Cited by 186Spinal Cord Injury ResearchAnimal testing and alternativesMultiple Sclerosis Research Studies

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Replication and reproducibility in spinal cord injury research

Steward, Oswald, Popovich, Phillip G., Dietrich, W. Dalton, Kleitman, Naomi·2012·Experimental Neurology

DOI 10.1016/j.expneurol.2011.06.017

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Abstract

This special issue of Experimental Neurology compiles a series of papers that either explicitly replicate published studies or retest phenomena reported in previous publications. The explicit replications were carried out as part of the "Facilities of Research Excellence-Spinal Cord Injury" (FORE-SCI) program launched by the National Institute of Neurological Disorders and Stroke (NINDS) in 2003. Here, we review the FORE-SCI replication experiments published prior to those in this special issue. We then discuss emerging issues regarding replication and reproducibility in spinal cord injury research, especially in terms of potential translation to clinical trials.

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Authors: Steward, O., Popovich, P. G., Dietrich, W. D., & Kleitman, N.
Affiliations: University of California, Irvine (US)
The Ohio State University (US)
University of Miami (US)
National Institutes of Health (US)
Corresponding author: Steward, Oswald
ORCID: Steward, Oswald
Popovich, Phillip G.
Dietrich, W. Dalton
Kleitman, Naomi
Venue: Experimental Neurology
Publisher: Elsevier BV
Published: 2012-02
Volume: 233
Issue: 2
Pages: 597-605
ISSN: 0014-4886 (ISSN-L)
DOI: 10.1016/j.expneurol.2011.06.017
OpenAlex: W2085512194
Cited by: 186
References: 52
Citations by year: 2026: 12 · 2025: 3 · 2024: 7 · 2023: 8 · 2022: 10 · 2021: 10 · 2020: 12 · 2019: 15 · 2018: 15 · 2017: 11 · 2016: 18 · 2015: 20 · 2014: 25 · 2013: 10 · 2012: 10
FWCI: 10.10
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Experimental Neurology (publishedVersion)
PubMed (publishedVersion)
Funders: N01-NS-3-2353
HHSN271200800039C
HHSN271200800040C
N01-NS-3-2352
Topics: Health Sciences › Medicine › Clinical Neurology › Spinal Cord Injury Research
Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
Health Sciences › Medicine › Clinical Neurology › Multiple Sclerosis Research Studies
Keywords: spinal cord injury, replication study, reproducibility, clinical translation, translational research, research reproducibility
MeSH terms: Humans, Pilot Projects, Spinal Cord Injuries, Reproducibility of Results, Biomedical Research

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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Replication and reproducibility in spinal cord injury research

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