Neuroinflammation in glaucoma: A new opportunity

Williams, Pete A., Marsh-Armstrong, Nick, Howell, Gareth R., Bosco, Alejandra, Danias, John, Simon, John, Di Polo, Adriana, Kuehn, Markus H. +3 more·2017·Experimental Eye Research

Cited by (252)

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  2. Multifunctional Protein Alpha2-Macroglobulin in Tear Fluid and Blood Serum of Patients with Glaucoma
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  10. Protective Effects of Lipoxin A 4 and B 4 Signaling on the Inner Retina in a Mouse Model of Experimental Glaucoma
    Hsin-Hua Liu, Paul Francis Cullen, Jeremy M. Sivak, Karsten Gronert, John G. Flanagan · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  11. Identification of Sequential Molecular Mechanisms and Key Biomarkers in Early Glaucoma by Integrated Bioinformatics Analysis
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  12. Lights and Shadows of Cytokines in Age‐Related Eye Diseases: A Narrative Literature Review
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  13. Regulation of Retinal Microglia by Framework Nucleic Acid‐Mediated Delivery of microRNA‐124 Protects Retinal Ganglion Cells in Acute Glaucoma
    Cheng Zhang, Lemeng Feng, Weiming Zhu, Min He, Chao Wang, Ye He, Wulong Zhang, Jiayi Li, Haoze Song, Weitao Song · 2025 · Advanced Healthcare Materials
  14. IL-1β-mediated interaction between Müller cells and microglia through CXCL1/5-CXCR2 aggravates visual dysfunction in experimental glaucoma
    Xiaoyu Xin, Luying Han, Yuntao Qu, Lujia Zhang, Xiaoli Zhang, Jiarui Li, Bo Lei, Yong-Chen Wang, Zhongfeng Wang · 2026 · Journal of Neuroinflammation
  15. Neuroinflammation in glaucoma: a myriad of cellular pathways and players
    Michael MacLean, Sean D. Lydon, Cátia Gomes, Elizabeth M. Pizzi, Cory A. Diemler, Sarah E. R. Yablonski, Gareth R. Howell, Jason S. Meyer, Richard T. Libby · 2026 · Mammalian Genome
  16. Microglia suppress Müller cell FGF1 and contribute to retinal ganglion cell degeneration in glaucoma
    Yang Sui, Siti Tong, Zhe Qin, Pingxiu Dang, Tianyi Sui, Yabo Ma, Jiabin Wang, Yajing Zhao, Shipeng Wang, Shaojun Wang et al. · 2026 · Experimental Eye Research
  17. The role of eNOS gene polymorphisms in immunopathogenesis of primary open-angle glaucoma
    О. А. Свитич, Aliya R. Kinkulkina, Asmik Avagyan, Tatyana V. Gavrilova · 2022 · Journal of microbiology epidemiology immunobiology
  18. Association between polymorphic eNOS gene markers and risk of primary open-angle glaucoma in the Perm Region population
    Tatyana V. Gavrilova, Aliya R. Kinkulkina, Hasmik S. Avagyan, О. А. Свитич · 2022 · Russian Journal of Immunology
  19. Targeting the role of angiogenesis, inflammation and oxidative stress in pathogenesis of glaucoma: Strategic nanotechnology based drug delivery approaches
    Neelam Sharma, Neha Tiwary, Sukhbir Singh, Sumeet Gupta, Tapan Behl, Gaurav Malik · 2024 · Elsevier eBooks
  20. Glaucoma: Mechanisms of Neurodegeneration
    Lauren Katie Wareham, Melissa Cooper, David John Calkins · 2020 · Elsevier eBooks
  21. Insights into the Immune System and Glaucoma
    Jennifer L. Kielczewski · 2017 · The Ophthalmology - Open Journal
  22. PROGNOSIS OF POSTOPERATIVE PROGRESSION OF GLAUCOMA OPTIC NEUROPATHY AT PRIMARY OPEN-ANGLE GLAUCOMA
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  23. Cell-specific roles for CASK in the pathology of Optic Nerve Hypoplasia
    Alicia Kerr · 2019 · VTechWorks (Virginia Tech)
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    Benn Tonderai-Katsamudanga, Jorge A. Pérez-León · 2021 · Revista de Fomento Social
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  27. Role of Serum Albumin-and Bilirubin Biomarkers in Glaucoma Patients
    Rubia Ahmad, Maria Sarfaraz, Muhammad Faisal Javaid, Alia Sarfaraz, Ahsan Farooq, Muhammad Nazir Awan · 2022 · Pakistan Journal of Medical and Health Sciences
  28. Various forms of glaucoma and their treatments
    Najam A. Sharif · 2022 · Elsevier eBooks
  29. Análisis de la relación entre estido de vida mediterráneo, dieta y glaucoma en el proyecto SUN (Seguimiento Universidad de Navarra)
    Elsa Gándara · 2022
  30. Inflammatory and immunological aspects of glaucoma, optic neuritis, and neuromyelitis optica impacting eyesight
    Najam A. Sharif · 2023 · Elsevier eBooks
  31. Effects of Brimonidine on Microglia Morphology in the Transient Retinal Ischemia Model
    Selcan Ekicier Acar, M. Sinan Sarıcao ̆ glu, Aysel Çolak, Zeynep Akta ̧s, Aylin Sepici Dinçel · 2023 · BOHR International Journal of Current Research in Optometry and Ophthalmology
  32. A glance on antioxidants: The role of sulfur amino acids in retinal disorders
    Vanessa Castelli, Lauren A. Byrd-Leotis, Rubina Novelli, Laura Brandolini, Annamaria Cimini, Marcello Allegretti · 2023 · Elsevier eBooks
  33. Gene Therapy for Neurodegeneration in Glaucoma
    Jamie J. Karl, Henry C. Tseng · 2024 · Essentials in ophthalmology/Essentials ophthalmology
  34. Silencing circRUFY1 protects retinal ganglion cell injury in acute intraocular hypertension by activating the ERK pathway through miR-196a-5p/CALM3 axis
    BinBin Li, S Li, Wei Tang, Min Zeng · 2024 · Molecular & Cellular Toxicology
  35. Inflammasomes in Diseases of the Posterior Segment
    S. Coyle, Victoria McGilligan, Colin Eric Willoughby, Meredith S. Gregory-Ksander · 2024 · Elsevier eBooks
  36. Research Progress of the PI3K/AKT Signaling Pathway in Ophthalmic Diseases
    佳乐 王 · 2025 · Journal of Clinical Personalized Medicine
  37. Preventive role of rottlerin in endotoxin-induced uveitic glaucoma in rats
    Nidhi Kumari, Ashmita Das, Nirdesh Kumar, Geeta Singh, Urvashi Jain, Amrita Singh, Surendra Haribhau Bodakhe · 2025 · Future Journal of Pharmaceutical Sciences
  38. Machine Learning-Derived Diverse Regulated Cell Death Patterns for Therapeutic Target Identification in Glaucoma
    Qianxue Mou, Gaigai Li, Sifei Xiang, Yin Zhao, Ke Yao · 2025 · International Journal of General Medicine
  39. Additional file 1 of AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
    Nicolás Belforte, Jessica Agostinone, Luis Alarcón-Martínez, Deborah Villafranca‐Baughman, Florence Dotigny, Jorge Cueva Vargas, Adriana Di Polo · 2021 · Figshare
  40. Additional file 2 of AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
    Nicolás Belforte, Jessica Agostinone, Luis Alarcón-Martínez, Deborah Villafranca‐Baughman, Florence Dotigny, Jorge Cueva Vargas, Adriana Di Polo · 2021 · Figshare
  41. Cell-intrinsic vulnerability and immune activation cooperate to drive degeneration in a mitochondrial complex I deficiency model of optic neuropathy
    Daniela Santamaría-Muñoz, Raenier V. Reyes, Miranda R. Krueger, Andrea García‐Llorca, Brennan Marsh-Armstrong, Xin Duan, Yang Hu, Derek S. Welsbie, Nicholas Marsh‐Armstrong, Elisenda Sanz et al. · 2026 · Journal of Neuroinflammation
  42. Macrophage Migration Inhibitory Factor (MIF)-CD74 Signaling Pathway Mediates Trabecular Meshwork Dysfunction in Glaucoma
    Monu Monu, Lal Krishan Kumar, Prince Kumar, Gulab S Zode, Pawan Kumar Singh · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Lactylation-Associated Immune Metabolic Reprogramming Identifies S100A2 and S100A14 as Candidate Diagnostic Biomarkers in Primary Open-Angle Glaucoma: An Integrated Bulk and Single-Cell Transcriptomic Analysis
    Yu Xu, Xin Fu, Yajun Gong, Fangyuan Zeng, Min Tang, Sixian Hu, Guangyi Huang, Tianxian Tu, Xiaolai Zhou · 2026 · Genes
  44. The role of neuroinflammation markers in the early diagnosis of glaucoma
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  45. Electroacupuncture as an adjunctive therapy for drug-refractory primary open-angle glaucoma: a CARE-compliant case report
    Yiqing Zhang, Qihui Chen, Sibiao Lu, Hantong Hu, Qi Zhang, 刘高峰, Zhong Di · 2026 · Frontiers in Medicine
  46. Galectin-3 is elevated in Müller glia in human glaucomatous eyes and ocular hypertensive rat eyes and associated with phagocytosing states
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  47. Alopecia areata patients are associated with increased risk of glaucoma: a multicenter, retrospective cohort study
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  48. Primary Cilia of Astrocytes in the Retina in Development and Disease
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  49. Biomarkers in Glaucoma: From Diagnosis to Future Therapeutic Strategies
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  50. Angiopoietin-like protein 7 (ANGPTL7)-mediated effects on resident immune cells contribute to neurodegeneration in glaucomatous optic nerve head
    Thomas R. Vollmer, Katie Dolan, Chuanxi Xiang, Angela Banks, Eileen M. Cooney, Jessica Heyder, Charles C. King, Joanna Vrouvlianis, Akshata N Gujar, Nathaniel D. Kirkpatrick et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Glaucoma neurodegeneration: targeted modulation of intraocular immune pathways – a review of novel therapeutic advances
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  52. AKAP1 Protects Retinal Ganglion Cells and Preserves Vision by Improving Mitochondrial and Synaptic Health in Glaucomatous Neurodegeneration
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