Johannes Vogt, Verena Prokosch · 2025 · Neuroscience Bulletin
Analysis of Glaucoma Associated Genes in Response to Inflammation, an Examination of a Public Data Set Derived from Peripheral Blood from Patients with Hepatitis C
Jacob K Player, Sean M. Riordan, R. Scott Duncan, Peter Koulen · 2022 · Clinical ophthalmology
When is a control not a control? Reactive microglia occur throughout the control contralateral visual pathway in experimental glaucoma
James R. Tribble, Eirini Kokkali, Amin Otmani, Flavia Plastino, Emma Lardner, Rupali Vohra, Miriam Kolko, Helder André, James E Morgan, Pete A. Williams · 2019 · bioRxiv (Cold Spring Harbor Laboratory)